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Description of Mother’s Knowledge and Adherence to Use of Helminthic Drugs in Kuwaluhan Village, Magelang Regency, Central Java Amanda, Shalma Risqi; Haresmita, Perdana Priya; Wardani, Arief Kusuma; Hadi, Ismanurrahman
Jurnal Ilmu Kesehatan Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i1.3626

Worm infection has become public health issue with the highest prevalence in children under the age of five and elementary school-aged children. The children have difficulty maintaining the hygienist, especially when they are playing. This study aims to describe the level of knowledge and mothers’ adherence to the use of helminthic drugs in Kuwaluhan Village, Magelang Regency. This research used a descriptive study with both a survey method and a cross-sectional approach. The purposive sampling technique was used, while the questionnaire was distributed to mothers with children under the age of five and elementary school-age children in Kuwaluhan Village RW 2, Magelang Regency, in December 2022. The results showed that the level of knowledge of mothers in Kuwaluhan Village RW 2, Magelang Regency, regarding the use of helminthic drugs out of a total of 74 mothers indicated that 33 respondents (44.59%) had good knowledge, 29 respondents (39.19%) had sufficient knowledge, and as many as 12 respondents (16.22%) had less knowledge. Meanwhile, at the adherence level, respondents were categorized as having high adherence by 1 respondent (1.35%), medium adherence by 73 respondents (98.65%), and low adherence by 0 respondents (0%). Based on these results, most of the mothers in Kuwaluhan RW 2, Magelang Regency have good knowledge and have a medium level of adherence to using helminthic drugs for children.

QUALITATIVE AND QUANTITATIVE ANALYSIS OF MEDICINAL CHEMICALS OF “ JAMU REMATIK DAN PEGAL LINU “ IN MAGELANG REGION Haresmita, Perdana Priya; Wardani, Arief Kusuma; Pradani, Missya Putri Kurnia; Permatasari, Lina
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3829

Jamu for rheumatism and "pegal linu" are two of the most commonly used traditional medicine products in the community, so it is a type of traditional medicine preparation that is prone to the addition of medicinal chemicals. Any type of medicinal chemical should not be added to herbal preparations. The purpose of this study was to determine is there any medicinal chemicals in traditional medicine samples for "pegal linu" and rheumatism in the Magelang area. The total number of samples used is nine. Thin layer chromatography was used to analyze medicinal chemicals in traditional medicine, and preliminary organoleptic test was performed. The next step is a quantitative analysis using the UV-Visible spectrophotometric method. Prednisone, mefenamic acid, and ibuprofen were used as standards. The stationary phase was silica gel 60 F254, and the mobile phase was ethyl acetate: chloroform (4:1) for the prednisone standard, chloroform:methanol (9:1) for the mefenamic acid standard, and chloroform:ethanol (8:1) for the ibuprofen standard. Thin layer chromatography analysis showed that three of the nine traditional medicine samples tested positive for prednisone, but none contained mefenamic acid or ibuprofen. Herbs A, D, and E contained prednisone in their samples. Prednisone concentrations in the three samples were 0,252%; 0.754%, and 2,005%, respectively.

Comprehensive In silico Analysis of Antibacterial Compounds in n-Hexane Fraction from Jeruju Leaf (Acanthus ilicifolius) Wardani, Arief Kusuma; Haresmita, Perdana Priya; Alda, Mahkota; Vaira, Tischa
Indonesian Journal of Chemical Research Vol 11 No 3 (2024): Edition for January 2024
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2024.11-ari

In an emergency, to identify the most promising Hesperidin, Kaempferol-3,4'-di-O-methyl ether (Ermanin); Myricetin-3-glucoside, Peonidine 3-(4’-arabinosylglucoside); Quercetin 3-(2G-rhamnosylrutinoside); and Rhamnetin 3-mannosyl-(1–2)-alloside as a lead compound from Jeruju to develop new drugs from flavonoid analog. The active compound's structure is derived from the PubChem database and improves the stability through ChemDraw v19. The Protein Data Bank website identified the protein macromolecule with PDB code 3VSL. Redocking was performed to ensure validation of 3VSL. The docking method was carried out using the IGEMDOCK software version v2.1. Also, the chimera-1.13.1 program is used to know the interaction profile. The web server pkCSM and Protox II online tool were used to determine the toxicity. 3,7,11,15-tetramethyl-2-hexadecen-1-ol is the juju leaf chemical with the most promise as an antibacterial and the one that shows the maximum binding affinity when taking into account toxicity.

