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All Journal Jurnal Mahasiswa PSPD FK Universitas Tanjungpura Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Kesehatan Andalas Mutiara Medika: Jurnal Kedokteran dan Kesehatan Pharmascience Universa Medicina Pontianak Nutrition Journal (PNJ) Cermin Dunia Kedokteran Makara Journal of Health Research JURNAL PENELITIAN BIDANG PENDIDIKAN Jurnal Vokasi Kesehatan Cermin Dunia Kedokteran
Sari Rahmayanti
Departement Of Parasitology, Faculty Of Medicine, Universitas Tanjungpura
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Other

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PENGARUH PENGHENTIAN PAJANAN MONOSODIUM GLUTAMAT TERHADAP KADAR MALONDIALDEHID JARINGAN TESTIS TIKUS PUTIH (Rattus norvegicus) DEWASA Puspasari, Ratih Hemiarista; Nawangsari, Nawangsari; Andriani, Andriani; Rahmayanti, Sari
Jurnal Mahasiswa PSPD FK Universitas Tanjungpura Vol 5, No 1 (2019): Jurnal Pendidikan Dokter Kalbar
Publisher : Jurnal Mahasiswa PSPD FK Universitas Tanjungpura

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Abstract

Introduction: Monosodium glutamate (MSG) is a food additive that used as a flavor enhancers that can lead to oxidative stress in testis. Food and Drugs Administration (FDA) in 1995 has established the safety limit in the usage of MSG, no more than 120 mg/kgBW/day. Oxidative stress produce unstable and reactive lipid peroksidase that caused lipid degradation and generate malondialdehid (MDA). Objective: The purpose of this research was to observe MDA levels of testes after termination of MSG exposure. Method: This research was a true experimental research with simple random sampling. The control group (K) 1,2,3 were given aquades for 28 days. The first treatment group (P1) 1,2,3 were given MSG 4 g/kgBW/day for 28 days. The second treatment group (P2) 1,2,3 were given MSG 6 g/kgBW/day for 28 days and then stopped for 1 day, 28 days, and 56 days. Then, the rats were sacrificed and the testis was processed to be homogenate and then conducted to MDA’s level measurements using Will’s Methode. Data was analyzed using one way anova test, continued with post hoc test LSD. Result: Day 1 after MSG termination, analysis showed that there were significant difference between control group and the first group treatment 1 (p=0,010) and the second group treatment 1 (p=0,000). Day 29 after MSG termination, analysis showed that there was significant difference between control group and the second group treatment 2 (p=001), also between the first and the second group treatment 2 (p=0,017) . Day 57 after MSG termination, analysis showed there were no significant difference between the control group with both treatment group and between the treatment groups 1 to the treatment group 2 in. Conclusion: Termination of MSG exposure caused discontinuation of damage in rats testes. Keywords: Rats, Testis, Monosodium Glutamate, Oxidative Stress, MDA levelsSoft File Naspub 
Hubungan antara Pengetahuan mengenai Pityriasis versicolor dan PHBS dengan Kejadian Pityriasis versicolor pada Santri Madrasah Tsanawiyah Pondok Pesantren X Kecamatan Mempawah Hilir Natalia, Diana; Rahmayanti, Sari; Nazaria, Riska
Cermin Dunia Kedokteran Vol 45, No 1 (2018): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.812 KB) | DOI: 10.55175/cdk.v45i1.148

