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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Nusantara Medical Science Journal Jurnal Epidemiologi Kesehatan Komunitas Medika Kartika : Jurnal Kedokteran dan Kesehatan Health Information : Jurnal Penelitian Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Malahayati International Journal of Nursing and Health Science
Syarifah Nurul Yanti Rizki Syahab Assegaf
Departemen Farmakologi, Fakultas Kedokteran, Universitas Tanjungpura Pontianak
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Uji Aktivitas Antibakteri Air Perasan Jeruk Siam Sambas terhadap Escherichia coli Bimo Hendrayana; Mistika Zakiah; Syarifah Nurul Yanti Rizki Syahab Assegaf; Delima Fajar Liana; Mahyarudin Mahyarudin
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 1 (2025): Januari : Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i1.1021

Abstract

Escherichia coli is a bacterium that typically resides as a normal flora in the gastrointestinal tract of humans and animals. However, certain strains of E. coli can cause infections in humans. Therefore, antibiotics are needed to inhibit the growth of these infection-causing bacteria. The increasing cases of antibiotic resistance in E. coli necessitate alternative therapies, including the use of natural substances. In West Kalimantan, one potential source is the Pontianak Orange (Citrus nobilis var. microcarpa). This plant contains secondary metabolites that can be used for medicinal purposes, such as the juice extract. The compounds within these secondary metabolites possess antimicrobial properties that could be used as antibacterials. To determine the antibacterial potential of Pontianak Orange juice (Citrus nobilis var. microcarpa) against Escherichia coli. This study utilized an experimental design featuring a post-test only group design. Phytochemical analysis indicated that Pontianak Orange juice (Citrus nobilis var. microcarpa) contains phenolics (+), alkaloids (+), and terpenoids (++). Antibacterial activity testing at all concentrations (25%, 50%, 75%, and 100%) showed no inhibition zones. The juice of Pontianak Orange (Citrus nobilis var. microcarpa) did not show antibacterial effects against the growth of Escherichia coli bacteria.
Potential of Cat’s Whisker (Orthosiphon stamineus B) As Antidiabetic in Traditional Medicine of The Dayak Tribe in West Kalimantan : A Literature Review Hartono Putra, Galih Abisatya; Andayani, Sari; Qisthi, Dianelita Asyifa; Aurelion, Candra; Mochammad, Taufiq; Zakiah, Mistika; Assegaf, Syarifah Nurul Yanti Rizki Syahab
Nusantara Medical Science Journal Volume 9 Issue 2, July - December 2024
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.vi.37072

Abstract

Introduction: Diabetes mellitus or better known as diabetes is a disease characterized by the body's inability to produce insulin or the inability to use insulin (insulin resistance). The high prevalence of diabetes sufferers in Indonesia requires attention and treatment, especially through medication. One of Indonesia's advantages compared to other countries is the biodiversity and cultural diversity sector in Indonesia, namely medicinal plants. The cat's whisker plant (Orthosiphon stamineus B) can be an alternative treatment for treating complications of diabetes mellitus. Cat's whisker leaves contain orthosiphon glucose, saponins, essential oils, flavonoids, polyphenols, potassium salts and myoinositol, several substances contained in this plant have the potential to lower blood sugar levels. Methods: This writing is a literature review by collecting literature from English and Indonesian language articles from 2014-2024, most of which are research articles. Results: The search using the keywords, resulting in a final total of 5 articles to be included in the literature review. Conclusion:  This research reveals that cat's whiskers (Orthosiphon stamineus B) show potential as an effective antidiabetic agent. Treatment with Orthosiphon stamineus B extract significantly reduced blood glucose levels, increased insulin secretion, and increased ghrelin and GLP-1 levels, all of which contribute to glucose regulation
EFFECTIVENESS OF ETHANOL EXTRACT OF PURPLE EGGPLANT SKIN AS AN ANTIMALARIAL ON LIVER SIZE IN MICE INDUCED WITH Plasmodium berghei Taniyo, Nurul Fadhilah; Muhammad In'am Ilmiawan; Muhammad Ibnu Kahtan; Sari Rahmayanti; Syarifah Nurul Yanti Rizki Syahab Assegaf
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 1 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i1.454

