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All Journal Jurnal Mahasiswa Ilmu Kesehatan Nian Tana Sikka: Jurnal Ilmiah Mahasiswa
Juwita Ramadhani Octavianingrum
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Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health Social Sciences

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Peran Hormon Kortikosteroid dalam Regulasi Metabolisme dan Respons Stres pada Manusia Devina Adira Azzahra; Septi Puspita Kurniawati; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Nian Tana Sikka : Jurnal ilmiah Mahasiswa Vol. 3 No. 2 (2025): Nian Tana Sikka : Jurnal ilmiah Mahasiswa
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/niantanasikka.v3i2.733

Abstract

Corticosteroid hormones play a vital role in maintaining human homeostasis by regulating energy metabolism and stress responses. Glucocorticoids, such as cortisol, and mineralocorticoids, such as aldosterone, have specific functions in metabolic processes and electrolyte balance. Activation of the hypothalamic-pituitary-adrenal (HPA) axis during stress responses triggers corticosteroid release, enabling the body to cope with physical and psychological challenges. However, corticosteroid dysregulation can lead to various clinical disorders, such as Cushing's syndrome and Addison's disease, impacting metabolism and overall health. Furthermore, while corticosteroids are widely used in treating inflammatory and autoimmune diseases, prolonged use can cause severe side effects. This article aims to review the mechanisms, physiological roles, pathological impacts, and therapeutic potentials of corticosteroid hormones. The findings highlight the importance of managing these hormones in clinical conditions and the opportunities for developing more targeted and safer therapies.
Pentingnya Mengetahui Golongan Darah Anda: Dampaknya pada Kesehatan dan Kehidupan Sehari-hari Tyara Avrilyanti Ghea Indriansyah; Karina Sella Juwitasari; Margaretha Alesandria Natasya Weka; Pramesti Listanto; Latifa Alya Khairunnisa; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.2947

Abstract

Knowledge of one’s blood type plays a crucial role in supporting individual health and preparedness in medical emergencies. This literature review explores the relationship between the ABO and Rhesus blood group systems and various health outcomes, including susceptibility to infections, cardiovascular risks, and biochemical implications in personalized medicine. Based on a synthesis of ten scholarly sources, the findings reveal that blood type influences vulnerability to COVID-19, gastrointestinal infections, and elevates cardiovascular disease risk particularly among non-O blood types. These results emphasize the importance of early education and blood type screening as preventive measures. The study also highlights the need for integrating blood type data into national health care systems.
Analisis Resistensi Bakteri terhadap Antibiotik pada Pasien dengan Berbagai Golongan Darah Amelia Putri Az Zahra; Pramesti Listanto; Latifa Alya Khairunnisa; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 4 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i4.3212

Abstract

Acinetobacter baumannii is a major pathogenic bacterium causing nosocomial infections, known to exhibit high levels of resistance to various antibiotic classes, including β-lactams and aminoglycosides. This widespread resistance poses a significant challenge in hospital patient management, particularly in cases of severe and difficult-to-treat infections. This study aimed to analyze the resistance patterns of A. baumannii to four types of antibiotics in patients with various blood types at Dr. Soeradji Tirtonegoro General Hospital, Klaten. The research method used was a qualitative approach with a case study design. Data were obtained through in-depth interviews with healthcare workers, analysis of patient medical records, and limited observation of clinical practice. The focus of the study was directed at the relationship between patient blood type and the level of antibiotic resistance of A. baumannii. The results showed variations in resistance patterns based on blood type. Patients with blood type AB showed the highest level of resistance to all tested antibiotics, with a prevalence of multidrug resistance (MDR) reaching 85%. In contrast, patients with blood type O showed the lowest resistance and the highest proportion of non-MDR isolates compared to other groups. These findings indicate the role of host factors, namely blood type, in influencing the level of resistance of A. baumannii. The suspected mechanisms involved include differences in surface antigens that influence bacterial adhesion, biofilm formation, and the host immune response. The practical implication of this study is the need to consider blood type as a factor in empirical antibiotic therapy, especially in cases of nosocomial infections caused by A. baumannii.
Co-Authors Amelia Putri Az Zahra Devina Adira Azzahra Karina Sella Juwitasari Latifa Alya Khairunnisa Liss Dyah Dewi Arini Margaretha Alesandria Natasya Weka Pramesti Listanto Septi Puspita Kurniawati Tyara Avrilyanti Ghea Indriansyah