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All Journal Padjadjaran Journal of Dentistry Indonesian Journal of Dentistry
Mahardika, Christina
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Effect coffee administration on alkaline phosphatase levels during relapse following orthodontic retention in rats: an experimental study Tyas, Septa Yumnaning; Abdurrohman, Muhamat Muhtar S; Mahardika, Christina; Yusuf, Moh
Padjadjaran Journal of Dentistry Vol 36, No 3 (2024): November 2024
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no3.57868

Abstract

Introduction: Maintaining teeth in their corrected positions following orthodontic treatment can be extremely challenging. Coffee is one substance whose effects on relapse have been extensively studied. The aim of study is to analyze the effect of coffee administration on relapse after orthodontic retention by evaluating alkaline phosphatase levels. Methods: This experimental laboratory study enrolled SpraqueDawley rats, with brackets applied using Edgewise slot 0.022” system and a nickel-titanium open coil spring fixed between the lower central incisors for 14 days. Based on Federer’s formula, 36 SpraqueDawley rats were randomly divided by simple random sampling into four groups: Group 1 (no retention), Group 2(retention for 3 days), Group 3(retention for 7 days), and Group 4(retention for 2 weeks). The Spraque-Dawley rats in the four experimental groups were given aquadest, 50 mg, and 100 mg/kg coffee intake ad libitum. Orthodontic relapse was assessed by measuring changes in alkaline phosphatase levels between the lower central incisors (the relapse side). Changes in the distance between the central incisors during relapse were observed visually. Alkaline phosphatase levels, which serve as a predictor of recurrence, were determined using an enzyme-linked immunosorbent assay (ELISA). Data analysis was conducted with the Two-way analysis of variance (ANOVA) and a post hoc Tukey test. Results: Overall, we found that a longer retention period was associated with a slower rate of relapse and a shorter overall amount of relapse. In addition, inhibiting osteoclast formation using coffee also reduced orthodontic relapse. Alkaline phosphatase (ALP) and/or its biomarkers could serve as potential therapeutic targets in the prevention and treatment of orthodontic relapse, with changes observed at a value of 0.001. This demonstrates that coffee administration affects alkaline phosphatase levels during relapse after orthodontic retention. Conclusion: Coffee administration increased alkaline phosphatase levels during relapse after orthodontic retention in rats.
ROOT CANAL TREATMENT IN CASE IRREVERSIBLE PULPITIS MAXILLARY PREMOLAR TEETH WITH DIRECT COMPOSITE: CASE REPORT Mahardika, Christina; Melati, Viona Sekar
Indonesian Journal of Dentistry Vol 5, No 2 (2025): August 2025
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/ijd.v5i2.17236

Abstract

Background: Irreversible pulpitis is an inflammatory process in the tooth that involves the pulp. Teeth that experience inflammation in the pulp require root canal treatment to eliminate bacteria. Post root canal treatment teeth with minimal loss of healthy tissue can be restored with direct composite. The purpose of this case report is to convey the success of multiple root canal treatment in cases of irreversible pulpitis with direct restoration. Case: A 47-year-old female patient came to RSGM Unimus, complaining of frequent toothache when eating cold food and in the morning. Intraoral examination showed blackness on the cervical of tooth 14 with positive sondation. Radiographic examination showed radiolucency on the cervical buccal of tooth 14 with pulp depth.Conclusion: The treatment performed showed good results, with root canal treatment in cases of irreversible pulpitis and direct restoration, so that it can maintain teeth, prevent further infection, provide good aesthetics and provide satisfaction to patients.
Co-Authors Abdurrohman, Muhamat Muhtar S Melati, Viona Sekar Moh Yusuf, Moh Tyas, Septa Yumnaning