Abstract

Malaria is caused by the protozoa Plasmodium through the bite of the Anopheles mosquito, with one of the symptoms being an enlarged liver. This study aims to test the effectiveness of ethanol extract of purple eggplant (Solanum melongena L.) skin on the liver size of mice (Mus musculus) induced by Plasmodium berghei. Extraction was carried out by maceration using 70% ethanol. Mice were divided into treatment groups (extract doses of 0.075 mg/20 gBW, 0.15 mg/20 gBW, and 0.3 mg/20 gBW), positive control (DHP 3.744 mg/20 gBW), negative control (aquades), and normal control. Observations included parasitemia levels as well as liver weight, volume, and index. The results showed that the extract dose affected the liver size of mice. There was no significant correlation between parasitemia and liver weight (p=0.073) and volume (p=0.133), but there was a significant correlation with liver index (p=0.002). This study recommends further studies on the potential of active compounds in purple eggplant as hepatoprotective and antimalarial agents.
Self-efficacy and self-care behaviours among adults with antihypertensive medication adherence Len, Jenny Firda; Assegaf, Syarifah Nurul Yanti Rizki Syahab; Ulfah, Ridha
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 8 (2025): Volume 8 Number 8
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i8.1100

Abstract

Background: Hypertension is a chronic medical condition characterized by persistently elevated systolic and diastolic blood pressure beyond normal thresholds, often termed a “silent killer.” Increased self-efficacy and effective self-care management have been shown to positively influence adherence to antihypertensive treatment. However, limited research has examined the relationship between intrinsic factors and medication adherence among patients within the Saigon Community Health Center. Purpose: To determine the relationship between self-efficacy, self-care management, and medication adherence among individuals with hypertension. Method: This research employed an analytical observational design with a cross-sectional approach. A total of 100 hypertensive patients participated, assessed using the Morisky Medication Adherence Scale (MMAS-8), the Modified General Perceived Self-Efficacy Scale, and the Hypertension Self-Management Behavior Questionnaire (HSMBQ). Univariate analysis was used to describe respondents’ demographic characteristics, while bivariate analysis was performed using Spearman’s correlation test. Results: The findings showed that 87% of respondents demonstrated good self-care management, 85% had high self-efficacy, and 51% adhered to their prescribed medications. Spearman’s correlation analysis revealed a significant relationship between self-care management and medication adherence (p = 0.002, r = 0.311), as well as between self-efficacy and adherence (p = 0.009, r = 0.262). Conclusion: Both self-efficacy and self-care management were found to have a significant but weak positive correlation with medication adherence. Strengthening patients’ motivation and promoting consistent engagement in hypertension management are essential to reducing related complications.
ANTIBACTERIAL POTENTIAL OF DAYAK ONION BULB EXTRACT (Eleutherine sp) AS A TREATMENT FOR ACNE VULGARIS: A LITERATURE REVIEW Pradhea, Tifani Antonia; Clarissa, Maria; Ridho, Muhammad; Aqsa, Sadilla; Sumarna, Dimas Aldianakhi; Assegaf, Syarifah Nurul Yanti Syahab; Zakiah, Mistika
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 8 No 4 (2025): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Acne vulgaris is a common skin disorder that can significantly affect quality of life. Although conventional antibiotic treatments are commonly used, herbal alternatives such as Eleutherine sp. (Dayak onion) bulb extract may offer therapeutic options for acne vulgaris. This study is a literature review that evaluates the antibacterial activity of Dayak onion bulb extract against bacteria that cause acne vulgaris. The search was conducted in the ScienceDirect, PubMed, Google Scholar, and Garuda databases, focusing on in vitro studies published in the last 10 years. Of the 8 articles analyzed, Dayak onion bulb extract was effective against Staphylococcus aureus, Staphylococcus epidermidis, and Propionibacterium acnes. The best antibacterial activity was obtained from extracts at high concentrations with several methods. Temperature and incubation duration also affected the results. Active compounds such as flavonoids, alkaloids, triterpenoids, steroids, and tannins contributed to the antibacterial effectiveness of this extract. Dayak onion bulb extract showed strong antibacterial effectiveness, making it a potential alternative for treating acne vulgaris. This extract as an additional therapy offers a safe option as a natural acne vulgaris treatment solution. Keywords: acne vulgaris, antibacterial, Eleutherine DOI : 10.35990/mk.v8n4.p446-457
Predictors of Medication Adherence among Hypertensive Patients at the Parit Haji Husin II Public Health Center Pontianak Zuhudan, Fahim; Syahab Assegaf, Syarifah Nurul Yanti Rizki; Nurmainah, Nurmainah
Jurnal Epidemiologi Kesehatan Komunitas Vol 11, No 1: Februari 2026
Publisher : Master of Epidemiology, Faculty of Public Health, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v11i1.30567

