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All Journal Indonesian Journal of Cancer Acta Neurologica Indonesia
Madjid, Irma Savitri
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Educating General Practitioners about Medication-overuse Headache: Importance and Call to Action Sofyan, Henry Riyanto; Madjid, Irma Savitri; Faiq, Ahmad Rafi; Indrapriambada, Ery Riady; Humaira, Sarah; Aninditha, Tiara
Acta Neurologica Indonesia Vol. 3 No. 01 (2025): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v3i01.49

Abstract

Medication overuse headache (MOH) is a secondary headache that frequently accompanied chronic primary headaches which poses a great burden in an individual and systemic level. Globally, it is recognized as one of the relevant headaches for primary care. However, in Indonesia, it has not been included in the standard competence for doctors, and therefore has been underrecognized by general practitioners who encountered headache patients in primary care. In this policy brief, we mapped the problems regarding MOH and proposed several action plans, including educating GPs, as the recommendations.
Headache Characteristic in Brain Tumor Patients Sembiring, Saulina; Sofyan, Henry Riyanto; Madjid, Irma Savitri; Alvonsius Silalahi, Raymond Aris Nimrod; Albertin, Elizabeth; Aninditha, Tiara
Indonesian Journal of Cancer Vol 19, No 1 (2025): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i1.1197

Abstract

Background: Headache is an alarm for structural abnormalities, and it frequently manifests as an initial symptom of brain tumors, with an occurrence rate ranging between 36-80%, depending on the type and location of the tumorMethods: We conducted a retrospective cross-sectional study to observe hospitalized brain tumor patients at Dr. Cipto Mangunkusumo Hospital from January 2022 to March 2023. This study described the prevalence and the percentages of baseline characteristics.Results: Our study revealed that out of 101 brain tumor patients, predominated by females (60.4%) with a mean age of 46.2 years. Secondary brain tumors originating from breast cancer were more prevalent (13.9%). Frontal lobe location was frequent (32.3%), displaying rapid growth (66.3%), focal deficits (82.2%), and headaches (79.2%). Atypical headache was the most common phenotype (40%), often occurring either before the onset of neurological deficits (prechronous) or concurrently with them (synchronous). Discussion: The study revealed that high-grade, rapidly growing brain tumors tend to induce focal neurological deficits and headaches due to the tumor’s progressivity and mass effect. Brain tumor lesions were primarily found in the frontal lobe of the supratentorial region, displaying a mainly atypical headache phenotype. The absence of pain receptors in the parenchyma suggested that pain resulted from mechanical stimulation of other pain-sensitive structures.Conclusion: Atypical headaches occurring within 30 days before neurological deficits could indicate potential malignancy.
Co-Authors Albertin, Elizabeth Alvonsius Silalahi, Raymond Aris Nimrod Aninditha, Tiara Faiq, Ahmad Rafi Humaira, Sarah Indrapriambada, Ery Riady Sembiring, Saulina Sofyan, Henry Riyanto