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MICROBIAL CONTAMINATION IN MIXED SYRUP CONTAINING ERDOSTEIN AND CETIRIZIN STORED AT DIFFERENT STORAGE TEMPERATURE Cahyanti, Naomi Dwi; Purwaningsih, Hesti; Angelia, Inez; Deki, Yohanes Damasus Natanael; Ramadhan, Gilang
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1677

Abstract

Pharmaceutical services include drug dispensing activities, including drug compounding. Drug compounding is the process of mixing or changing ingredients to produce drugs that suit patient needs. Unmonitored storage conditions for compounded drugs in the community can affect the evaluation of the physical, chemical, and microbial contamination stability. The aim of this study was to determine the effect of storage temperature on the results of the evaluation of microbial contamination in compounding syrup pharmaceuticals, so it can provide education to the public about the storage patterns that have been carried out so far. Evaluation of microbial contamination in this study included contamination of the Total Yeast and  Mold Count (TYMC) and Total Plate Count (TPC). The objective of this study was a mixture of Erdostein syrup and cetirizine tablets. The research materials used for the microbial contamination test were mineral water, sterile water, Plate Count Agar (PCA) media, and Potato Dextrose Agar (PDA). The results of the study in the form of TYMC and TPC on day 0 were 0 cfu/mL. After 7 days of storage, microorganisms, namely TYMC, grew at room temperature (<30°C) 4.98x102 cfu/mL and cold temperature (2-8°C) 2.2x102 cfu/mL. The TPC results at room temperature storage (<30°C) were 8.33x102 cfu/mL and at cold temperatures (2-8°C) were 3.67x102 cfu/mL ...
Demonstrasi pembuatan emulgel peppermint sebagai antinyamuk dalam pencegahan demam berdarah dengue di SMK Kartini Bhakti Mandiri Cahyanti, Naomi Dwi; Firmansyah, Yura Witsqa; Angelia, Inez
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 4 (2024): December
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i4.27564

Abstract

AbstrakDemam Berdarah dengue (DBD) merupakan salah satu penyakit yang banyak berkembang di daerah tropis terutama pada awal musim penghujan dan menjadi permasalahan kesehatan yang serius karena dapat mengakibatkan kematian. Vektor pembawa dari penyakit DBD adalah nyamuk yaitu Aedes aegypti. Repelen merupakan zat yang dapat membuat serangga tidak tertarik terhadap manusia, sehingga dapat mengurangi kontak antara vektor nyamuk pembawa penyakit dengan manusia. Minyak peppermint merupakan salah satu minyak atsiri yang tidak disukai aromanya oleh nyamuk, sehingga dapat dikembangkan menjadi produk farmasi yang komersial repelen. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan siswa terkait proses pembuatan emulgel peppermint sebagai antinyamuk. Metode yang digunakan pada kegiatan tersebut adalah demonstrasi pembuatan emulgel antinyamuk minyak peppermint dan pembuatan produk emulgel yang dipraktikkan langsung oleh 28 peserta pelatihan yang berasal dari siswa/i SMK Kartini Bhakti Mandiri. Keberhasilan dari kegiatan tersebut diketahui dengan mengukur tingkat pemahaman peserta melalui pengukuran pengetahuan sebelum dan sesudah intervensi. Nilai rata-rata pengetahuan siswa sebelum dilakukan intervensi adalah 70 dan setelahnya menjadi 90. Kegiatan ini telah terbukti dalam peningkatan pengetahuan siswa dalm praktik pembuatan emulgel antinyamuk. kata kunci: emulgel; demam berdarah dengue; peppermint AbstractDengue fever is one of the most common diseases in the tropics, especially at the beginning of the rainy season, and is a serious health problem because it can cause death. The vector of DHF is the mosquito, Aedes aegypti. Repellents are substances that can make insects uninterested in humans, thus reducing contact between disease-carrying mosquito vectors and humans. peppermint oil is one of the essential oils whose aroma is disliked by mosquitoes so it can be developed into a commercial repellent pharmaceutical product. The purpose of this activity is to increase students' knowledge related to the process of making peppermint emulgel as mosquito repellent. The method used in the activity was a demonstration of making peppermint oil anti-mosquito emulgel and making emulgel products which were practiced directly by 28 trainees from students of SMK Kartini Bhakti Mandiri. The activity's success was known by measuring the level of understanding of the participants through the measurement of knowledge before and after the intervention. The average score of students' knowledge before the intervention was 70 and afterward became 90. This activity has been proven to increase student's knowledge in the practice of making anti-mosquito emulgel. Keywords: emulgel; dengue fever; peppermint
MICROBIAL CONTAMINATION IN MIXED SYRUP CONTAINING ERDOSTEIN AND CETIRIZIN STORED AT DIFFERENT STORAGE TEMPERATURE Cahyanti, Naomi Dwi; Purwaningsih, Hesti; Angelia, Inez; Deki, Yohanes Damasus Natanael; Ramadhan, Gilang
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1677

