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Phonetic Analysis of English Segmental Sounds Produced by The English Young Learners' Teachers Azizah, Nadya Nur; Musthafa, Bachrudin
ENGLISH FRANCA : Academic Journal of English Language and Education Vol. 8 No. 2 November (2024): ENGLISH FRANCA : Academic Journal of English Language and Education pr
Publisher : Institut Agama Islam Negeri (IAIN) Curup

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29240/ef.v8i2.10900

Abstract

Indonesian English learners undoubtedly encounter difficulties in articulating the authentic phonetic sounds of English. This occurs because specific English phonemes are absent in the learner's native language, leading to unnatural pronunciation. Consequently, the teacher's role is crucial in developing proficient language skills, particularly in pronunciation, among English language learners. Teachers' proficiency in English is expected to help students correct their errors. Researchers are presently analyzing the pronunciation skills of English teachers. This study employs descriptive method and two data collection instruments: interview and picture description task. This study aimed to identify specific sounds that are frequently unnatural in English segmental and to determine the factors contributing to the unnatural sounds produced by EYL teachers. The findings of this study showed; an in-depth phonetic analysis of the teachers' production in terms of place of articulation, manner of articulation as well as distinctive features for the production of English consonant sounds, and openness of the mouth, tongue elevation, position of tongue elevation, lips shapes, as well as length of vocalization for the production of English vowel sounds. This study also determined that mother tongue interference as the primary factor of the unnatural sound made by the teachers.
Molecular Docking Senyawa Fiscalin b, Isoleutherin, Eleutherol, Kaempferol, dan Luteolin pada Tumbuhan Physalis angulata Linn. sebagai Anti Kanker Lidah pada Protein MMP-9 Riani, Nadia Nanda; Saputro, Anjar Hermadi; Auli, Winni Nur; Azizah, Nadya Nur; Simorangkir, Nanda Lenny Yuniaty br; Hutabarat, Stefanny Herlin Natalya; Natalia, Dela
Indonesian Journal of Chemical Science Vol. 14 No. 3 (2025): Indonesian Journal of Chemical Science
Publisher : Prodi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcs.v14i3.25817

Abstract

Kanker lidah adalah jenis kanker rongga mulut yang agresif dengan angka kejadian dan kematian tinggi, terutama karena diagnosis terlambat dan terbatasnya pilihan terapi efektif. Protein Matrix Metalloproteinase-9 (MMP-9) berperan penting dalam invasi dan metastasis sel kanker lidah dengan kemampuan mendegradasi matriks ekstraseluler, sehingga memfasilitasi penyebaran kanker. Tanaman herbal ciplukan (Physalis angulata Linn.) mengandung senyawa aktif seperti Lutheolin, Isoleutherin, yang berpotensi sebagai agen antikanker. Penelitian ini mengevaluasi afinitas senyawa Isoleutherin, Luteolin, Fiscalin b, Eleutherol, Kaempferol terhadap protein MMP-9 menggunakan metode molecular docking. Hasil menunjukkan Isoeleutherin memiliki energi ikatan bebas terendah (-8,49 kkal/mol), lebih rendah dibandingkan senyawa lain seperti Fiscalin b (-7,74 kkal/mol), Eleutherol (-7,73 kkal/mol), Kaempferol (-7,47 kkal/mol), dan Luteolin (-8,07 kkal/mol). Isoeleutherin memiliki potensi sebagai antikanker lidah walaupun kemampuannya tidak lebih baik dari ligan alaminya.