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Ikeh, Tri Sulapmi D.
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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P Penetapan Kadar Flavonoid Total dan Nilai Sun Protection Factor (SPF) Fraksi Ekstrak Etanol Daun Sirih Muda (Piper betle L.) Deviani, Norma; Hakim, Ali Rakhman; Ikeh, Tri Sulapmi D.; Nastiti, Kunti
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 1 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i1.617

Abstract

Background: Betel leaf (Piper betle L.) is a plant that contains many important secondary metabolite compounds, one of which is the flavonoid group. empirically in the community, especially in South Kalimantan, who use these leaves as a mixture of cold powder using young betel leaves as protection against sunlight.Objective: To determine the total flavonoid content of the young betel leaf extract fraction (Piper betle L.) and the sun protection factor (SPF) value in the distilled water and ethyl acetate fractions.Methods: The experimental method with a posttest-only control group design involved qualitative analysis using thin layer chromatography (TLC) and quantitative data using UV-Vis spectrophotometry to determine total flavonoid levels and sun protection factor (SPF) values using the Mansur method.Results: The TLC analysis confirmed the presence of flavonoid compounds. Quantitative analysis using UV-Vis spectrophotometry showed total flavonoid content of 14.4 mg EQ/g (1.44%) in distilled water and 16.4 mg EQ/g (1.64%) in the ethyl acetate fraction. The highest SPF value was 17.29 at 600 ppm in the ethyl acetate fraction (ultra protection), while the lowest was in the distilled water fraction at 200 ppm (minimum category).Conclusion: The young betel leaf extract fractions showed that the distilled water fraction contained 14.4 mg EQ/g (1.44%) flavonoids, while the ethyl acetate fraction had 16.4 mg EQ/g (1.64%). The highest SPF value of 17.29 (ultra protection) was found in the ethyl acetate fraction at 600 ppm.
C Cost Minimization Analysis (CMA) Penggunaan Obat Amlodipine Dan Captopril Pada Pasien Hipertensi di RSUD Sultan Suriansyah Banjarmasin Azizah, Siti; Yuwindry, Iwan; Ikeh, Tri Sulapmi D.; Melviani, Melviani
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 1 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i1.660

Abstract

Background: Hypertension is one of the serious problems currently known as the silent killer, and the prevalence throughout the world of hypertension is very high, which has the potential to increase the medical costs that must be borne by patients, therefore minimal treatment of hypertension can reduce the high incidence of hypertension.Objective: The aim of this study was to determine the most cost-minimum costs of using the drugs amlodipine and captopril in hypertensive patients in the outpatient installation of Sultan Suriansyah Hospital, Banjarmasin.Methods: This research was conducted using an observational analytical method with a cross sectional design. Data collection was carried out using medical records and details of drug costs in the pharmacy department, and receipts in the finance department for hypertensive patients in outpatient installations who received amlodipine and captopril treatment at Sultan Suriansyah Hospital, Banjarmasin. The sample used was 38 patients. The cost components collected are direct medical costs including the total costs for antihypertensive treatment, costs for treating comorbidities, administration costs and consultation costs.Results: The results of this research showed that the average total direct medical costs for the amlodipine group were Rp.98.491 and the captopril group was Rp.109.613.Conclusion: Based on cost minimization analysis calculations, the 2 antihypertensive drug therapies that are cost minimized are amlodipine 10 mg tablets compared to captopril 25 mg tablets.  
Co-Authors Ali Rakhman Hakim Deviani, Norma Melviani, Melviani Nastiti, Kunti Siti Azizah Yuwindry, Iwan