Abstract

Pityriasis versicolor merupakan penyakit infeksi kulit yang disebabkan oleh jamur spesies Malassezia, ditemukan pada 20-25% penduduk dunia, lebih sering di area lembap dan temperatur cukup tinggi, seperti Kalimantan Barat dengan suhu rata-rata 25,8-28,33oC dan kelembapan 60- 98%. Penelitian ini menganalisis hubungan antara pengetahuan mengenai pityriasis versicolor dan PHBS dengan kejadian pityriasis versicolor di kalangan santri Madrasah Tsanawiyah (MTs) di Pondok Pesantren X Kecamatan Mempawah Hilir, menggunakan metode analitik observasional dengan pendekatan cross-sectional. Jumlah sampel sebanyak 139 orang, di mana 45 orang di antaranya menderita pityriasis versicolor. Sebanyak 57,6% subjek memiliki pengetahuan baik tentang penyakit pityriasis versicolor dan 93,3% subjek memiliki Perilaku Hidup Bersih dan Sehat (PHBS) yang baik. Tidak terdapat hubungan antara pengetahuan pityriasis versicolor dan PHBS dengan kejadian pityriasis versicolor pada santri MTs di Pondok Pesantren X Kecamatan Mempawah Hilir.Pityriasis versicolor is fungal skin infection caused by Malassezia, found in 20-25% human population, mostly in moist and high temperature area, such as in West Borneo with an average temperature 25,8-28,33°C and humidity 98%. This cross-sectional study analyzed the correlation between knowledge on pityriasis versicolor and clean and healthy behavior with pityriasis versicolor incidence among Madrasah Tsanawiyah (MTs) students in Islamic Boarding School X Subdistrict Mempawah Hilir, using an observational analytical method with a cross-sectional approach. A total of 139 students were included, 45 diagnosed with pityriasis versicolor. A proportion of 57,8% subjects had a good knowledge on pityriasis versicolor and 93,3% had a good clean and healthy behavior. No correlation between knowledge on pityriasis versicolor and clean and healthy behavior with pityriasis versicolor incidence among MTs students in Islamic Boarding School X Subdistrict Mempawah Hilir
Uji Aktivitas Antijamur Ekstrak Etanol Umbi Bawang Dayak (Eleutherine americana (Aubl.) Merr. Ex K. Heyne.) terhadap Trichophyton mentagrophytes secara In Vitro Woris Christoper; Diana Natalia; Sari Rahmayanti
Jurnal Kesehatan Andalas Vol 6, No 3 (2017)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v6i3.758

Abstract

Dermatofitosis adalah suatu infeksi pada jaringan berkeratin yang disebabkan karena adanya kolonisasi dari jamur jenis dermatofita. Salah satu spesies dermatofita yang paling banyak menginfeksi yaitu Trichophyton mentagrophytes. Tanaman bawang dayak (Eleutherine americana (Aubl.) Merr. Ex K. Heyne) merupakan tanaman yang biasa digunakan masyarakat untuk mengobati penyakit kulit. Tujuan penelitian ini adalah mengetahui aktivitas antijamur ekstrak etanol umbi bawang terhadap pertumbuhan Trichophyton mentagrophytes, mengetahui kandungan metabolit sekunder dan untuk mengetahui konsentrasi efektif larutan uji yang dapat menghambat pertumbuhan Trichophyton mentagrophytes. Metodologi penelitian ini merupakan eksperimental murni secara in-vitro dengan rancangan acak lengkap posttest only control group design. Aktivitas antijamur ekstrak diuji dengan metode difusi cakram Kirby-Bauer. Kontrol positif yang digunakan adalah itrakonazol 8 µg dan kontrol negatif adalah Tween 80 10%. Hasil penelitian adalah ekstrak etanol umbi bawang dayak memiliki aktivitas antijamur pada konsentrasi 600; 300; 150 mg/mL, KHM pada 150 mg/mL dengan zona hambat 9,15 mm, hasil skrining fitokimia didapatkan fenol,  flavonoid, tanin, saponin, dan kuinon. Simpulan studi ini ialah ekstrak etanol umbi bawang dayak memiliki aktivitas antijamur terhadap Trichophyton mentagrophytes
Hubungan antara Pengetahuan mengenai Pityriasis versicolor dan PHBS dengan Kejadian Pityriasis versicolor pada Santri Madrasah Tsanawiyah Pondok Pesantren X Kecamatan Mempawah Hilir Diana Natalia; Sari Rahmayanti; Riska Nazaria
Cermin Dunia Kedokteran Vol 45, No 1 (2018): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i1.148

