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Evaluation of Virgin Coconut Oil (VCO) Soap Formulation on The Growth Inhibitory Test of Staphylococcus Aureus Cahyanti, Naomi Dwi; Tumangkeng, Decky Dekres
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol 11, No 1 (2024): February
Publisher : Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v11i1.5240

Soap is a product of the saponification reaction consisting of bases and fatty acids, which functions to clean, remove dirt and reduce bacteria on the skin. Virgin coconut oil (VCO) is pure coconut oil which contains lauric acid with antibacterial activity, another function of VCO is also useful in moisturizing the skin. Staphylococcus aureus bacteria are normal flora on the surface of the skin, which can also cause health problems if their numbers and presence are not controlled. The aim of this research was to evaluate soap formulation containing VCO which has antibacterial activity. The research was carried out experimentally with descriptive-quantitative data analysis. The results of this experiment after soap has been storage during 7 days was a solid form of soap, green in color with an apple aroma. The water content value after 7 days of storage according to SNI requirements, that is ≤ 15%. The pH value of soap during storage showed a significant difference based on the Wilcoxon Test with a sig value of 0.042 (<0.05). The antibacterial activity of VCO soap has been confirmed by comparing the inhibition zone of the sample and the positive control of commercial antibacterial soap which was formed after incubation at 370C for 24 hours. The activity of the inhibition zone of Staphylococcus aureus bacteria from samples during 7 days of storage had a significant difference based on the Wilcoxon Test with a sig value of 0.028 (<0.05). Based on research, it has been found that the soap formula contains VCO with antibacterial activity against Staphylococcus aureus.

Pengaruh pH Sabun Cair Virgin Coconut Oil (VCO) Terhadap Aktivitas Antibakteri Staphylococcus aureus Wijaya, Mariska Aurelia; Cahyanti, Naomi Dwi
Lontara Journal of Health Science and Technology Vol. 6 No. 1 (2025): Januari-Juni 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v6i1.448

Virgin coconut oil contains fatty acids that function as skin softeners and antibacterials. In general, soaps have an alkaline pH which causes the skin to feel dry. Neutral pH soap will be more acceptable to the skin , but is a suitable pH for bacterial growth. The purpose of this study was to determine the antibacterial activity of Virgin Coconut Oil soap with alkaline and neutral pH against Staphylococcus aureus. The materials used were Virgin Coconut oil, KOH, propylene glycol, glycerin, Coco DEA, hydroxypropyl methylcellulose, and citric acid. The research method used a posttest-only control group design with descriptive-quantitative data analysis. Tests were carried out by making 2 soap samples with alkaline and neutral pH, then evaluated organoleptically, pH, viscosity, specific gravity, foam height, and antibacterial activity. The results of the organoleptical evaluation of both soap samples are liquid texture, gray in color, with a vanilla aroma. The pH value of alkaline soap is 8.42 and the pH of neutral soap is 7.09. The viscosity, specific gravity, and foam height values of alkaline pH soap and neutral pH soap have met the criteria for liquid soap requirements. Both soap samples have Staphylococcus aureus antibacterial activity based on the inhibition zone formed. Statistical analysis with the Mann Whitney test showed that there was a significant difference in antibacterial activity in alkaline and neutral pH soaps, with greater inhibition in alkaline pH soap than in neutral pH.

MICROBIAL CONTAMINATION IN MIXED SYRUP CONTAINING ERDOSTEIN AND CETIRIZIN STORED AT DIFFERENT STORAGE TEMPERATURE Cahyanti, Naomi Dwi; Purwaningsih, Hesti; Angelia, Inez; Deki, Yohanes Damasus Natanael; Ramadhan, Gilang
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1677

