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All Journal Jurnal Sains Farmasi dan Kesehatan Jurnal Riset Multidisiplin Edukasi
Aura Nasyafa
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Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other

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Formulasi Dan Evaluasi Sedian Tablet Dengan Metode Kempa Langsung Aura Nasyafa; Novita Indira Sari; Lili Sa’adah; Nur Asyifa Ramadhanti; Tiara Maulida
Jurnal Sains Farmasi Dan Kesehatan Vol. 2 No. 2 (2024): September - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v2i2.1790

Abstract

The objective of this research is to study the formulation and evaluation of tablet preparations using the direct compression method. The method used in this research is a Systematic Literature Review. The findings of the study explain that the direct compression method is an efficient and economical technique in tablet production, especially in the pharmaceutical industry. With the advancement of technology, this method is increasingly used to produce tablets directly from a mixture of active ingredients and excipients without going through granulation processes, whether wet or dry. This process allows for time and cost savings in production, as well as reducing the use of machinery and labor. The main advantage of direct compression is its ability to produce tablets with better disintegration and dissolution times, especially for active ingredients sensitive to heat and moisture. The selection of the appropriate fillers and binders, such as modified starch, pregelatinized potato starch, and Avicel, significantly impacts the physical quality of the tablets, including hardness, friability, and flowability. Furthermore, the research results show that the correct formulation, both in terms of the composition of excipients and the concentration of binders, can improve the physical properties of the tablets and meet the desired quality standards. Therefore, while the direct compression method offers many advantages, it is important to continue exploring and optimizing formulations, both in terms of excipient selection and mixing ratios, to achieve tablets with the best quality that meet pharmaceutical needs and are accepted by consumers.
FORMULASI DAN EVALUASI STABILITAS TIGA SEDIAAN HERBAL CAIR: SIRUP POLIHERBAL, FOOT SANITIZER, DAN FACE SPRAY Dhiya Shoufi Sahaja; Aura Nasyafa; Nor Latifah
Jurnal Riset Multidisiplin Edukasi Vol. 2 No. 7 (2025): Jurnal Riset Multidisiplin Edukasi (Edisi Juli 2025)
Publisher : PT. Hasba Edukasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71282/jurmie.v2i7.615

Abstract

This study presents an in-depth review of three journals focusing on the formulation, evaluation, and stability of polyherbal syrup preparations containing extracts of Moringa oleifera (drumstick leaves), Curcuma longa (turmeric rhizome), and Zingiber officinale (ginger rhizome). The polyherbal syrup is known for its strong antioxidant activity, with potential benefits as an immunomodulator and protection against degenerative diseases. The primary study emphasized physical stability testing through accelerated stability studies at 40°C ± 2°C and 75% ± 5% relative humidity for three months, using three preservative variations: sodium benzoate, methylparaben, and propylparaben. Evaluation of organoleptic properties, pH, viscosity, and specific gravity revealed that all formulations maintained good physical stability throughout the testing period. The review also highlights the importance of standardizing herbal raw materials through organoleptic testing, moisture content, water-soluble extract, and ethanol-soluble extract measurements to ensure consistent product quality. The syrup production process involves aqueous extraction of the herbal materials, followed by formulation with additional ingredients such as palm sugar, tamarind, lime, and appropriate preservatives. Overall, the findings suggest that this polyherbal syrup has significant potential as a stable, safe, and effective phytopharmaceutical product, supporting the utilization of local natural resources for the development of competitive herbal medicines in the modern pharmaceutical market.
Co-Authors Dhiya Shoufi Sahaja Lili Sa’adah Nor Latifah Novita Indira Sari Nur Asyifa Ramadhanti Tiara Maulida