Claim Missing Document
Check
Articles

Found 4 Documents
Search

Effect of Breadfruit Leaf (Artocarpus altilis) Extract on Histological Features of the Seminiferous Tubules in Diabetic Wistar Rats Wulandari, Puspa; NurCita, Boenga; Kristanti, Melly; Irsyad, Nasihin Saud
AL-MIKRAJ Jurnal Studi Islam dan Humaniora (E-ISSN 2745-4584) Vol 5 No 01 (2024): Al-Mikraj, Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6436

Abstract

Hyperglycemia can lead to increased free radicals formation that can potentially cause oxidative stress as a trigger for male reproductive organ damage, damaging the histological structure of seminiferous tubules as a place for sperm cell formation. Flavonoids in breadfruit (Artocarpus altilis) are known to be able to counteract free radicals caused by diabetes. The research was conducted to observe the effect of breadfruit leaf extract on the histological features of seminiferous tubules in diabetic Wistar rats. This true-experimental research with post-test-only control group design and purposive sampling technique to obtain 30 Wistar white male rats 8-12 weeks old weighing 150-200 g were grouped into 5 groups. The negative control group was fed standard food; the positive control was induced with STZ, and treatments 1, 2, and 3 were given the extract at doses of 200 mg/kgBW, 400 mg/kgBW, and 800 mg/kgBW consecutively for 30 days. Assessment of spermatogenesis in the histology of seminiferous tubule using Johnsen score criteria. Data were analyzed by the Kruskal-Wallis and the Mann-Whitney U posthoc test, which revealed significance with a p-value of <0.001 (<0.05). This study showed that breadfruit leaf extract can improve the histology of seminiferous tubules. Despite not being as good as the histology of seminiferous tubules under normal conditions, it has a therapeutic effect.
SOSIALISASI ANTI BULLYING : PENGEMBANGAN KARAKTER PESERTA DIDIK DI SMA NEGERI 6 KOTA BENGKULU Wulandari, Puspa
TRIBUTE: JOURNAL OF COMMUNITY SERVICES Vol. 6 No. 1 (2025)
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/tribute.v6i1.38677

Abstract

Maraknya kasus bullying di lingkungan sekolah menimbulkan keprihatinan terhadap kesehatan mental dan perkembangan peserta didik. Bullying, baik dalam bentuk fisik maupun non-fisik, memiliki dampak negatif yang serius, termasuk gangguan emosi, masalah mental, hingga penurunan prestasi akademik. Artikel ini memaparkan hasil kegiatan Sosialisasi Anti Bullying yang dilaksanakan di SMA Negeri 6 Kota Bengkulu sebagai bagian dari program Kuliah Kerja Nyata (KKN) Merdeka Belajar Kampus Merdeka (MBKM) Universitas Bengkulu. Metode yang digunakan meliputi ceramah, diskusi interaktif, dan evaluasi melalui kuis. Kegiatan ini bertujuan untuk meningkatkan pemahaman siswa mengenai definisi, jenis, penyebab, dampak, serta upaya pencegahan bullying. Hasil kegiatan menunjukkan bahwa sosialisasi ini berhasil memberikan pemahaman yang lebih baik kepada siswa, mendorong mereka untuk menciptakan lingkungan sekolah yang aman, serta memberikan panduan mengenai tindakan yang harus diambil jika menjadi korban atau menyaksikan kasus bullying. Kegiatan ini diharapkan dapat berkontribusi dalam menurunkan angka kasus bullying di sekolah.
Pengaruh Akses Sanitasi Layak, Kemiskinan dan Jumlah Penduduk Terhadap IKLH di Pulau Sumatera Tahun 2018-2022 Falatansya, Syafira; Sabrina, Sukma Amalia; Wulandari, Puspa; Permana, Elang; Purwoto, Agus
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 6 (2025): July 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15984260

Abstract

This study aims to analyze the influence of access to proper sanitation, poverty, and population on the Environmental Quality Index (IKLH) on Sumatra Island during the period 2018–2022. Environmental problems in this region are influenced by socio-economic and demographic factors, such as low access to sanitation, poverty levels, and uneven population growth. The study uses a quantitative approach with a Fixed Effect Model panel data regression model, selected based on the results of the Chow and Hausman test. Data used are sourced from the Central Statistics Agency (BPS), processed to produce a picture of fluctuations in the IKLH, sanitation access, poverty, and population in ten provinces on Sumatra Island. The results show that access to proper sanitation has a positive effect on the IKLH, while poverty and population have a negative effect. Aceh Province recorded the highest IKLH, while Lampung recorded the lowest, with variations influenced by infrastructure and welfare inequality. The output of this study is expected to form the basis for policies to improve environmental quality through improving sanitation access, poverty alleviation, and managing sustainable population growth.
Effect of Breadfruit Leaf (Artocarpus altilis) Extract on Histological Features of the Seminiferous Tubules in Diabetic Wistar Rats Wulandari, Puspa; NurCita, Boenga; Kristanti, Melly; Irsyad, Nasihin Saud
AL-MIKRAJ Jurnal Studi Islam dan Humaniora Vol. 5 No. 01 (2024): Al-Mikraj, Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6436

Abstract

Hyperglycemia can lead to increased free radicals formation that can potentially cause oxidative stress as a trigger for male reproductive organ damage, damaging the histological structure of seminiferous tubules as a place for sperm cell formation. Flavonoids in breadfruit (Artocarpus altilis) are known to be able to counteract free radicals caused by diabetes. The research was conducted to observe the effect of breadfruit leaf extract on the histological features of seminiferous tubules in diabetic Wistar rats. This true-experimental research with post-test-only control group design and purposive sampling technique to obtain 30 Wistar white male rats 8-12 weeks old weighing 150-200 g were grouped into 5 groups. The negative control group was fed standard food; the positive control was induced with STZ, and treatments 1, 2, and 3 were given the extract at doses of 200 mg/kgBW, 400 mg/kgBW, and 800 mg/kgBW consecutively for 30 days. Assessment of spermatogenesis in the histology of seminiferous tubule using Johnsen score criteria. Data were analyzed by the Kruskal-Wallis and the Mann-Whitney U posthoc test, which revealed significance with a p-value of <0.001 (<0.05). This study showed that breadfruit leaf extract can improve the histology of seminiferous tubules. Despite not being as good as the histology of seminiferous tubules under normal conditions, it has a therapeutic effect.