Pharmaceutical services include drug dispensing activities, including drug compounding. Drug compounding is the process of mixing or changing ingredients to produce drugs that suit patient needs. Unmonitored storage conditions for compounded drugs in the community can affect the evaluation of the physical, chemical, and microbial contamination stability. The aim of this study was to determine the effect of storage temperature on the results of the evaluation of microbial contamination in compounding syrup pharmaceuticals, so it can provide education to the public about the storage patterns that have been carried out so far. Evaluation of microbial contamination in this study included contamination of the Total Yeast and Mold Count (TYMC) and Total Plate Count (TPC). The objective of this study was a mixture of Erdostein syrup and cetirizine tablets. The research materials used for the microbial contamination test were mineral water, sterile water, Plate Count Agar (PCA) media, and Potato Dextrose Agar (PDA). The results of the study in the form of TYMC and TPC on day 0 were 0 cfu/mL. After 7 days of storage, microorganisms, namely TYMC, grew at room temperature (<30°C) 4.98x102 cfu/mL and cold temperature (2-8°C) 2.2x102 cfu/mL. The TPC results at room temperature storage (<30°C) were 8.33x102 cfu/mL and at cold temperatures (2-8°C) were 3.67x102 cfu/mL ...

Demonstrasi pembuatan emulgel peppermint sebagai antinyamuk dalam pencegahan demam berdarah dengue di SMK Kartini Bhakti Mandiri Cahyanti, Naomi Dwi; Firmansyah, Yura Witsqa; Angelia, Inez
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 4 (2024): December
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i4.27564

AbstrakDemam Berdarah dengue (DBD) merupakan salah satu penyakit yang banyak berkembang di daerah tropis terutama pada awal musim penghujan dan menjadi permasalahan kesehatan yang serius karena dapat mengakibatkan kematian. Vektor pembawa dari penyakit DBD adalah nyamuk yaitu Aedes aegypti. Repelen merupakan zat yang dapat membuat serangga tidak tertarik terhadap manusia, sehingga dapat mengurangi kontak antara vektor nyamuk pembawa penyakit dengan manusia. Minyak peppermint merupakan salah satu minyak atsiri yang tidak disukai aromanya oleh nyamuk, sehingga dapat dikembangkan menjadi produk farmasi yang komersial repelen. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan siswa terkait proses pembuatan emulgel peppermint sebagai antinyamuk. Metode yang digunakan pada kegiatan tersebut adalah demonstrasi pembuatan emulgel antinyamuk minyak peppermint dan pembuatan produk emulgel yang dipraktikkan langsung oleh 28 peserta pelatihan yang berasal dari siswa/i SMK Kartini Bhakti Mandiri. Keberhasilan dari kegiatan tersebut diketahui dengan mengukur tingkat pemahaman peserta melalui pengukuran pengetahuan sebelum dan sesudah intervensi. Nilai rata-rata pengetahuan siswa sebelum dilakukan intervensi adalah 70 dan setelahnya menjadi 90. Kegiatan ini telah terbukti dalam peningkatan pengetahuan siswa dalm praktik pembuatan emulgel antinyamuk. kata kunci: emulgel; demam berdarah dengue; peppermint AbstractDengue fever is one of the most common diseases in the tropics, especially at the beginning of the rainy season, and is a serious health problem because it can cause death. The vector of DHF is the mosquito, Aedes aegypti. Repellents are substances that can make insects uninterested in humans, thus reducing contact between disease-carrying mosquito vectors and humans. peppermint oil is one of the essential oils whose aroma is disliked by mosquitoes so it can be developed into a commercial repellent pharmaceutical product. The purpose of this activity is to increase students' knowledge related to the process of making peppermint emulgel as mosquito repellent. The method used in the activity was a demonstration of making peppermint oil anti-mosquito emulgel and making emulgel products which were practiced directly by 28 trainees from students of SMK Kartini Bhakti Mandiri. The activity's success was known by measuring the level of understanding of the participants through the measurement of knowledge before and after the intervention. The average score of students' knowledge before the intervention was 70 and afterward became 90. This activity has been proven to increase student's knowledge in the practice of making anti-mosquito emulgel. Keywords: emulgel; dengue fever; peppermint

