Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Scientific Journal
Hafizhah, Ataya
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Bone Metastasis Disease from Mucinous Carcinoma of the Breast: A Rare Case Report with Immunohistochemical Confirmation Novianti, Hera; Mayorita, Pamelia; Oktora, Meta Zulyati; Hafizhah, Ataya; Muhammad, Almu
Scientific Journal Vol. 4 No. 1 (2025): SCIENA Volume IV No 1, January 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v4i1.194

Abstract

Background: Mucinous carcinoma of the breast (MCB) is a rare histological subtype of invasive breast cancer, comprising 1-7% of all breast carcinomas. It is generally associated with a favorable prognosis due to its indolent course and low metastatic potential. However, distant metastases, including to the bone, are exceptionally rare and pose diagnostic and therapeutic challenges. Case Presentation: We present a case of a 64-year-old woman with a history of MCB who developed progressive back pain and lower limb weakness. MRI showed multiple osteolytic lesions with spinal cord compression. A CT-guided biopsy confirmed metastatic mucinous carcinoma, and immunohistochemical (IHC) staining demonstrated GATA3 positivity, confirming breast origin. The patient received denosumab, aromatase inhibitors, and palliative radiotherapy. Conclusion: This case highlights the importance of considering bone metastases in patients with a history of MCB presenting with skeletal-related events. IHC, particularly GATA3, is crucial in confirming the metastatic origin and guiding targeted treatment strategies.
Co-Authors Mayorita, Pamelia Muhammad, Almu Novianti, Hera Oktora, Meta Zulyati