Polycystic Ovary Syndrome (PCOS) is a hormonal disorder distinguished by irregular menstrual cycles, elevated androgen levels, and the presence of polycystic ovaries, impacting approximately 4-18% of women of reproductive age. This condition can lead to infertility, with obesity exacerbating its manifestations by elevating testosterone levels and contributing to insulin resistance. Various factors, including dietary habits and a sedentary lifestyle, play a significant role in the prevalence of obesity, particularly in Indonesia. This research aims to explore the potential relationship between obesity, physical activity, and dietary habits concerning the prevalence of PCOS among women of reproductive age in East Java. A quantitative research design has been employed, utilizing a cross-sectional approach. The study comprises two distinct groups: one consisting of women diagnosed with PCOS and another comprising healthy women. The sampling method used is purposive sampling. The research instrument includes demographic questionnaires, Body Mass Index (BMI) calculations, dietary assessments, and the Global Physical Activity Questionnaire (GPAQ). Data analysis was conducted using SPSS version 21. The findings indicated that the obesity emerged as the most significant independent factor influencing the likelihood of PCOS occurrence (p=0.000). The Exponent Beta (Exp. B) value, calculated at 31.62, reveals that women with obesity are at a 31-fold increased risk of developing PCOS compared to their non-obese counterparts. In conclusion, there is a significant association between obesity, physical activity, and dietary habits and the occurrence of PCOS among women of childbearing age in East Java