ANALISIS DAMPAK PENERAPAN SISTEM INFORMASI MANAJEMEN RUMAH SAKIT (SIMRS) PADA EFISIENSI WAKTU TUNGGU DI POLIKLINIK ANAK Ajie, Whisnu; Simbolon, Nadya Veronica; Cahyanti, Naomi Dwi
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2486

Waiting time is one of standards in hospitals. A waiting time of more than 30 minutes in prescription retrieval can reduce patient satisfaction. The purpose of this study was to determine the effectiveness of waiting time for prescription services after the implementation of the Hospital Management Information System (SIMRS). This research is a type of sequential explanatory design, with a combination method between quantitative methods with statistical tests and qualitative methods with interviews with pharmacy officers who use the SIMRS in the pediatric polyclinic of four people who have met the criteria “have used SIMRS for 2 years”. The results obtained, the waiting time for prescription services at the pediatric polyclinic for general prescription concoctions has met the Permenkes standard ≤30 minutes and has decreased by 10.4 minutes after implementing SIMRS. While the results for non-recipe general prescriptions have met the Permenkes standard ≤15 minutes and have decreased by 2.1 minutes after implementing SIMRS. Based on hypothesis testing, it can be concluded that there is an increase in the effectiveness of waiting time for prescription services after SIMRS is implemented for both concoction and non concoction prescriptions by looking at the significance value of the statistical test 0.00 <0.05.

MICROBIAL CONTAMINATION IN MIXED SYRUP CONTAINING ERDOSTEIN AND CETIRIZIN STORED AT DIFFERENT STORAGE TEMPERATURE Cahyanti, Naomi Dwi; Purwaningsih, Hesti; Angelia, Inez; Deki, Yohanes Damasus Natanael; Ramadhan, Gilang
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1677

Pharmaceutical services include drug dispensing activities, including drug compounding. Drug compounding is the process of mixing or changing ingredients to produce drugs that suit patient needs. Unmonitored storage conditions for compounded drugs in the community can affect the evaluation of the physical, chemical, and microbial contamination stability. The aim of this study was to determine the effect of storage temperature on the results of the evaluation of microbial contamination in compounding syrup pharmaceuticals, so it can provide education to the public about the storage patterns that have been carried out so far. Evaluation of microbial contamination in this study included contamination of the Total Yeast and Mold Count (TYMC) and Total Plate Count (TPC). The objective of this study was a mixture of Erdostein syrup and cetirizine tablets. The research materials used for the microbial contamination test were mineral water, sterile water, Plate Count Agar (PCA) media, and Potato Dextrose Agar (PDA). The results of the study in the form of TYMC and TPC on day 0 were 0 cfu/mL. After 7 days of storage, microorganisms, namely TYMC, grew at room temperature (<30°C) 4.98x102 cfu/mL and cold temperature (2-8°C) 2.2x102 cfu/mL. The TPC results at room temperature storage (<30°C) were 8.33x102 cfu/mL and at cold temperatures (2-8°C) were 3.67x102 cfu/mL ...

Evaluation of Virgin Coconut Oil (VCO) Soap Formulation on The Growth Inhibitory Test of Staphylococcus Aureus Cahyanti, Naomi Dwi; Tumangkeng, Decky Dekres
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 11 No. 1 (2024): February
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v11i1.5240

Soap is a product of the saponification reaction consisting of bases and fatty acids, which functions to clean, remove dirt and reduce bacteria on the skin. Virgin coconut oil (VCO) is pure coconut oil which contains lauric acid with antibacterial activity, another function of VCO is also useful in moisturizing the skin. Staphylococcus aureus bacteria are normal flora on the surface of the skin, which can also cause health problems if their numbers and presence are not controlled. The aim of this research was to evaluate soap formulation containing VCO which has antibacterial activity. The research was carried out experimentally with descriptive-quantitative data analysis. The results of this experiment after soap has been storage during 7 days was a solid form of soap, green in color with an apple aroma. The water content value after 7 days of storage according to SNI requirements, that is ≤ 15%. The pH value of soap during storage showed a significant difference based on the Wilcoxon Test with a sig value of 0.042 (<0.05). The antibacterial activity of VCO soap has been confirmed by comparing the inhibition zone of the sample and the positive control of commercial antibacterial soap which was formed after incubation at 370C for 24 hours. The activity of the inhibition zone of Staphylococcus aureus bacteria from samples during 7 days of storage had a significant difference based on the Wilcoxon Test with a sig value of 0.028 (<0.05). Based on research, it has been found that the soap formula contains VCO with antibacterial activity against Staphylococcus aureus.

