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All Journal Competitor : Jurnal Pendidikan Kepelatihan Olahraga Rumphius Pattimura Biological Journal Indonesian Journal of Pharmacology and Therapy Indonesian Journal of Sport Physical Therapy (IJSPT)
Anggraeni, Andi Sri Dewi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Medicine & Pharmacology

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The Influence Of The Forehand Grip On Short Service Ability In Badminton Ruslan, Ruslan; Rusli, Rusli; Sarifin, Sarifin; Surur, Andi Ainun Zulkiah; Anggraeni, Andi Sri Dewi
COMPETITOR: Jurnal Pendidikan Kepelatihan Olahraga Vol 17, No 1 (2025): February
Publisher : UNIVERSITAS NEGERI MAKASSAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/cjpko.v17i1.71189

Abstract

This study aims to determine the effect of the handle on the short-service ability of badminton games in Penjaskesrek students. This research is a pre-experiment, namely two Group pretest-posttest design, the population in the study were 40 students of Physical Education Class 2022, Makassar State University. The data collection technique uses a short service test instrument, namely the forehand grip service test grip. Based on the data analysis, the results obtained from the pretest average value of the forehand grip ability of 32.3500, the average posttest value of the forehand grip of 52.6000, the value of t count> is 7.818, the significance value of the probability is 0.000, and the t table is 2.818. and the mean value of the backhand grip pre-test ability of 32.1500, the average value of, the significance value of the probability of 0.000, and the t table of 2.746. the value of t table 0.050 is greater than t count 0.025 and the value of sig <a (0.000 <0.05), so it can be seen that Ho is accepted and H1 is accepted. This means that there is a significant effect of the effect of the forehand grip of badminton on students by 95%.
Evaluation of Analgesic Activity Corypalmine and Panasenoside Compounds on Cox-2 Receptors In-Silico Lesbatta, Kezia Josawel; Watuguly, Theopilus Wilhelmus; Kakisina, Alter Glen; Anggraeni, Andi Sri Dewi
RUMPHIUS Vol 7 No 1 (2025): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv7i1p031-037

Abstract

Pain is a mechanism that occurs due to stimulation of nociceptors as pain receptors that cause ongoing or future tissue damage. Analgesic drugs that are usually used are COX-2 inhibitor drugs that can inhibit the activity of the COX-2 enzyme in synthesizing Prostaglandins (PG) which respond to pain and inflammation. Specific research on active compounds such as corypalmine and panasenoside related to their effects as analgesics has not been widely carried out, so it is necessary to predict the effects of both compounds by analyzing their activity on the COX-2 protein through in silico docking studies. This study aims to see the analgesic activity between the two compounds as COX-2 inhibitors. Testing was carried out through the stages of protein and ligand preparation, method validation, molecular docking of corypalmine and panasenoside compounds with COX-2 and visualization of bonds using Ligplot+. The results showed that the corypalmine docking score was more negative than panasenoside on COX-2, respectively -60.33 and -42.02. It can be concluded that the corypalmine compound is able to bind more strongly to COOX-2 and predicted to have a strong and more stable analgesic effect than panacea.
Liposome as carrier therapy for Alzheimer’s disease Anggraeni, Andi Sri Dewi; Arsita, Emilia Vivi; Suwarman, Adika; Mustofa
Indonesian Journal of Pharmacology and Therapy Vol 3 No 2 (2022)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.2315

Abstract

Alzheimer's disease (AD) is the most common type of dementia. Approximately 50 million people suffer from Alzheimer's and it is expected to increase more than 100 million by 2050. According to the Diagnostic and Statistical Manual of Mental Disorders V (DSM-V), the diagnosis of AD has an onset of memory impairment and cognitive decline. Effective treatment of AD is a major challenge in the field of pharmacy and science due to the restriction from blood brain barrier (BBB). This causes poor access to pills or oral administration. Liposome as a part of nanoparticle showed to be a potential AD treatment because of its biocompatibility, flexibility, and capability to carry various therapeutic molecules across the BBB and into brain cells. Several types of liposomes provide varied therapy effect. Some factors which determine liposomes effectiveness are its structure, mechanism of action; formed; and delivery, and its preparation method. This article reviewed liposomes characteristics which has potency as carrier therapy for AD.
Peningkatan Keterampilan Penanganan Pertama Cedera Sprain Ankle melalui Pelatihan Metode RICE (Rest, Ice, Compression, Elevation) pada Atlet Sepakbola Surur, Andi Ainun Zulkiah; Arimbi; Mukrim, Harvina; Anggraeni, Andi Sri Dewi; Febriyanda, Andini
Indonesian Journal of Sport Physical Therapy (IJSPT) Vol. 1 No. 1 (2025): Februari
Publisher : Jurusan Fisioterapi Fakultas Ilmu Keolahragaan Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakang: Sprain ankle merupakan jenis cedera yang sering dialami oleh atlet sepakbola. Namun, penanganan yang cepat dan tepat merupakan hal krusial dalam proses pemulihan. Penelitian ini bertujuan untuk mengevaluasi efektivitas edukasi metode RICE (Rest, Ice, Compression, Elevation) terhadap peningkatan keterampilan penanganan pertama pada atlet sepakbola PSM U-18. Metode: Quasi eksperimental dengan desain pre dan post test. Subjek penelitian terdiri dari 35 atlet U-18 yang dipilih menggunakan metode total sampling. Intervensi berupa pelatihan metode RICE dilakukan selama dua sesi. Data keterampilan atlet dikumpulkan menggunakan anket berbasis checklist sebelum dan sesudah pelatihan. Analisis data menggunakan uji statistik paired t-test untuk mengetahui perbedaan signifikan antara hasil pre dan post test. Hasil: terdapat peningkatan yang signifikan (p<0,05) terhadap keterampilan atlet dalam melakukan penanganan pertama cedera sprain ankle setelah diberikan edukasi metode RICE. Kesimpulan: metode RICE dapat menjadi pendekatan edukasi yang bermanfaat dalam penanganan sprain ankle akut, khususnya dalam mengasah keterampilan penanganan cedera di lapangan. Diharapkan para atlet PSM U-18 dapat menerapkan dengan baik edukasi tersebut.
Co-Authors Arimbi Emilia Vivi Arsita Febriyanda, Andini Kakisina, Alter Glen Lesbatta, Kezia Josawel Mukrim, Harvina Mustofa Mustofa R. Rusli Ruslan Ruslan Sarifin, Sarifin Surur, Andi Ainun Zulkiah Suwarman, Adika Theopilus W Watuguly