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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Keperawatan Muhammadiyah
Aziz, Nahdah Aulia
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Health Professions Medicine & Pharmacology Nursing

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Analysis of Neutrophil, Leukocyte, Lymphocyte, and NLR Cell Profiles in Patients Diagnosed with Chronic Gastritis Affected by Helicobacter pylori and Non-Helicobacter pylori Infection at Dr. Soetomo Hospital in Surabaya, Indonesia Aziz, Nahdah Aulia; Wahyunitisari, Manik Retno; Susilo, Imam
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.21260

Abstract

Helicobacter pylori (HP) is a prevalent cause of bacterial infections, particularly chronic gastritis in the human body. The diagnosis of gastritis relied on gastric biopsy examination, where inflammation is characterized by an increase in various inflammatory cells, including macrophage, neutrophil, lymphocyte, or plasma cells. Therefore, this research aimed to determine the profiles of neutrophil, leukocyte, lymphocyte, and neutrophil lymphocyte ratio (NLR) in chronic gastritis patients, distinguishing between those with Helicobacter pylori and non-Helicobacter pylori infection at Dr. Soetomo Hospital in Surabaya. This research adopted a retrospective method, using medical records for chronic gastritis patients at Dr. Soetomo Hospital between 2018 and 2022. The variables analyzed included Helicobacter pylori infections and values of neutrophil, leukocyte, lymphocyte, and NLR cells. The obtained data were subjected to analysis using descriptive statistics. The results showed that the majority of participants were females (61.9%), senior high school graduates (52.38%), and aged 45-59 (pre-elderly) (32.14%). In non-Helicobacter pylori group, the average values of neutrophil, leukocyte, lymphocyte, and NLR cells were 62.29 (SD = 12.17), 8.155 (SD = 4.02), 29.165 (SD = 12.31), and 3.68 (SD=4.865), respectively. In conclusion, females showed a propensity for chronic gastritis with Helicobacter pylori. It was observed that non-Helicobacter pylori chronic gastritis tended to have elevated neutrophil and leukocyte values. Meanwhile, Helicobacter pylori-related chronic gastritis tended to show increased lymphocyte and NLR values due to systemic inflammation. Helicobacter pylori was associated with conditions such as iron deficiency anemia, cardiovascular disease, diabetes, thyroid disease, and malnutrition.
Effects of Yoga on Depression and Anxiety in Patients with Musculoskeletal Disorders: A Systematic Review and Meta-Analysis Uliyah, Musrifatul; Hidayat, Abdul Aziz Alimul; Aziz, Nahdah Aulia
Jurnal Keperawatan Muhammadiyah Vol 10 No 4 (2025): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

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Abstract

Background:Musculoskeletal disorders (MSDs) are a major cause of disability and are often accompanied by depression and anxiety, which may worsen pain and limit rehabilitation outcomes. Yoga, as a mind–body intervention, may provide both physical and psychological benefits; however, evidence regarding its effectiveness in MSD populations remains inconsistent. Methods:This systematic review and meta-analysis followed the PRISMA 2020 guidelines. Randomized controlled trials evaluating the effects of yoga on depression and/or anxiety in adults with musculoskeletal disorders were identified from PubMed/MEDLINE, Scopus, Cochrane Library, and CINAHL (January 2012–December 2025). A random-effects model was applied, and effect sizes were reported as mean differences or standardized mean differences with 95% confidence intervals. Risk of bias was assessed using the Cochrane Risk of Bias Tool. Results:Ten RCTs involving 1.063 participants were included. Yoga significantly improved depressive symptoms compared with control groups (MD = 1.19; 95% CI: 0.26–2.13; p = 0.01; I² = 61%) and significantly reduced anxiety (MD = 4.09; 95% CI: 0.64–7.54; p = 0.02; I² = 96%). Overall study quality ranged from low to moderate, mainly due to limited blinding. Conclusions:Yoga is associated with significant reductions in depression and anxiety among patients with musculoskeletal disorders. Despite substantial heterogeneity, yoga may be considered a complementary intervention within holistic musculoskeletal rehabilitation. Further high-quality trials with standardized protocols are required.
Co-Authors Imam Susilo Musrifatul Uliyah Wahyunitisari, Manik Retno