Pengembangan Pengelolaan Usaha Penyulingan Minyak Sereh Melalui Pelatihan Budidaya, Teknik Penyulingan dan Hiliriasi Produk Sereh Wangi (Andropogon nardus L) Desa Tempursari Wardani, Arief Kusuma; Agusta, Herma Fanani; Hasani, Rofi Abul; Nofitriana, Risma; Permatasari, Sukma Putri; Listiyani, Oktavia
Jurnal Pengabdian kepada Masyarakat UBJ Vol. 7 No. 2 (2024): June - December 2024
Publisher : Lembaga Penelitian Pengabdian kepada Masyarakat dan Publikasi Universitas Bhayangkara Jakarta Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31599/0ge8mz70

Low human resources are the main reason the citronella oil refining business in Tempursari village, Candimulyo, Magelang, which started in 2021, has stopped producing citronella oil. The quality of lemongrass essential oil is an indicator of success in the distillation process. Lemongrass oil is said to be of quality if it has a high yield and complies with (SNI) 06-3593-1995. To increase the community's knowledge and skills, a series of outreach activities, cultivation training, distillation techniques, making citronella solid soap products and practice of managing a website as promotional media were carried out. The focus of this service involves the participation of the community who are members of the Association of Farmer Groups, the Women's Farmer Community and Karangtaruna of Tempursari Village, Candimulyo District, Magelang Regency. The results of increasing knowledge and skills include the percentage of pre- and post-test scores which show an increase in knowledge of citronella cultivation from 62.68% to 71.33% and post-harvest knowledge from 38.02% to 82.50%. The level of improvement in distilling skills was shown by an increase in yield from 0.1% to 0.8%, partner skills also increased because they succeeded in making citronella solid soap, and Karangtaruna was able to control the operations of the website www.atsiri-tempursari.com so that the latest information could be conveyed through the media digital.

Pengaruh Ekstraksi Bertingkat Terhadap Kadar Flavonoid Total Ekstrak Binahong (Anredera cordifolia (Ten) Steenis) Fitriyani, Nisa; Haresmita, Perdana Priya; Wardani, Arief Kusuma; Rawar, Ellsya Angeline
Jurnal Kimia Fullerene Vol 9 No 2 (2024): Fullerene Journal Of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37033/fjc.v9i2.652

Binahong ( Anredera cordifolia (Ten.) Steenis) merupakan tumbuhan yang memiliki banyak khasiat dan sering digunakan untuk mengobati berbagai macam penyakit. Salah satu kandungan senyawa yang terdapat dalam daun binahong adalah flavonoid yang berfungsi sebagai obat tradisional. Penelitian ini bertujuan untuk mengetahui pengaruh ekstraksi maserasi bertingkat terhadap kadar total flavonoid ekstrak binahong. Metode yang digunakan dalam penelitian ini adalah eksperimental. Daun binahong di ekstraksi secara maserasi bertingkat dengan menggunakan pelarut yang memiliki kepolaran berbeda. Pelarut yang digunakan terdiri atas pelarut n-heksana (nonpolar), etil asetat (semi polar), dan etanol 96% (polar). Analisis kualitatif pada penelitian ini menggunakan uji tabung dan analisis kuantitatif menggunakan metode spektrofotometri UV-Vis pada panjang gelombang maksimum 417,5 nm dengan pembanding standar rutin. Hasil analisis kualitatif ekstrak n-heksan, ekstrak etil asetat, dan ekstrak etanol 96% mengandung flavonoid positif. Berdasarkan pengujian kuantitatif diperoleh kadar flavonoid total ekstrak n-heksan, etil asetat, dan etanol 96% berturut-turut yakni sebesar 2,3102%; 3,6124%; dan 1,0264%. Hal ini menunjukkan bahwa penggunaan ekstraksi maserasi bertingkat memberikan pengaruh terhadap kadar total flavonoid yang dihasilkan pada masing-masing ekstrak.

Innovation in production and digital marketing of herbal medicine to enhance quality and sustainability of the Tirta Sari Herbal Group in Magelang Wardani, Arief Kusuma; Lestari, May Synta; AzZahra, Anindya Shafira; Yusriyyah, Aanisah
Community Empowerment Vol 10 No 3 (2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.6676

This activity aims to improve the quality of Tirta Sari herbal medicine products through innovations in production processes and digital marketing. Innovations include the use of appropriate technology, such as temperature control during production, and promoting products via Instagram. Temperature variation testing was conducted to extend product shelf life without altering taste. As a result, the fresh herbal medicine produced was more hygienic, with extended shelf life—3 days for beras kencur and 7 days for kunir asam. Additionally, partners gained a better understanding of the importance of hygiene and food safety. Digital marketing via Instagram has helped the products become more widely recognized and favored by the public.

