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All Journal Jurnal Ilmu Kedokteran dan Kesehatan Magna Neurologica
Soedaly, Betty
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Comparison of Therapy Effects Between A Single Non-Steroidal Anti-Inflammatory Drug and The Combination with Muscle Relaxant on The Degree of Lower Back Pain Santo Fitriantoro; Soedaly, Betty
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1145

Abstract

Background: Lower back pain often results from poor ergonomic practice, characterized by localized discomfort between the costal border and lower gluteus folds, lasting more than one day. Possible factors contributing to this condition include age, gender, body mass index, ergonomics, load, work life, smoking habits, physical activity, or sports habits. Objective: This study aimed to examine the difference in therapy effects between a single non-steroidal anti-inflammatory drug (NSAID) (sodium diclofenac) and the combination of muscle relaxants (diazepam) against the severity of lower back pain. The degree of pain was assessed using the Alternative Method of Quantitative Pain Assessment (MAPKN) at HM Ryacudu Hospital, North Lampung. The sample consisted of 40 patients receiving medications at the Neurology Polyclinic. Methods: A quantitative method was used with a descriptive comparative approach. Results: The results showed that statistical analysis obtained a significance level of 0.737, indicating a normal data distribution. A paired sample t-test had a significance level of 0.000, which suggested a rejection of Ho and an acceptance of Ha. Conclusion: Based on the results, the combination therapy of NSAID (sodium diclofenac) and muscle relaxant (diazepam) was more effective in reducing lower back pain than using only an anti-inflammatory drug.
GAMBARAN LUARAN PASIEN STROKE ISKEMIK DENGAN LEUKOSITOSIS DAN LEUKOSIT NORMAL Fitriantoro, Santo; Soedaly, Betty
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 4 (2024): Volume 11 Nomor 4
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i4.13639

Abstract

Menurut  WHO  stroke  adalah  suatu  keadaan  dimana  ditemukan  tanda-tanda klinis  yang  berkembang  cepat  berupa  defisit  neurologik  fokal  dan  global,  yang dapat memberat  dan  berlangsung  selama  24  jam  atau  lebih  dan  atau  dapat menyebabkan  kematian, tanpa  adanya  penyebab  lain  yang  jelas  selain vascular. Penelitian  ini  bertujuan  untuk mengetahui  bagaimana  gambaran  luaran  pasien stroke  iskemik  dengan  leukositosis  dan leukosit  normal.  Metode  penelitian yang digunakan  dalam  penelitian  ini  adalah  metode penelitian  kohort.  Penelitian  ini dilakukan  di  RSUD  H.M  Ryacudu.  Subjek  pada  penelitian ini  yaitu  pasien  yang berobat  ke  RSUD  H.M  Ryacudu.  Sementara  sampel  penelitiannya adalah 80 orang  penderita  stroke  iskemik,  dengan  32  pasien  stroke  iskemik  dengan leukosit normal  dan  48  orang  pasien  stroke  iskemik  dengan  leukosit  tinggi atau leukositosis. Berdasarkan  hasil  dan  pembahasan  penelitian  maka  dapat disimpulkan  bahwa  stroke  iskemik dengan  leukositosis  lebih  beresiko  terhadap kematian  dari  pada  stroke  iskemik  dengan leukosit  normal.  Hal  ini  juga dibuktikan  dengan  uji  mann  whitney.  Melalui  uji  ini diperoleh  nilai  signifikansi sebesar 0,000. Nilai  signifikansi  tersebut  lebih  kecil  dari 0,05,  maka  Ha  diterima dan  Ho  ditolak.  Sehingga  dapat  disimpulkan  bahwa  terdapat perbedaan  antara pasien  stroke  iskemik  dengan  leukosit  normal  dan  pasien  stroke  iskemik dengan  leukositosis.
Co-Authors Fitriantoro, Santo Santo Fitriantoro