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All Journal Sasambo Journal of Pharmacy Analit: Analytical And Environmental Chemistry
Azri, Anna Sa'dia
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Chemistry Energy Environmental Science Health Professions Medicine & Pharmacology

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Analisis kualitatif bahan kimia obat dalam jamu pegal linu di wilayah kabupaten Grobogan Azri, Anna Sa'dia; Haresmita, Perdana Priya
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.341

Abstract

The use of traditional medicine in Indonesia, particularly jamu, remains very popular and an important part of the public health culture. According to the 2018 Riskesdas data, around 59.12% of the Indonesian population consumes jamu, and 95.6% of them recognize the health benefits obtained from it. Jamu, which is made from various types of plants, has been used for thousands of years to maintain health and treat various diseases. This study used Thin Layer Chromatography to identify Medicinal Chemicals (BKO) in jamu circulating in Grobogan Regency, Central Java. The purpose of this study was to analyze the content of medicinal chemicals in traditional herbal medicine. Six samples of jamu pegal linu were tested with Silica Gel 60 F254 stationary phase and different mobile phases for each standard. The results showed that all samples of jamu pegal linu tested did not contain the investigated BKOs, indicating product safety from this aspect.
Validation of Medicinal Chemicals Analysis Methods in Pegel Linu and Rheumatic Herbs using the TLC-UV-Visible Spectrophotometry method Haresmita, Perdana Priya; Wardani, Arief Kusuma; Ramadhani, Diva Laila; Bayuaji, Dwibara; Azri, Anna Sa'dia; Putri, Nindya Yunia; Nadia, Mayla Eka
Analit : Analytical and Environmental Chemistry Vol. 8, No. 02 October (2023) Analit: Analytical and Enviromental Chemistry
Publisher : Jurusan Kimia FMIPA Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/aec.v8i2.2023.p63-74

Abstract

Jamu is a traditional Indonesian medicine. Herbal medicine for rheumatism and “pegal linu” is one of the most widely consumed types of traditional medicinal products by the public, so it is a type of traditional medicinal preparation that is prone to the addition of chemical drugs (BKO). All types of traditional medicines are prohibited from containing isolated or synthetic chemicals with medicinal properties. Samples of rheumatism and “pegal linu” jamu were purchased from Grobogan, Central Java, and Gunungkidul, Yogyakarta. Two samples were purchased from Grobogan, while four samples were purchased from Gunungkidul. The standards used were mefenamic acid, phenylbutazone, and diclofenac sodium. Qualitative analysis was carried out using thin-layer chromatography and quantitative analysis using UV-visible spectrophotometry. Validation of the analytical method is carried out by setting four parameters: linearity, precision, limit of detection, and limit of quantitation. Information about the content of BKO in traditional medicines circulating in the Grobogan and Gunungkidul areas, as well as references to valid analytical methods, will greatly assist the government and academics in educating the public about the dangers of long-term consumption of traditional medicine with BKO. The results showed that three of the six samples contained BKO, and the analytical method was valid.
Co-Authors Bayuaji, Dwibara Nadia, Mayla Eka Perdana Priya Haresmita, Perdana Priya Putri, Nindya Yunia Ramadhani, Diva Laila Wardani, Arief Kusuma