Abstract

Pityriasis versicolor merupakan penyakit infeksi kulit yang disebabkan oleh jamur spesies Malassezia, ditemukan pada 20-25% penduduk dunia, lebih sering di area lembap dan temperatur cukup tinggi, seperti Kalimantan Barat dengan suhu rata-rata 25,8-28,33oC dan kelembapan 60- 98%. Penelitian ini menganalisis hubungan antara pengetahuan mengenai pityriasis versicolor dan PHBS dengan kejadian pityriasis versicolor di kalangan santri Madrasah Tsanawiyah (MTs) di Pondok Pesantren X Kecamatan Mempawah Hilir, menggunakan metode analitik observasional dengan pendekatan cross-sectional. Jumlah sampel sebanyak 139 orang, di mana 45 orang di antaranya menderita pityriasis versicolor. Sebanyak 57,6% subjek memiliki pengetahuan baik tentang penyakit pityriasis versicolor dan 93,3% subjek memiliki Perilaku Hidup Bersih dan Sehat (PHBS) yang baik. Tidak terdapat hubungan antara pengetahuan pityriasis versicolor dan PHBS dengan kejadian pityriasis versicolor pada santri MTs di Pondok Pesantren X Kecamatan Mempawah Hilir.Pityriasis versicolor is fungal skin infection caused by Malassezia, found in 20-25% human population, mostly in moist and high temperature area, such as in West Borneo with an average temperature 25,8-28,33°C and humidity 98%. This cross-sectional study analyzed the correlation between knowledge on pityriasis versicolor and clean and healthy behavior with pityriasis versicolor incidence among Madrasah Tsanawiyah (MTs) students in Islamic Boarding School X Subdistrict Mempawah Hilir, using an observational analytical method with a cross-sectional approach. A total of 139 students were included, 45 diagnosed with pityriasis versicolor. A proportion of 57,8% subjects had a good knowledge on pityriasis versicolor and 93,3% had a good clean and healthy behavior. No correlation between knowledge on pityriasis versicolor and clean and healthy behavior with pityriasis versicolor incidence among MTs students in Islamic Boarding School X Subdistrict Mempawah Hilir
Infections of Chlamydia trachomatis and Mycoplasma hominis as Risk Factors for Abnormal Cervical Cells Mardhia, Mardhia; Effiana, Effiana; Irsan, Abror; Natalia, Diana; Rahmayanti, Sari; Indarti, Junita; Rachmadi, Lisnawati; Yasmon, Andi
Makara Journal of Health Research Vol. 22, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Cervical cancer is the fourth most common cancer among women across the world. Recent studies have shown that cervical cancer is not only caused by persistent infection of human papillomavirus (HPV), but sexually transmitted infections (STIs) also play a role in the pathogenesis of abnormal cervical cells. STIs frequently occur with no specific symptoms, such as the infections caused by Chlamydia trachomatis and Mycoplasma hominis. Asymptomatic STIs could lead to persistent infection. Persistent infections caused by STIs have been hypothesised to increase the access of HPV into the deeper cervical tissue and cause cervical cell abnormalities. Therefore, we conducted this study to assess the association between C. trachomatis and M. hominis infections and abnormal cervical cells. Methods: A cross-sectional study was performed on 58 outpatients at the Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Abnormal cervical cells were detected by a liquid-based cytology Pap smear, and bacterial identification was done by conducting conventional duplex polymerase chain reaction (PCR). Results: 58 patients, 14 (24.1%) showed abnormal cervical cells, whereas 44 (75.9%) patients showed normal cervical cells. The conventional duplex PCR demonstrated a positive result for C. trachomatis and M. hominis bacterial infections in only 1 (7.1%) and 2 (14.3%) patients with abnormal cervical cells, respectively. The statistical analysis revealed no significant association between the bacterial infections and the abnormal cervical cytology in the patients (p > 0.05). Conclusions: Infections caused by C. trachomatis and/or M. hominis were not associated with abnormal cervical cells.
Hubungan antara Pengetahuan mengenai Pityriasis versicolor dan PHBS dengan Kejadian Pityriasis versicolor pada Santri Madrasah Tsanawiyah Pondok Pesantren X Kecamatan Mempawah Hilir Diana Natalia; Sari Rahmayanti; Riska Nazaria
Cermin Dunia Kedokteran Vol 45 No 1 (2018): Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i1.832

Abstract

Pityriasis versicolor merupakan penyakit infeksi kulit yang disebabkan oleh jamur spesies Malassezia, ditemukan pada 20-25% penduduk dunia, lebih sering di area lembap dan temperatur cukup tinggi, seperti Kalimantan Barat dengan suhu rata-rata 25,8-28,33°C dan kelembapan 60-98%. Penelitian ini menganalisis hubungan antara pengetahuan mengenai pityriasis versicolor dan PHBS dengan kejadian pityriasis versicolor di kalangan santri Madrasah Tsanawiyah (MTs) di Pondok Pesantren X Kecamatan Mempawah Hilir, menggunakan metode analitik observasional dengan pendekatan cross-sectional. Jumlah sampel sebanyak 139 orang, di mana 45 orang di antaranya menderita pityriasis versicolor. Sebanyak 57,6% subjek memiliki pengetahuan baik tentang penyakit pityriasis versicolor dan 93,3% subjek memiliki Perilaku Hidup Bersih dan Sehat (PHBS) yang baik. Tidak terdapat hubungan antara pengetahuan pityriasis versicolor dan PHBS dengan kejadian pityriasis versicolor pada santri MTs di Pondok Pesantren X Kecamatan Mempawah Hilir.   Pityriasis versicolor is fungal skin infection caused by Malassezia, found in 20-25% human population, mostly in moist and high temperature area, such as in West Borneo with an average temperature 25,8-28,33°C and humidity 98%. This cross-sectional study analyzed the correlation between knowledge on pityriasis versicolor and clean and healthy behavior with pityriasis versicolor incidence among Madrasah Tsanawiyah (MTs) students in Islamic Boarding School X Subdistrict Mempawah Hilir, using an observational analytical method with a cross-sectional approach. A total of 139 students were included, 45 diagnosed with pityriasis versicolor. A proportion of 57,8% subjects had a good knowledge on pityriasis versicolor and 93,3% had a good clean and healthy behavior. No correlation between knowledge on pityriasis versicolor and clean and healthy behavior with pityriasis versicolor incidence among MTs students in Islamic Boarding School X Subdistrict Mempawah Hilir.
RELATIONSHIP BETWEEN HEMATOCRIT, PLATELETS AND PLATELET-TO-LYMPHOCYTE RATIO WITH LENGTH OF STAY IN CHILDREN WITH DHF Sari Rahmayanti
Jurnal Vokasi Kesehatan Vol 7, No 1 (2021): JANUARI 2021
Publisher : Poltekkes Kemenkes Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (291.606 KB) | DOI: 10.30602/jvk.v7i1.659