Efektivitas edukasi melalui ceramah terhadap pengetahuan pencegahan demam berdarah dengue di SMK Kartini Bhakti Mandiri Firmansyah, Yura Witsqa; Cahyanti, Naomi Dwi; Angelia, Inez
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 2 (2024): June
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i2.23499

AbstrakDemam berdarah dengue (DBD) dengan kodifikasi klinis A91 merupakan penyakit menular endemis yang masih terjadi di Indonesia. Penyakit tersebut masih ada karena beberapa faktor seperti kondisi lingkungan, tingkat pengetahuan, dan perilaku masyarakat. SMA Kartini Bhakti Mandiri sebagai mitra melakukan upaya pencegahan DBD dengan permohonan pelaksanaan pemberdayaan masyarakat penyuluhan DBD. Program ini bertujuan untuk meningkatkan pengetahuan, hubungan dan efektivitas pemberian edukasi melalui ceramah pada siswa. Manfaat yang dapat diperoleh adalah sebagai upaya peningkatan pemahaman siswa terhadap pencegahan dan pengendalian DBD. Pemberdayaan masyarakat dilakukan menggunakan metode ceramah dengan melibatkan 70 siswa di SMA Kartini Bhakti Mandiri. Program dilakukan pada Jumat, 23 Februari 2024 dilakukan dengan pra-pelaksanaan pre-test, pemberian materi, dan pasca-pelaksanaan (post-test). Hasil rata-rata nilai pengetahuan siswa sebelum dilakukan intervensi sebesar 65,97 dan setelah intervensi menjadi 95,14. Hasil uji hipotesis deskriptif menggunakan uji one-sample T didapatkan bahwa nilai siswa sebelum dilakukan intervensi di bawah 70 dan setelah intervensi di atas 70. Metode ceramah dalam pemberdayaan masyarakat ini kurang efektif, karena metode ini kurang interaksi, di mana pendidik secara pasif menyampaikan informasi kepada peserta, sehingga menimbulkan kebosanan dan ketidaktertarikan. Disarankan untuk menggunakan metode pemberdayaan masyarakat lain dalam program pendidikan kesehatan. Kata kunci: ceramah; DBD; pendidikan Kesehatan; promosi kesehatan. AbstractDengue hemorrhagic fever (DHF) with clinical codification A91 is an endemic infectious disease that still occurs in Indonesia. The disease still exists due to several factors such as environmental conditions, level of knowledge, and community behavior. SMA Kartini Bhakti Mandiri as a partner made efforts to prevent DHF with a request for the implementation of community empowerment for DHF counseling. This program aims to improve knowledge, relationships, and the effectiveness of providing education through lectures to students. The benefits that can be obtained are an effort to increase students' understanding of dengue prevention and control. Community empowerment was carried out using the lecture method involving 70 students at Kartini Bhakti Mandiri High School. The program was conducted on Friday, February 23, 2024, with a pre-implementation pre-test, material delivery, and post-implementation (post-test). The average score of students' knowledge before the intervention was 65.97 and after the intervention was 95.14. The results of descriptive hypothesis testing using the one-sample T-test found that student scores before the intervention were below 70 and after the intervention were above 70. The lecture method in this community empowerment is less effective because this method lacks interaction, where educators passively convey information to participants, causing boredom and disinterest. It is recommended to use other community empowerment methods in health education programs. Keywords: dengue; health education; health promotion; lecture

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