Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Journal of Biomedicine and Translational Research Jurnal Prima Medika Sains
Rambe, Syahrul Ramadan
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Surgical hip dislocation for posterior hip dislocation with femoral head fracture pipkin classification type II: A case report Siregar, Chairiandi; Rambe, Syahrul Ramadan; Renaldi, Rizal
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.5664

Abstract

Introduction: Surgical hip dislocation is a powerful and safe approach. It allows for simultaneous treatment of intra-articular pathologies, either preexisting or as a result of trauma, and improves long-term results. It can be used to treat a wide variety of intra-articular pathologies that would be extremely challenging or impossible arthroscopically or with other common open approaches to the hip. Surgical hip dislocation has been used in the trauma setting for open reduction and internal fixation of femoral head fractures and posterior wall acetabular fractures that do not extend into the posterior column. Case Report: A 28-year-old male with a posterior hip dislocation had difficulty flexing and extending his hip, internal rotation, and shortening his leg. During physical examination, we found a prominent head left femur on the posterior gluteus. During an X-ray examination, we found a posterior dislocation of the femoral head with a fracture. Treatment: Open reduction is preferable whenever there is a nonconcentric hip reduction. This reduces the risk of additional trauma, thus avoiding abrasion to the articular cartilage and bone contusion at the head of the femur. The surgeon who performs open reduction must be fully familiar with the surgical anatomy of the hip and must be aware of the fixation techniques used on fractures in this region. The fragment can be fixed both with 2.0-mm Herbert screws or mini fragment screws, taking care of the head of the implant into the articular cartilage. The joint capsule should always be repaired. When femoral head impaction is present, and the patient is an adult, the goal is to save the femoral head. In this situation, it is preferable to use the Watson-Jones or anterolateral approach with greater trochanteric osteotomy to perform the controlled dislocation of the hip.
Effects of Vitamin C Supplementation on Histology of Callus Diameter and Osteoblast Number in Male Wistar Rats With Complete Femur Bone Fracture Rambe, Syahrul Ramadan; Putra, Reza Mahruzza; Rahmadhany, Heru
Journal of Biomedicine and Translational Research Vol 11, No 1 (2025): April 2025
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v11i1.25888

Abstract

Background: The role of nutritional factors, particularly vitamin C, in bone repair has been extensively studied. However, despite this research, the specific impact of vitamin C on bone fracture healing remains unclear. While some studies suggest that vitamin C supplementation may enhance bone repair, others report no significant benefits.Objective: This study aimed to investigate the effects of different doses of vitamin C on callus formation and osteoblast proliferation in a rat femur fracture model.Methods: A post-test-only control group design was employed in this study, involving 27 male Wistar rats that were randomly divided into three groups. The first and second groups received daily intramuscular injections of vitamin C at doses of 200 mg/kg body weight (BW) and 500 mg/kg BW, respectively, following femur bone fracture and fixation. The control group did not receive vitamin C and underwent no fixation. After 14 days, all rats were euthanized, and their femur bones were histologically examined for callus diameter and osteoblast count.Results: Vitamin C supplementation significantly increased the callus diameter in rats with complete femoral fractures. Both the 200 mg and 500 mg doses proved effective, demonstrating a clear dose-response relationship. Additionally, Vitamin C significantly elevated the number of osteoblasts, which play a crucial role in bone formation. However, there was no statistically significant difference in osteoblast count between the 200 mg and 500 mg doses.Conclusion: In conclusion, vitamin C supplementation has been shown to positively influence bone fracture healing in rats by promoting an increase in callus diameter and enhancing osteoblast proliferation. This study indicates that vitamin C could serve as a beneficial adjunct therapy for facilitating bone fracture healing, particularly by improving callus formation. Physicians should consider integrating vitamin C into treatment plans for patients with fractures, using doses similar to those applied in this study, adjusted appropriately for human use.
Co-Authors Putra, Reza Mahruzza Rahmadhany, Heru Renaldi, Rizal Siregar, Chairiandi