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All Journal Student Scientific Creativity Journal Jurnal Mahasiswa Ilmu Kesehatan
Latifa Alya Khairunnisa
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Arts Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health Social Sciences

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Peran Asam Nukleat dalam Proses Sintesis Protein: Analisis Mekanisme DNA, RNA, dan Ribosom dalam Regulasi Genetik Amelia Putri Az Azahra; Pramesti Listanto; Khotimah Nur Ramadhani; Tyara Avrilyanti Ghea Indriansyah; Latifa Alya Khairunnisa; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5501

Abstract

Nucleic acids play a vital role in the process of protein synthesis, which is the core of genetic regulation in cells. This process involves a complex mechanism of DNA, RNA, and ribosomes working in a coordinated manner. DNA (deoxyribonucleic acid) functions as a genetic blueprint that stores information for protein synthesis. Through the process of transcription, DNA is transcribed into messenger RNA (ribonucleic acid) (mRNA) in the cell nucleus. mRNA carries the genetic code to the cytoplasm, where ribosomes act as translation centers. Ribosomes, together with transfer RNA (tRNA), read the codon sequence on mRNA to determine the sequence of amino acids that will be assembled into polypeptides. This process, called translation, involves complex interactions between mRNA, tRNA, and ribosomes to ensure that the resulting protein is in accordance with genetic instructions. In addition, the role of non-coding RNA, such as microRNA and riboswitches, is also important in regulating gene expression post-transcriptionally. A deep understanding of the mechanisms of DNA, RNA, and ribosomes has opened up great opportunities in biotechnology and medicine, such as gene therapy and RNA-based drug development. Thus, the analysis of the role of nucleic acids becomes an important foundation in the exploration of molecular biology and genetics.
Pentingnya Mengetahui Golongan Darah Anda: Dampaknya pada Kesehatan dan Kehidupan Sehari-hari Tyara Avrilyanti Ghea Indriansyah; Karina Sella Juwitasari; Margaretha Alesandria Natasya Weka; Pramesti Listanto; Latifa Alya Khairunnisa; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.2947

Abstract

Knowledge of one’s blood type plays a crucial role in supporting individual health and preparedness in medical emergencies. This literature review explores the relationship between the ABO and Rhesus blood group systems and various health outcomes, including susceptibility to infections, cardiovascular risks, and biochemical implications in personalized medicine. Based on a synthesis of ten scholarly sources, the findings reveal that blood type influences vulnerability to COVID-19, gastrointestinal infections, and elevates cardiovascular disease risk particularly among non-O blood types. These results emphasize the importance of early education and blood type screening as preventive measures. The study also highlights the need for integrating blood type data into national health care systems.
Analisis Resistensi Bakteri terhadap Antibiotik pada Pasien dengan Berbagai Golongan Darah Amelia Putri Az Zahra; Pramesti Listanto; Latifa Alya Khairunnisa; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 4 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i4.3212

Abstract

Acinetobacter baumannii is a major pathogenic bacterium causing nosocomial infections, known to exhibit high levels of resistance to various antibiotic classes, including β-lactams and aminoglycosides. This widespread resistance poses a significant challenge in hospital patient management, particularly in cases of severe and difficult-to-treat infections. This study aimed to analyze the resistance patterns of A. baumannii to four types of antibiotics in patients with various blood types at Dr. Soeradji Tirtonegoro General Hospital, Klaten. The research method used was a qualitative approach with a case study design. Data were obtained through in-depth interviews with healthcare workers, analysis of patient medical records, and limited observation of clinical practice. The focus of the study was directed at the relationship between patient blood type and the level of antibiotic resistance of A. baumannii. The results showed variations in resistance patterns based on blood type. Patients with blood type AB showed the highest level of resistance to all tested antibiotics, with a prevalence of multidrug resistance (MDR) reaching 85%. In contrast, patients with blood type O showed the lowest resistance and the highest proportion of non-MDR isolates compared to other groups. These findings indicate the role of host factors, namely blood type, in influencing the level of resistance of A. baumannii. The suspected mechanisms involved include differences in surface antigens that influence bacterial adhesion, biofilm formation, and the host immune response. The practical implication of this study is the need to consider blood type as a factor in empirical antibiotic therapy, especially in cases of nosocomial infections caused by A. baumannii.
Co-Authors Amelia Putri Az Azahra Amelia Putri Az Zahra Juwita Ramadhani Octavianingrum Karina Sella Juwitasari Khotimah Nur Ramadhani Liss Dyah Dewi Arini Margaretha Alesandria Natasya Weka Pramesti Listanto Tyara Avrilyanti Ghea Indriansyah