Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal BIOMA : Jurnal Biologi Makassar JURNAL KESEHATAN PERINTIS
Verdian Putra, Fuji
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Pemberian Ekstrak Asam Kandis terhadap Penurunan Glukosa Darah pada Tikus yang Diinduksi Aloksan sari, Rita permata; Diki Juliandi, Muhammad; Verdian Putra, Fuji; Endra Pratama, Yudha; Sintia Angraini, Dinda
JURNAL KESEHATAN PERINTIS Vol 11 No 2 (2024): Jurnal Kesehatan Perintis
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33653/jkp.v11i2.1113

Abstract

Diabetes mellitus merupakan penyakit metabolik yang ditandai dengan hiperglikemia kronis akibat gangguan sekresi insulin, kerja insulin, atau keduanya. Penggunaan bahan alami sebagai alternatif pengobatan diabetes semakin menarik perhatian, salah satunya adalah ekstrak etil asetat buah asam kandis Garcinia parvifolia (Miq.) Miq), yang diketahui memiliki kandungan bioaktif dengan potensi antidiabetes. Penelitian ini bertujuan untuk mengevaluasi efek pemberian ekstrak Asam Kandis terhadap penurunan kadar glukosa darah pada tikus yang diinduksi aloksan. Dalam penelitian ini, tikus jantan Wistar dibagi menjadi lima kelompok: kelompok kontrol negative (pemberian pakan standar, kontrol positif (diabetes yang diinduksi aloksan tanpa perlakuan), dan tiga kelompok perlakuan yang menerima dosis berbeda dari ekstrak Asam Kandis (40 mg, 80 mg dan 160mg). Kadar glukosa darah diukur menggunakan glukometer pada hari ke-0 (sebelum induksi aloksan), hari ke-7 setelah pemberian aloksan, dan pada hari ke-14, setelah pemberian ekstrak. Hasil penelitian menunjukkan bahwa pemberian ekstrak Asam Kandis dapat menurunkan kadar glukosa darah pada tikus yang diinduksi aloksan dibandingkan dengan kelompok kontrol positif. Efek penurunan glukosa darah terlihat lebih signifikan pada dosis rendah (40 mg) yang diberikan. Kesimpulan dari penelitian ini adalah ekstrak Asam Kandis memiliki potensi sebagai agen antidiabetes yang efektif dalam menurunkan kadar glukosa darah.
PENGARUH KONSENTRASI ASAM NITRAT SEBAGAI REAGEN DEKALSIFIKASI TERHADAP KUALITAS PEWARNAAN SAFRANIN O PADA TULANG Yusdarfadri, Rita Permatasari; Verdian Putra, Fuji
BIOMA : JURNAL BIOLOGI MAKASSAR Vol. 10 No. 2 (2025): Bioma : Juli - Desember 2025
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In histotechnology, bones play a certain role in the diagnosis of disease. The dilemma experienced by an anatomical pathology laboratory technician in making bone preparations or preparations containing high calcium salts. To overcome the hardness of the tissue due to the presence of calcium salts, a special technique called decalcification is needed. Strong acids such as hydrochloric or nitric acid are the fastest decalcification solutions in the decalcification process. Safranin is a cationic dye used in histology and cytology to differentiate and identify various tissues and cells. This study aims to determine the effect of nitric acid concentration as a decalcification reagent on the quality of safranin O staining in bones. This study uses an experimental method. The samples used in this study were beef ribs, then the specimens were decalcified with 5%, 10% and 15% nitric acid. The results showed that the nitric acid decalcification agent at concentrations of 5% and 10% obtained a consistency result of 1, meaning that the consistency of the beef rib bone sample was not soft, while 15% Nitric Acid obtained a consistency result of 3, meaning that the consistency of the beef rib bone sample was soft. Then, in the histological assessment of bone tissue preparations that have been stained with Safranin O, it was obtained at a concentration of 5% staining intensity with a final score grade of 0, meaning poor quality. At a concentration of 10% staining intensity with a final score of 1, meaning poor quality, and histological assessment of a concentration of 15% staining intensity with a final score of 2, meaning good quality. From this study, it can be concluded that the results of safranin O staining on beef ribs show differences in staining quality at different concentrations of decalsifying agents.
Co-Authors Diki Juliandi, Muhammad Endra Pratama, Yudha Sari, Rita Permata Sintia Angraini, Dinda Yusdarfadri, Rita Permatasari