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All Journal PREPOTIF : Jurnal Kesehatan Masyarakat The International Journal of Medical Science and Health Research Jurnal Anestesi dan Terapi Intensif Udayana
Putu Agus Surya Panji
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Dentistry Health Professions Medicine & Pharmacology Nursing Physics Public Health Veterinary

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The Analysis Study of Effectiveness and Complication of Propofol for Anesthesia: A Comprehensive Systematic Review Juan Paul Christian Herman; Putu Agus Surya Panji
The International Journal of Medical Science and Health Research Vol. 7 No. 1 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/421x9s32

Abstract

Background: Propofol has become one of the most widely used anesthetic agents worldwide, known for its rapid onset and quick recovery profile. This systematic review aims to analyze propofol’s effectiveness and complications in anesthesia practice based on literature from the past decade. Methods: The study followed PRISMA 2020 guidelines, reviewing English-language publications from 2014 to 2024. Editorials, duplicate reviews from the same journal, and papers lacking a DOI were excluded. The literature search was conducted using PubMed, SagePub, SpringerLink, and Google Scholar. Result: A total of 2,172 articles were initially identified through online databases (PubMed, SagePub, SpringerLink, and Google Scholar). After three rounds of screening, eight relevant studies were selected for full-text analysis. Conclusion: Propofol is a versatile and effective anesthetic, improving procedural efficiency, reducing PONV, and enhancing cancer surgery survival. However, challenges like hypotension and immune suppression require attention. Further research is needed to refine its use, dosing, and long-term effects.
Albumin Use and Its Association with Nutritional Status in the Intensive Care Unit : A Narrative Review Putu Eka Nantha Kusuma; Jeremy Jonathan; Putu Agus Surya Panji
Jurnal Anestesiologi dan Terapi Intensif Vol. 1 No. 2 (2025): JATI Agustus 2025
Publisher : Udayana University and Indonesian Society of Anesthesiologists (PERDATIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JATI.2025.v01.i02.p08

Abstract

Introduction: Albumin is the major protein in blood plasma that plays a pivotal role in the regulation of oncotic pressure and nutritional status, particularly in critically ill patients. Hypoalbuminemia is frequently observed in ICU patients and is associated with increased morbidity and mortality. This narrative review aims to assess the role and efficacy of albumin supplementation, administered both orally and intravenously, in supporting the nutritional status and prognosis of critically ill patients. Methods: A literature search was conducted across the PubMed, Google Scholar, ScienceDirect, and ProQuest databases utilizing the keywords: "albumin", "critical illness", "nutrition", and "ICU". Articles included were those published within the last 10 years, available in English and Indonesian, and comprised review articles, clinical trials, and clinical practice guidelines. The selection process was performed through the screening of titles, abstracts, and subsequent full-text reviews. A total of 23 articles were included in this review. Results: The literature indicates that albumin supplementation contributes to hemodynamic stability, a reduction in nosocomial infections, and improved prognosis in patients with conditions such as sepsis, ARDS, hepatic and renal dysfunction, and in post-operative states. Supplementation with snakehead fish (Channa striata) extract has also been reported to increase albumin levels. Accurate nutritional assessment, using tools like the Nutrition Focused Physical Exam (NFPE), Subjective Global Assessment (SGA), and biomarkers such as Total Lymphocyte Count (TLC) and Neutrophil to Lymphocyte Ratio (NLR) are essential for determining the nutritional status of critically ill patients. Specific recommendations from the ESPEN consensus and various hepatology and nephrology associations exist concerning the application of albumin in specific clinical conditions. Conclusion: Albumin supplementation holds significant potential in supporting the nutritional status and improving the clinical outcomes of critically ill patients. Further studies are required to determine optimal protocols and the cost-effectiveness of albumin therapy in the critically ill patient population.
RENAL RESISTIVE INDEX (RRI) GUIDED BY ULTRASOUND (USG) AS A DIAGNOSTIC PREDICTOR OF ACUTE KIDNEY INJURY IN SEPSIS PATIENTS Satria Pinanditas S; Putu Agus Surya Panji; I Made Gede Widnyana; I Wayan Suranadi; Tjahya Aryasa EM; I Made Agus Kresna Sucandra; Made Wiryana; Tjokorda Gde Agung Senapathi
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i1.27245

Abstract

This study is an observational analytical study with a cross-sectional design conducted in the intensive care unit of RSUP Prof. Dr. I.G.N.G. Ngoerah from January 2024 until completion. The study population consisted of patients aged 18-65 years who met the criteria for sepsis diagnosis without chronic kidney disease. Data analysis was performed using SPSS version 26, including descriptive analysis, ROC curve, diagnostic test, and correlation analysis. The mean RRI at 0 hours was ±SB 0.78±0.68 cm/s for the AKI group and ±SB 0.60±0.08 cm/s for the non-AKI group. The mean RRI at 6 hours was ±SB 0.77±0.65 cm/s for the AKI group and ±SB 0.60±0.08 cm/s for the non-AKI group. The cut-off point for RRI at 0 hours was ?0.70 cm/s, with a sensitivity of 84.6%, specificity of 88.9%, accuracy of 86.4%, PPV of 91.7%, and NPV of 80%, with a relative risk of AKI of 4.58 times (95% CI 1.89-11.10; P<0.001). Meanwhile, for RRI at 6 hours, the cut-off point was also ?0.70 cm/s, with a sensitivity of 88.5%, specificity of 88.9%, accuracy of 88.6%, PPV of 92%, NPV of 84.2%, and a relative risk of AKI of 5.83 times (95% CI 2.05-16.56; P<0.001). The correlation coefficient between RRI at 0 hours and serum creatinine was r=0.380, p=0.011, while for RRI at 6 hours, it was r=0.393, p=0.008. RRI at 0 hours showed a correlation with urine production with r=-0.428, p=0.004, while for RRI at 6 hours, it was r=-0.540, p<0.001. In conclusion, RRI guided by ultrasound is a good diagnostic predictor for acute kidney injury in sepsis.
Co-Authors I Made Agus Kresna Sucandra I Made Gede Widnyana I Wayan Suranadi Jeremy Jonathan Juan Paul Christian Herman Made Wiryana Putu Eka Nantha Kusuma Satria Pinanditas S Tjahya Aryasa Tjokorda Gde Agung Senapathi