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All Journal Medula Jurnal Ilmu Kedokteran dan Kesehatan
Naufal, Muhammad Ariq
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Identifikasi Kandungan Senyawa Aktif dan Penentuan Massa Jenis Ekstrak Etanol Daun Jambu Air (Syzygium aqueum) Naufal, Muhammad Ariq; Susianti; Daulay, Suryani Agustina; Carolia, Novita
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1320

Abstract

Water apple (Syzygium aqueum) is a plant widely utilized by publics for both consumption and medicinal purposes. Traditionally, it is used as an alternative treatment for diarrhea, headaches, and cough. The method to maximize the potential of water apple leaves is by extracting the active compounds in it. These extracts have potential as antioxidants, anti-inflammatory, anti-cholesterol, antidiabetics, and antidiarrheal agents. Previous studies have shown that water apple leaves contain various active compounds such as alkaloids, flavonoids, terpenoids, saponins, and phenolics. This research aimed to analyze the active compounds and determine the density of the water apple leaf extract. The study was conducted as a laboratory-based experimental research at the Botany Laboratory, FMIPA University of Lampung. The method employed was maceration of water apple leaves using 96% ethanol as a solvent, followed by qualitative phytochemical tests and density determination. Qualitative tests conducted included assessments for flavonoids, terpenoids, tannins, saponins, phenolics, alkaloids, and steroids. The density of the extract was determined by measuring the mass of the extract using an analytical balance and dividing it by its volume. The results showed that maceration using 96% ethanol yielded 110.62 grams of extract with a yield percentage of 11.062%. Phytochemical tests revealed the ethanol extract contained flavonoids, phenolics, tannins, saponins, alkaloids, and steroids. The density of the ethanol extract was calculated to be 0.9209 g/mL.
Literature Review: Perbandingan Efektivitas Ceftriaxone Dan Azithromycin Sebagai Tatalaksana Farmakologi Demam Tifoid Anak Naufal, Muhammad Ariq; Anjaya, Widya Fathaniah; Cindy, Syakirah; Putri, Syalika Dianisa
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 6 (2025): Volume 12 Nomor 6
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i6.18280

Abstract

Demam tifoid merupakan penyakit infeksi yang disebabkan oleh bakteri Salmonella typhi atau Salmonella paratyphi. Penyakit ini tergolong ke dalam demam enterik yang disertai gejala gastrointestinal. Tatalaksana kausatif demam tifoid melibatkan pemberian antibiotik. Beberapa antibiotik yang umum digunakan adalah ceftriaxone dan azithromycin. Penelitian ini berbentuk literature review, dengan sumber data berasal dari literatur yang diperoleh melalui Cochrane, PubMed, dan Science Direct. Hasil penelitian ini menyimpulkan bahwa ceftriaxone dan azithromycin efektif dalam mengurangi durasi demam pada pasien anak yang mengalami demam tifoid. Sebagian besar penelitian menyebutkan bahwa ceftriaxone dinilai lebih efektif dibandingkan azithromycin, namun perbedaan efektivitas antara keduanya tidak signifikan.
Co-Authors Anjaya, Widya Fathaniah Cindy, Syakirah Daulay, Suryani Agustina Novita Carolia Putri, Syalika Dianisa Susianti