Abstract

Dengue Hemorrhagic Fever (DHF) is still health problem in Indonesia. DHF cause big impact to public health and create economic problems. The purpose of this study was to determine the relationship between hematocrit, platelet and platelet-to-lymphocite ratio with the length of stay of children with DHF who were treated at the Sultan Syarif Mohammad Alkadrie Hospital throughout 2019. This study was conducted with cross-sectional design and the data was obtained from the medical records in Sultan Syarif Mohamad Alkadrie Hospital. The sample’s data was collected using total sampling method with a sample size of 79 people.  The data were analyzed using Mann-Whitney test and Pearson test. This study found there is relationship between hematocrit (p=0,000) with length of stay in children with DHF and no significant relationship between platelets (p=0.173) and platelet-to-lymphocyte ratio (p=0.319) with length of stay in children with DHF.
EFEKTIVITAS PEMBELAJARAN SISTEM BLOK SELAMA MATRIKULASI TERHADAP TINGKAT PENGETAHUAN MAHASISWA KEDOKTERAN UNIVERSITAS TANJUNGPURA Sari Rahmayanti; Puji Astuti
JURNAL PENELITIAN BIDANG PENDIDIKAN Vol 30, No 1 (2024)
Publisher : LPPM Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpbp.v30i1.52290

Abstract

Sistem blok merupakan metode pembelajaran student-centered yang telah banyak diterapkan di institusi pendidikan Kesehatan di Indonesia. Banyak mahasiswa baru mengalami kesulitan dalam beradaptasi dengan situasi pembelajaran mereka, dimana sebelumnya metode pembelajaran mereka adalah teacher-centered dan kini berubah menjadi student-centered. Matrikulasi merupakan program penyesuaian yang diselenggarakan oleh perguruan tinggi dengan tujuan untuk mempercepat kemampuan adaptasi akademik maupun non-akademik mahasiswa baru di perguruan tinggi. Penelitian ini bertujuan untuk mengetahui efektivitas pembelajaran sistem blok selama matrikulasi terhadap tingkat pengetahuan mahasiswa Program Studi S1 Kedokteran Universitas Tanjungpura. Penelitian ini merupakan penelitian kuantitatif menggunakan metode eksperimen dengan jenis penelitian berupa quasi experimental. Rancangan yang digunakan pada penelitian ini merupakan one group pre-test post-test design. Teknik pengumpulan data dilakukan dengan menggunakan kuisioner. Sampel diambil dengan metode total sampling yaitu sebanyak 78 mahasiswa. Hasil penelitian menunjukkan persiapan belajar yang dilakukan oleh mahasiswa dalam menghadapi post-test tidak berdampak signifikan terhadap kelulusan mereka berdasarkan standar nilai yang digunakan di jurusan kedokteran (α = 0.233). Kegiatan matrikulasi terbukti secara signifikan meningkatkan pengetahuan peserta, namun tidak cukup baik untuk mendapatkan predikat lulus berdasarkan sistem penilaian.
The Difference in Patient Characteristics based on Cervical Cancer Stage at Soedarso Hospital Fatinah, Nabilah Nurul; Pratiwi, Sari Eka; Trianto, Heru Fajar; Wahyudi, Tri; Rahmayanti, Sari
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 23, No 2 (2023): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v23i2.16961

