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KAJIAN ETNOFARMAKOLOGI SUKU MARAE TERHADAP PENGOBATAN TRADISIONALDI DESA KEWAR KECAMATAN LAMAKNEN KABUPATEN BELU Ni Nyoman Yuliani; Maria Hilaria; Elisma Elisma; Jefrin Sambara
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.11457

Abstract

Ethnopharmacology is a part of ethnobotany that studies specifically the use of plants for treatment by certain traditional ethnic groups/communities. Ethnopharmacology becomes the spearhead in the search for new active components/substances present in plants. While ethnopharmacology studies are studies of the use of plants that function as medicines or herbs produced by local residents for treatment. The tribe studied in this study is the Marae tribe, which examines the traditional herbs or herbs used by the Marae tribe in treating the illness, this type of research is a descriptive research and using a sampling technique that is purposive sampling. This research was conducted in an interview. The results of this study found 29 types of traditional medicinal plants used by the Marae tribe society in traditional medicine. Many traditional plants have the same regional name as Indonesia, and the most common use of plants is leaves with a percentage (38%), compared to others namely, bark (28%), fruit (24%), rhizome (6%), and interest (4%) the way of utilization used by Marae tribe society including boiling (72%), pounding (17%), chewing (7%), and smeared (4%). The properties of the plants used are high blood pressure, broken bones, diabetes, malaria, ulcers, vomiting blood, bleeding, appendicitis and lungs
Effect of Basil Leaves (Ocimum sanctum L.) Infusion as Hepatoprotective Agent Induced by Paracetamol Ni Nyoman Yuliani; Jefrin Sambara; Maria Hilaria; Harlinda Harlinda
Indonesian Journal of Cancer Chemoprevention Vol 7, No 2 (2016)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev7iss2pp68-73

Abstract

Indonesia has  biodiversity potential to be developed as medicinal plants, such as basil leaves (Ocimum sanctum L.). Basil was reported to have a very high antioxidant activity in vitro. The aim of this study was to determine the effect of basil leaves (Ocimum sanctum L.) infusion to liver based Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) value in each dose. 18 rats were divided into 6 groups.,  control group,  negative control group treated with CMC Na 0.5%,  positive control group treated with Curcuma 3.6 mg / 200gBB, groups of 4-6 consecutive given a 80 mg  dose infusion basil / 200 gBB, 160 mg / 200 gBB, 320 mg / 200 gBB for 8 consecutive days, on the day of the 4th and 8th all treatment groups induced by toxic doses of paracetamol (500 mg / 200 gBB) except the normal control group 1, The research data in the form of enzyme activity of AST and ALT were analyzed using parametric and nonparametric ANOVA, and Friedman test with the level of trust  then followed by SNK test and Bnj test. The statistical test result with a 95% of level of trust that shown basil infuse with a dose of 80mg / 200gBB, 160mg / 200gBB, 320mg / 200gBB have hepatoprotective effects in rats induced by paracetamol 500mg / 200gBB. Based on the result of changes in average levels of AST on the fourth day and the eighth day of the three treatment infusion, infusion at a dose of 160 mg / 200gBB most effectively reduce average levels of AST and a group that has the average AST closest to the control group is positive, but infusion at a dose of 320mg / 200gBB the group that has the closest average ALT positive control group.Keywords : hepatoprotective, Ocimum sanctum L, Paracetamol
Hubungan penyajian susu formula dengan kejadian diare pada bayi di Puskesmas Pahandut Martha, Putri Ellya; Arifin, Syamsul; Yuliani, Ni Nyoman
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 2 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i2.7998

