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PERBANDINGAN EFEKTIVITAS CEFTRIAXONE DAN CEFOTAXIME PADA PASIEN ANAK DEMAM TIFOID DI RUMAH SAKIT MITRA SIAGA Rosaria Ika Pratiwi; Anggy Rima Putri
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.461

Abstract

Ceftriaxone and cefotaxime are the antibiotics of choice for the treatment of typhoid fever. The effectiveness of antibiotics can be seen based on the length of stay in the hospital. This study aims to determine the characteristics of children with typhoid fever and the comparison of the effectiveness of ceftriaxone and cefotaxime on the length of stay in children with typhoid fever at Mitra Siaga hospital. The study was an observational analytic study with a sample of 100 medical records for children with typhoid fever who had met the inclusion and exclusion criteria. The effectiveness analysis was processed using the Mann-Whitney method. The results showed that the characteristics of the children with typhoid fever were 43% female (43 people) and 57% male (57 people), 52% (52 people) patients aged 1-7 years, and 48% (48 people). aged 8-14 years, length of stay 2 days 5% (5 people), 3 days 48% (48 people), 4 days 37% (37 people), 5 days 6% (6 people), 6 days 2% (2 person), 7 days 1% (1 person), and 8 days 1% (1 person). There was no difference in the effectiveness of ceftriaxone and cefotaxime on length of stay in patients with typhoid fever at Mitra Siaga hospital (P = 0.997> 0.05).
UJI AKTIVITAS ANTIBAKTERI HANDWASH EKSTRAK DAUN TURI (Sesbania grandiflora L) TERHADAP Staphylococus aureus Inur Tivani; Wilda Amananti; Anggy Rima Putri
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.426

Abstract

The corona virus which infects humans in almost all corners of the world changes new habits in human life. One of the highly recommended habits is washing your hands with soap. Turi leaves have active substances such as flavonoid compounds and saponins which can be used for making handwash. The purpose of this study was to determine the effectiveness of liquid soap (handwash) from turi leaf extract against Staphylocous aureus bacteria. This research was conducted in the microbiology laboratory of the Harapan Bersama Tegal Polytechnic. Turi leaves were extracted using the maceration method with 95% ethanol solvent, then the extract was made by hand washing soap with 3 formulas. The three formulas were then tested on S. aureus bacteria using the well diffusion method with three replications. The results of this study indicate that formula 1 has a diameter of inhibition of 13.72 ± 0.57mm, formula 2 is 16.36 ± 0.58 mm and formula 3 is 20.36 ± 1.13 mm. Thus it can be concluded that the liquid soap of formula 3 turi leaf extract is the best in inhibiting S.aureus bacteria.