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Sanjiwani, Ni Made Sukma
Universitas Mahasaraswati Denpasar

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PENGUJIAN AKTIVITAS ANTIOKSIDAN SHATA DHAUTA GHRITA DENGAN PENCUCIAN MENGGUNAKAN INFUSED WATER DAUN KAYU MANIS BALI Sanjiwani, Ni Made Sukma; Wibawa, Agung Ari Chandra; Rahadi, I Wayan Surya; Mariati, Ni Putu Ayu Mirah; Vinanda, Ketut Adelia; Pradnyandari, I Gusti Ayu Agung Ratih
Akta Kimia Indonesia Vol 9, No 2 (2024)
Publisher : LPPM, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j25493736.v9i2.19950

Abstract

Shata Dhauta Ghrita (SDG) is a basic medicinal preparation for external use or cream. SDG originally had the definition of Ghrita washed a hundred times with water [14]. This study aims to make Shata Dhauta Ghrita with washing using greentea-scented cinnamon leaf infused water. Shata Dhauta Ghrita with washing using cinnamon leaf infused water with greentea aroma was analyzed for antioxidant activity and antioxidant testing optimization was carried out, namely looking for optimal conditions and results. In this study, infused water was made first, then butter, ghee and shata dhauta ghritanya were made, making shata dhauta ghritanya using washing with cinnamon leaf infused water and flavored with green tea. Testing antioxidant activity with DPPH method: Weighed 25 mg of sample dissolved with a little methanol p.a, then put into a 25 milliliter volumetric flask, the volume is sufficient to indicate the limit and homogenized (1000 µg/ml). 0.5 ml of filtrate was taken and 3.5 ml of 0.1 mM DPPH solution was added in the test tube. The test solution was allowed to stand for 30 minutes at room temperature and dark area then measured the absorbance at the maximum wavelength using UV-Vis spectrophotometer. The antioxidant activity test of shata dhauta ghrita has an IC50 value of 22,445.1 which means it has very strong antioxidant activity. This very strong antioxidant activity is because shata dhauta ghrita has active substances, namely flavonoids, because the washing uses cinnamon leaf infused water. Shata dhauta ghrita has an IC50 value of 22,445.1 which means it has very strong antioxidant activity.
PENGUJIAN pH, GUGUS FUNGSI DAN AKTIVITAS ANTIBAKTERI KRIM BERBAHAN VIRGIN COCONUT OIL (VCO) Sanjiwani, Ni Made Sukma; Wibawa, Agung Ari Chandra; Sudiarsa, I Wayan; Mirah Mariati, Ni Putu Ayu; Setya Cahyani, I Gusti Ayu Agung Dwita; Pramana, I Made Wisnu Yoga
Akta Kimia Indonesia Vol 10, No 1 (2025)
Publisher : LPPM, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j25493736.v10i1.22603

Abstract

This study aims to determine the pH, determine the functional groups and determine the diameter of the inhibition zone of cream made from VCO. In this study, cream was made with 2 formulations, formula 1 with 15% VCO concentration and formula 2 with 20% VCO concentration. In making the cream, all the ingredients that will be used were weighed first. The oil phase (VCO, vaselin album, stearic acid, span 60, and propyl paraben) was heated to 70°C. The water phase (glycerin, methyl paraben, tween 80, and distilled water) was heated to 70°C. The water phase was gradually incorporated into the oil phase at 70°C. It was then homogenised at 2000 rpm for 15 minutes to cool. Both cream formulas were analysed for pH, functional groups and antibacterial activity.                                  The pH of VCO-based cream in formula 1 has an average pH value of 5.91 and formula 2 has an average pH value of 6.03, so each cream sample has an acidity level with a range of 4.5-6.5. The functional groups found in VCO-based cream formulas 1 and 2 are: C-H bending, C=C stretch (aliphatic and aromatic); C=N, C=O stretch (acids, aldehydes, ketones, amides, esters, anhydrides), CΞC stretch; CΞN, C-H stretch: CH3; CH2, Stretch C-H: C-H; C=C-H; Ar-H. In the range of numbers 3750 - 3000 cm-1 there are functional groups O-H; N-H. Waves 3000-1000 cm-1 have a sharp band shape and strong intensity. The wavenumber 3700-3100 cm-1 has a wide band shape and strong intensity. F2 cream has a larger inhibition zone diameter than F1 cream. The diameter of the inhibition zone of cream F2 is largest at a concentration of 10%, the greater the concentration the less the diameter of the inhibition zone.