Abstract

Pharmaceutical services include drug dispensing activities, including drug compounding. Drug compounding is the process of mixing or changing ingredients to produce drugs that suit patient needs. Unmonitored storage conditions for compounded drugs in the community can affect the evaluation of the physical, chemical, and microbial contamination stability. The aim of this study was to determine the effect of storage temperature on the results of the evaluation of microbial contamination in compounding syrup pharmaceuticals, so it can provide education to the public about the storage patterns that have been carried out so far. Evaluation of microbial contamination in this study included contamination of the Total Yeast and  Mold Count (TYMC) and Total Plate Count (TPC). The objective of this study was a mixture of Erdostein syrup and cetirizine tablets. The research materials used for the microbial contamination test were mineral water, sterile water, Plate Count Agar (PCA) media, and Potato Dextrose Agar (PDA). The results of the study in the form of TYMC and TPC on day 0 were 0 cfu/mL. After 7 days of storage, microorganisms, namely TYMC, grew at room temperature (<30°C) 4.98x102 cfu/mL and cold temperature (2-8°C) 2.2x102 cfu/mL. The TPC results at room temperature storage (<30°C) were 8.33x102 cfu/mL and at cold temperatures (2-8°C) were 3.67x102 cfu/mL ...
Efektivitas edukasi melalui ceramah terhadap pengetahuan pencegahan demam berdarah dengue di SMK Kartini Bhakti Mandiri Firmansyah, Yura Witsqa; Cahyanti, Naomi Dwi; Angelia, Inez
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 2 (2024): June
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i2.23499

Abstract

AbstrakDemam berdarah dengue (DBD) dengan kodifikasi klinis A91 merupakan penyakit menular endemis yang masih terjadi di Indonesia. Penyakit tersebut masih ada karena beberapa faktor seperti kondisi lingkungan, tingkat pengetahuan, dan perilaku masyarakat. SMA Kartini Bhakti Mandiri sebagai mitra melakukan upaya pencegahan DBD dengan permohonan pelaksanaan pemberdayaan masyarakat penyuluhan DBD. Program ini bertujuan untuk meningkatkan pengetahuan, hubungan dan efektivitas pemberian edukasi melalui ceramah pada siswa. Manfaat yang dapat diperoleh adalah sebagai upaya peningkatan pemahaman siswa terhadap pencegahan dan pengendalian DBD. Pemberdayaan masyarakat dilakukan menggunakan metode ceramah dengan melibatkan 70 siswa di SMA Kartini Bhakti Mandiri. Program dilakukan pada Jumat, 23 Februari 2024 dilakukan dengan pra-pelaksanaan pre-test, pemberian materi, dan pasca-pelaksanaan (post-test). Hasil rata-rata nilai pengetahuan siswa sebelum dilakukan intervensi sebesar 65,97 dan setelah intervensi menjadi 95,14. Hasil uji hipotesis deskriptif menggunakan uji one-sample T didapatkan bahwa nilai siswa sebelum dilakukan intervensi di bawah 70 dan setelah intervensi di  atas 70. Metode ceramah dalam pemberdayaan masyarakat ini kurang efektif, karena metode ini kurang interaksi, di mana pendidik secara pasif menyampaikan informasi kepada peserta, sehingga menimbulkan kebosanan dan ketidaktertarikan. Disarankan untuk menggunakan metode pemberdayaan masyarakat lain dalam program pendidikan kesehatan. Kata kunci: ceramah; DBD; pendidikan Kesehatan; promosi kesehatan. AbstractDengue hemorrhagic fever (DHF) with clinical codification A91 is an endemic infectious disease that still occurs in Indonesia. The disease still exists due to several factors such as environmental conditions, level of knowledge, and community behavior. SMA Kartini Bhakti Mandiri as a partner made efforts to prevent DHF with a request for the implementation of community empowerment for DHF counseling. This program aims to improve knowledge, relationships, and the effectiveness of providing education through lectures to students. The benefits that can be obtained are an effort to increase students' understanding of dengue prevention and control. Community empowerment was carried out using the lecture method involving 70 students at Kartini Bhakti Mandiri High School. The program was conducted on Friday, February 23, 2024, with a pre-implementation pre-test, material delivery, and post-implementation (post-test). The average score of students' knowledge before the intervention was 65.97 and after the intervention was 95.14. The results of descriptive hypothesis testing using the one-sample T-test found that student scores before the intervention were below 70 and after the intervention were above 70. The lecture method in this community empowerment is less effective because this method lacks interaction, where educators passively convey information to participants, causing boredom and disinterest. It is recommended to use other community empowerment methods in health education programs. Keywords: dengue; health education; health promotion; lecture