Formulasi sabun padat dengan kandungan minyak atsiri Cymbopogon Nardus L. Agusta, Herma Fanani; Wardani, Arief Kusuma; Hidayatullah, Farizqi Ramadhan
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.12831

Soap is a self-care product that plays an important role in maintaining body hygiene. The development of the cosmetic industry encourages innovation in soap formulations, one of which uses natural ingredients such as essential oils. Citronella oil is an agribusiness sector commodity with a good market share and high competitiveness. This study aims to develop a solid soap formulation containing Cymbopogon Nardus L. essential oil, which is known to have antimicrobial and antioxidant properties. Soap was made using a mixture of Virgin Coconut Oil and palm oil, NaOH with the addition of Cymbopogon Nardus L. essential oil and distilled water with varying concentrations. The basic physical and chemical properties of soap, such as organoleptic, pH and foam stability were evaluated with good soap parameters based on SNI 3532:1994. Based on the test results on the four formulas with the three parameters carried out, it can be concluded that the addition of citronella essential oil to the tested formulas strengthens the organoleptic characteristics of good solid soap. All formulas have pH values in the range that are slightly less safe for the skin (pH 10-13) as bath soap with SNI criteria (pH 9-11) and foam stability that tends to decrease during the 28 days of testing and outside the range of solid soap foam stability of 60-70% required by SNI 3532: 1994.

Qualitative and quantitative analysis of prednisone chemical content in rheumatic herbs in Magelang Region Afifah, Riza Nur; Wardani, Arief Kusuma; Kusuma, Tiara Mega
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.358

Currently, there is a phenomenon that shows that many herbs consumed by the public contain medicinal chemicals (BKO). This study aims to identify the presence of BKO prednisone in rheumatic herbs and its levels. This study took five types of samples of rheumatic herbs in Magelang area with different brands, namely samples of herbs A, B, C, D and E, which are available in capsule and powder form. Identification of prednisone in rheumatic herbs was carried out using thin layer chromatography (TLC) method with silica gel GF254 as stationary phase and ethyl acetate: chloroform mixture (4:1) as mobile phase. Quantitative analysis was performed using UV-Vis spectrophotometry with a maximum wavelength of 238.5 nm. The rf value of prednisone standard 0.42 was obtained and quantitative analysis showed that the prednisone content in sample B in the first replication was 3.22%, in the second replication was 2.18%, in the third replication was 2.23%.

Description of Mother’s Knowledge and Adherence to Use of Helminthic Drugs in Kuwaluhan Village, Magelang Regency, Central Java Amanda, Shalma Risqi; Haresmita, Perdana Priya; Wardani, Arief Kusuma; Hadi, Ismanurrahman
Jurnal Ilmu Kesehatan Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i1.3626

Worm infection has become public health issue with the highest prevalence in children under the age of five and elementary school-aged children. The children have difficulty maintaining the hygienist, especially when they are playing. This study aims to describe the level of knowledge and mothers’ adherence to the use of helminthic drugs in Kuwaluhan Village, Magelang Regency. This research used a descriptive study with both a survey method and a cross-sectional approach. The purposive sampling technique was used, while the questionnaire was distributed to mothers with children under the age of five and elementary school-age children in Kuwaluhan Village RW 2, Magelang Regency, in December 2022. The results showed that the level of knowledge of mothers in Kuwaluhan Village RW 2, Magelang Regency, regarding the use of helminthic drugs out of a total of 74 mothers indicated that 33 respondents (44.59%) had good knowledge, 29 respondents (39.19%) had sufficient knowledge, and as many as 12 respondents (16.22%) had less knowledge. Meanwhile, at the adherence level, respondents were categorized as having high adherence by 1 respondent (1.35%), medium adherence by 73 respondents (98.65%), and low adherence by 0 respondents (0%). Based on these results, most of the mothers in Kuwaluhan RW 2, Magelang Regency have good knowledge and have a medium level of adherence to using helminthic drugs for children.

QUALITATIVE AND QUANTITATIVE ANALYSIS OF MEDICINAL CHEMICALS OF “ JAMU REMATIK DAN PEGAL LINU “ IN MAGELANG REGION Haresmita, Perdana Priya; Wardani, Arief Kusuma; Pradani, Missya Putri Kurnia; Permatasari, Lina
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3829

Jamu for rheumatism and "pegal linu" are two of the most commonly used traditional medicine products in the community, so it is a type of traditional medicine preparation that is prone to the addition of medicinal chemicals. Any type of medicinal chemical should not be added to herbal preparations. The purpose of this study was to determine is there any medicinal chemicals in traditional medicine samples for "pegal linu" and rheumatism in the Magelang area. The total number of samples used is nine. Thin layer chromatography was used to analyze medicinal chemicals in traditional medicine, and preliminary organoleptic test was performed. The next step is a quantitative analysis using the UV-Visible spectrophotometric method. Prednisone, mefenamic acid, and ibuprofen were used as standards. The stationary phase was silica gel 60 F254, and the mobile phase was ethyl acetate: chloroform (4:1) for the prednisone standard, chloroform:methanol (9:1) for the mefenamic acid standard, and chloroform:ethanol (8:1) for the ibuprofen standard. Thin layer chromatography analysis showed that three of the nine traditional medicine samples tested positive for prednisone, but none contained mefenamic acid or ibuprofen. Herbs A, D, and E contained prednisone in their samples. Prednisone concentrations in the three samples were 0,252%; 0.754%, and 2,005%, respectively.

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