Abstract

Cervical cancer ranks fourth-most in cancer mortality in women worldwide and second in incidence and mortality from cancer in women in Indonesia. Many cervical cancer patients are diagnosed at an advanced stage with a poor prognosis and increased mortality, so it is necessary to identify the characteristics related to the stage. This research aims to determine the differences in patient characteristics based on the cervical cancer stage. This study was analytical with a cross-sectional approach. Samples were taken using consecutive sampling techniques with a total sample of 99 people. The research was conducted at Soedarso Hospital Pontianak by collecting data from medical records and an anatomical pathology laboratory. Most cervical cancer patients in this study were 41-50 years of age (39,4%), were a housewife (78,8%), had graduated from elementary school (44,4%) and had a number parity of more than 5 (31,3%). The data were analyzed using the Kruskal-Wallis. Statistical tests showed a significant difference between age (p 0.000), occupation (p 0.003), and parity (p 0.017) to the cervical cancer stage. It indicated that older ages, more parity, and housewife tended to be diagnosed with an advanced stage of cervical cancer. This study implied that older women, more parity, and housewives should be more aware of cervical cancer risk.
Faktor yang Berhubungan dengan Kejadian Batuk Kering pada Pasien Hipertensi yang Menggunakan Obat ACE Inhibitor di Puskesmas Rahmaddani, Metta Sintia; Asseggaf, Syarifah Nurul Yanti Rizki Syahab; Rahmayanti, Sari
Jurnal Pharmascience Vol 11, No 2 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.18054

Abstract

Salah satu efek samping yang ditimbulkan oleh pasien yang mengonsumsi obat antihipertensi ACE Inhibitor adalah batuk kering. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan kejadian batuk kering pada pasien hipertensi yang menggunakan obat ACE Inhibitor di Puskesmas. Penelitian ini menggunakan desain analitik observasional dengan metode cross-sectional dan analisis data chi-square. Kriteria inklusi mencakup pasien hipertensi yang diberikan obat antihipertensi di Puskesmas, dengan total responden sebanyak 126 orang, di mana 63 orang di antaranya adalah pengguna ACE Inhibitor. Kejadian batuk kering di antara pengguna obat ACE Inhibitor tercatat pada 50 responden (39,7%), dengan nilai p sebesar 0,000. Faktor-faktor yang paling berhubungan dengan kejadian batuk kering adalah riwayat merokok dan lama penggunaan obat. Hasil penelitian menunjukkan beberapa faktor yang berkaitan dengan kejadian batuk kering pada pasien hipertensi yang menggunakan ACE Inhibitor di Puskesmas. Kata Kunci: Hipertensi, ACE Inhibitor, Batuk Kering, Efek Samping, Riwayat Merokok One of the side effects experienced by patients taking ACE Inhibitor antihypertensive medications is a dry cough. This study aims to identify the factors associated with the occurrence of dry cough in hypertensive patients using ACE Inhibitors at the community health center (Puskesmas). This research employed an analytical observational design with a cross-sectional method and chi-square data analysis. Inclusion criteria included hypertensive patients receiving antihypertensive medication at the Puskesmas, with a total of 126 respondents, of which 63 were ACE Inhibitor users. The occurrence of dry cough among ACE Inhibitor users was recorded in 50 respondents (39.7%), with a p-value of 0.000. The factors most associated with the occurrence of dry cough were a history of smoking and the duration of medication use. The study results indicate several factors related to the occurrence of dry cough in hypertensive patients using ACE Inhibitors at the Puskesmas.
Co-Authors Abdul Rashid, Ayu Akida Abror Irsan Akmal, Yudha Barri Andi Yasmon Andriani Andriani Armyanti, Ita Asseggaf, Syarifah Nurul Yanti Rizki Syahab Diana Natalia Diana Natalia Diana Natalia Diana Natalia Divis, Paul Cliff Simon Effiana Effiana Effiana, Effiana Fatinah, Nabilah Nurul Handoko, Willy Junita Indarti Lisnawati Rachmadi Mardhia, Mardhia Mardhia, Mardhia Mistika Zakiah Muhammad Ibnu Kahtan Muhammad In'am Ilmiawan Nawangsari, Nawangsari Nazaria, Riska Puji Astuti Puji Astuti Puspasari, Ratih Hemiarista Rahmaddani, Metta Sintia Riska Nazaria Sari Eka Pratiwi Syarifah Nurul Yanti Rizki Syahab Assegaf Taniyo, Nurul Fadhilah Tri Wahyudi Trianto, Heru Fajar Woris Christoper