Abstract

Background: Hypertension remains highly prevalent, while medication adherence is still low at Parit H. Husin II Community Health Center, underscoring the importance of examining its associated factors.Methods: This analytical observational study used a cross-sectional design conducted at Parit H. Husin II Community Health Center, Southeast Pontianak, from December 2024 to January 2025. A total of 119 hypertensive patients were included. Data were collected using validated questionnaires, including the Morisky Medication Adherence Scale (MMAS-8) to assess medication adherence. Data were analyzed using univariate, Chi-square, and logistic regression tests.Result: The majority of respondents were female (61,3%), had higher education (52,1%), were unemployed (59,7%), had suffered from hypertension for less than 5 years (86,6%), had health insurance from BPJS (94,1%), had low knowledge of hypertension (52,9%), good access to health services (87,4%), high family support (63%), high support from health workers (74,8%), high motivation to seek treatment (63,9%), and adherence to antihypertensive medication (53,8%). The Chi-square test results showed a relationship between gender (p=0,218), education level (p=0,000), employment status (p=0,760), duration of hypertension (p=0,004), health insurance coverage (p=0,072), knowledge level (p=0,011), accessibility of health services (p=0,005), family support (p=0,611), role of health workers (p=0,366), motivation to seek treatment (p=0,002) with medication adherence. The results of the logistic regression test obtained the factor of duration of hypertension (OR=10,422).Conclusion: Length of time suffering from hypertension is the most influential factor on adherence to taking medication (p=0,020; OR=10,422).
Hubungan Pengetahuan dan Kepuasan terhadap Kepatuhan Minum Obat Pasien Hipertensi di UPTD Puskesmas Kampung Bali, Pontianak Syech Indah Adivanefi; Syarifah Nurul Yanti Rizki Syahab Assegaf; Nurmainah Nurmainah
Health Information : Jurnal Penelitian Vol 18 No 2 (2026): Mei-Agustus
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v18i2.1855

Abstract

Latar belakang: Ketidakpatuhan minum obat pada pasien hipertensi masih tinggi dan berpotensi menimbulkan komplikasi, sehingga faktor pengetahuan dan kepuasan terhadap pelayanan perlu dikaji di tingkat layanan primer. Tujuan: Menganalisis hubungan tingkat pengetahuan dan kepuasan dengan kepatuhan minum obat pada pasien hipertensi di UPTD Puskesmas Kampung Bali, Pontianak. Metode: Penelitian kuantitatif analitik dengan desain potong lintang pada 97 pasien hipertensi yang dipilih secara purposive. Pengetahuan diukur menggunakan Kuesioner Pengetahuan Hipertensi tervalidasi, kepuasan dengan KKP 2017 Format 10, dan kepatuhan menggunakan MMAS-8 versi Indonesia; analisis menggunakan uji Chi-square (?=0,05). Hasil: Sebagian besar responden berpengetahuan baik (56,7%), kepuasan tinggi (49,5%), dan tidak patuh minum obat (37,1%). Terdapat hubungan bermakna antara pengetahuan dan kepatuhan (p=0,008), sedangkan kepuasan tidak berhubungan dengan kepatuhan (p=0,406). Simpulan: Pengetahuan yang baik berkorelasi dengan kepatuhan minum obat. Saran: Penguatan edukasi terstruktur dan konseling individual perlu dioptimalkan di layanan primer
Co-Authors Aqsa, Sadilla Aurelion, Candra Bimo Hendrayana Clarissa, Maria Delima Fajar Liana Hartono Putra, Galih Abisatya Len, Jenny Firda Mahyarudin, Mahyarudin Mistika Zakiah Mochammad, Taufiq Muhammad Ibnu Kahtan Muhammad In'am Ilmiawan Muhammad Ridho Nurmainah Nurmainah Nurmainah Nurmainah Pradhea, Tifani Antonia Qisthi, Dianelita Asyifa Ridha Ulfah Sari Andayani Sari Rahmayanti Sumarna, Dimas Aldianakhi Syech Indah Adivanefi Taniyo, Nurul Fadhilah Zuhudan, Fahim