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All Journal Jurnal Pijar MIPA Takuana: Jurnal Pendidikan, Sains, dan Humaniora Journal of Pharmaceutical and Sciences.
Al Qindy, Wildan Hidayah
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Effect of Using Natural Liquid Soap on the Effectiveness of Staphylococcus Aureus Bacteria Control and Skin Health: A Review Al Qindy, Wildan Hidayah; Septiani, Dia
Jurnal Pijar Mipa Vol. 19 No. 6 (2024): November 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i6.7879

Abstract

The skin is a protective barrier against environmental disturbances and infections. Staphylococcus aureus is a common bacterium on human skin that can lead to infections. In light of this, the study investigates the effectiveness of natural liquid soaps in controlling Staphylococcus aureus while promoting overall skin health. The primary objective is to showcase the advantages of using natural ingredients in liquid soap formulations compared to synthetic chemicals. To achieve this, the researchers conducted a systematic literature review (SLR), utilizing reputable databases such as PubMed and Mendeley to gather relevant studies focused on natural liquid soaps. They carefully selected articles based on inclusion criteria established through the PICO framework, emphasizing the antibacterial effectiveness of these natural products against Staphylococcus aureus. The review encompassed ten high-quality studies, revealing that formulations containing natural extracts such as breadfruit leaf, cardamom, aloe vera, and honey exhibited significant antibacterial activity against Staphylococcus aureus. These natural ingredients offered effective bacterial control and provided additional benefits, including skin moisturization and reduced irritation, making them preferable to synthetic alternatives. This study introduces a novel perspective by comprehensively reviewing various natural ingredients used in liquid soaps and their comparative effectiveness against Staphylococcus aureus. It underscores the potential of plant extracts and essential oils as safer and more effective alternatives to traditional chemical antibacterial agents in skin cleansers. In conclusion, natural liquid soaps effectively reduce Staphylococcus aureus on the skin while maintaining skin health. Incorporating natural ingredients ensures antibacterial protection without the adverse effects commonly associated with chemical-based soaps, such as dryness or irritation, thereby advocating a shift towards more natural skincare options.
Analisis langkah jalan bulanan dan kalori yang dihasilkan pada pemahaman konsep energi dan metabolisme individu Al Qindy, Wildan Hidayah; Damaira, Jihan Yusra; Siregar, Siti Hajar Leni
Takuana: Jurnal Pendidikan, Sains, dan Humaniora Vol. 4 No. 2 (2025): Takuana (July-September)
Publisher : MAN 4 Kota Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56113/takuana.v4i2.143

Abstract

This study describes the association between the walking activity and then knowledge of energy concepts and metabolism in everyday life. This study utilized an embedded mixed methods design. Data on steps taken and calories consumed were recorded over a three month period (April-June 2025) using the Samsung Health application. The findings reveal fluctuations in physical activity, with particularly high levels occurring in May. The step count was shown to be positively associated with the calorie expenditure. Reflection revealed that the walks were a successful means of allowing the researchers to make sense of concepts of energy and metabolism. The present study finds that students can learn science during physical activity, and is a good method to narrow the theory and practice gap between the students’ life relation in the context of science learning gradually.
Evaluasi Bukti dari Uji Klinis tentang Interaksi Antibiotik dan Antasida: Suatu Tinjauan Sistematis Literatur Al Qindy, Wildan Hidayah; Nurdin, Fitri Oktaviani; Khaerunisa, Aulia; Putri, Meisya Diffa Amalia; Hilmi, Indah Laily; Putri, Mukarromah Dita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1093

Abstract

Drug interactions between antibiotics and antacids represent an important clinical issue that can affect therapeutic efficacy and increase the risk of treatment failure. The concurrent use of these drug classes frequently occurs in clinical practice, particularly in patients receiving antibiotic therapy who also present with gastrointestinal complaints. This systematic literature review aims to evaluate the clinical trial evidence regarding antibiotic–antacid interactions, focusing on pharmacokinetic and pharmacodynamic mechanisms, clinical implications, and current research limitations. Relevant articles were identified through PubMed, Google Scholar, and other scientific databases using standardized keywords. Literature selection followed the PRISMA guidelines to ensure the quality and relevance of included studies. The analysis revealed that antacids and proton pump inhibitors (PPIs) can significantly reduce the bioavailability of antibiotics, especially fluoroquinolones and tetracyclines, through chelation with metal ions and by increasing gastric pH, thereby impairing drug absorption. Concomitant use of antibiotics and PPIs was also associated with a higher risk of Clostridioides difficile infection (CDI), particularly in elderly or comorbid patients. Conversely, newer acid-suppressing agents such as vonoprazan demonstrated good efficacy in Helicobacter pylori eradication regimens without compromising antibiotic activity. Despite these findings, most studies were retrospective, with limited sample sizes and specific populations. Therefore, large-scale prospective clinical trials are needed to strengthen the evidence base. A comprehensive understanding of antibiotic–antacid interactions is essential to support rational, safe, and effective prescribing practices in clinical settings.
Co-Authors Damaira, Jihan Yusra Indah Laily Hilmi Khaerunisa, Aulia Nurdin, Fitri Oktaviani Putri, Meisya Diffa Amalia Putri, Mukarromah Dita Septiani, Dia Siregar, Siti Hajar Leni