Abstract

Diarrhea is a change in consistency that happened suddenly due to the water content in the feces exceeding normal in baby and toddlers with a frequency increase of defecation more than 4 times in 24 hours. Baby formula is a good medium for the growth of bacteria and is also easily contaminated if the presentation does not pay attention to the hygienic aspect. This research used analytic observational method with a cross sectional research approach on 93 respondents of mother who have babies < 12 months and used statistical test chi square with significant level < 0,005. The results of the study found that the occurence diarrhea was dominated by the presentation of unhygienic baby formula (55.6%). The results of the bivariate analysis in this research showed that there was a significant relationship between the method of serving baby formula for diarrhea in the UPT BLUD Puskesmas Pahandut with the results of the chi square statistical test showing that the value of p = 0.009 (p < 0.05). There is a connection between the method of serving baby formula and the occurence of diarrhea in the working area of ​​BLUD UPT Puskesmas Pahandut.
Ethnomedical Study of Traditional Medicinal Plants for Cough and Tuberculosis (TB) of the Helong Tribe on Semau Island, Kupang Regency, East Nusa Tenggara Korassa, Yulius Baki; Blegur, Fatmawati; Sambara, Jefrin; Yuliani, Ni Nyoman; Upa, Satria Mandala Pua
Journal of Comprehensive Science Vol. 3 No. 8 (2024): Journal of Comprehensive Science (JCS)
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v3i8.849

Abstract

The Helong people in Kupang Regency, NTT Province, have experienced being exposed to cough and tuberculosis (TB). Therefore, it is believed that this community has also long since developed their local knowledge and traditional ways to prevent and treat the disease. In general, this study aims to analyze and find the concept of the Helong Tribe community and ethnomedical practices for the prevention and treatment of cough and tuberculosis (TB). This research is a medical anthropology research using a qualitative research method with an ethnographic approach, which is supported by laboratory research and literature studies. Field research was carried out on Semau Island, NTT Province, involving traditional medicine. The results of the research conducted in the form of interviews with traditional medicine practitioners in the Helong tribe obtained as many as 31 plants used in treatment, and there were 3 plants used to treat cough, including hemorrhagic cough/tuberculosis, namely plants: white banyan (Ficus benjamina L), mesocarp palm fruit (Borassus flabellifer L.) and white flower (Clerodendrum costatum R.Br). The three plants that are suspected to have the ability to treat cough and cough up blood carried out preliminary tests of antibacterial activity against bacteria that generally cause stones, namely Staphylococcus aureus bacteria. The results obtained for ethanol extract of white banyan leaves (Ficus benjamina L) with a concentration of 25% b/v with a diameter of 16.53 mm, 50% b/v with a diameter of 16.33 mm, and 75% b/v with a diameter of 16.56 mm. Mesocarp ethanol extract of palm fruit (Borassus flabellifer L.) At a concentration of 25% b/v with an inhibitory zone diameter of 11.60 mm, a concentration of 50% b/v with an inhibitory zone diameter of 12.30 mm, a concentration of 75% b/v with an inhibitory zone diameter of 13.40 mm, for white flowers (Clerodendrum costatum R.Br) at a concentration of 25%b/v with an inhibitory zone diameter of 9.41 mm, a concentration of 50% b/v of 10.36 mm and a concentration of 75% b/v of 11.24 mm. This means that the three plants have antibacterial activity against Staphylococcus aureus bacteria. Furthermore, for the antibacterial activity test against Mycobacterium tuberculosis bacteria for white banyan plants (Ficus benjamina L.), mesocarp of palm fruit (Borassus flabellifer L.), and white flowers (Clerodendrum costatum R.Br) by the MODS (Microscopically Observed Drug Susceptibility) method, it was obtained that the three plants at concentrations of 250 ppm, 500 ppm, and 1000 ppm were only seen to have the growth of Micobacterium tuberculosis bacteria in the second week. Passive control with INH observation until week IV did not see any bacterial growth, while for negative control in the first week, the growth of Mycobacterium tuberculosis bacteria was seen. It can be concluded that a concentration greater than 1000 ppm is needed for the three plants to inhibit the growth of Mycobacterium tuberculosis bacteria.