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Analisis Perbandingan Kinerja Keuangan Perusahaan Sebelum Dan Setelah Kombinasi Bisnis (Studi Pada Perusahaan Yang Terdaftar Di Bursa Efek Indonesia) Ningsih, Nadya Ayu; Kurniawati, Tri
Jurnal Salingka Nagari Vol 3 No 2 (2024): Jurnal Salingka Nagari
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/jsn.v3i2.212

Abstract

This study aims to analyze and explain the differences in financial performance before and after business combinations in companies listed on the Indonesia Stock Exchange (IDX). The type of research used is quantitative research. The research technique is comparative statistics. The data source is secondary with a sampling method using Saturated Samples with a sample size of 40 samples. Data testing was conducted using the Paired T-Test and Wilcoxon Sign Rank Test calculated using Statistical Package Social Sciences (SPSS) 21 software. The results of the hypothesis test that had been conducted showed that there were 14 ratios that did not experience significant differences, namely Current Ratio (CR), Quick Ratio (QR), Cash Ratio (CsR), Cash Turnover Ratio (RPK), Inventory To Net Working Capital, Debt to Asset Ratio (DAR), Long Term Debt to Equity Ratio (LTDtER), Debt to Equity Ratio and Fixed Charge Coverage (FCC), Net Profit Margin, Gross Profit Margin, Return On Investment (ROI), Return On Equity (ROE) and Earnings Per Share (EPS). Meanwhile, the ratio that experienced a significant difference after the business combination was the Timed Interest Earned
HUBUNGAN KADAR TRANSFORMING GROWTH FACTOR BETA DENGAN DERAJAT NYERI PADA MIGRAIN DAN TENSION-TYPE HEADACHE Ningsih, Nadya Ayu; Surbakti, Khairul Putra; Pujiastuti, R. A. Dwi
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 1 (2025): Volume 42, No 1 - Desember 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v42i1.815

Abstract

ABSTRACT Introduction: Primary headaches, which mainly include Tension-type Headache (TTH) and migraine, account for 90% of all headaches and are the leading cause of disability worldwide. Migraine and TTH have pathogenesis that is not fully known, with one theory proposing neurogenic inflammation. Human Transforming Growth Factor β (TGF-β) is a pro-inflammatory cytokine that is thought to be involved in the occurrence of migraine and TTH. Objective: To determine the correlation between human TGF-β levels and the pain severity in migraine and TTH. Methods: This study used a cross-sectional design in patients with a diagnosis of migraine and TTH who sought treatment at the Ambulatory Clinic of Adam Malik Hospital and Prof. Dr. Chairuddin P. Lubis Hospital. We use Numeric Rating Scale score to determine the pain severity and ELISA kit to measure the TGF-β levels. This study involved 30 patients who met the inclusion and exclusion criteria. Results: The study subjects were found to be mostly female, 22 people (73.3%), with the age range of 18 to less than 26 years which was 20 people (66.7%). The mean TGF-β level of patients was 0.400±0.531 ng/mL. The mean pain severity of patients was 2.60±2.415. The results of the Spearman correlation test showed a moderate positive correlation (r: 0.523) which was found significant with a p value of 0.003 between TGF-β and the pain severity in migraine and TTH. Conclusion: There was significant correlation between human TGF-β levels and pain severity in migraine and TTH. Keywords: migraine, pain severity, TGF-β, TTH