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Literature Review : The Effect Of Work Stress On The Risk Of Hypertension Ika Alfina Sari.B; Imran Safei; Dzul Ikram
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Abstract

Hypertension is a leading cause of morbidity and mortality worldwide, with work-related stress identified as a significant risk factor. This study aims to explore the relationship between work stress and the risk of hypertension through a literature review (narrative review). Literature data were obtained from databases such as PubMed and Google Scholar, with inclusion criteria encompassing studies published in the last five years. The analysis results indicate that work stress can elevate blood pressure through the mechanism of stress hormone release, such as cortisol and adrenaline. Additionally, work-related factors such as high workload, long working hours, and unfavorable working environmental conditions contribute to an increased risk of hypertension. The research also indicates that workers experiencing work stress have a higher prevalence of hypertension compared to those who do not experience stress. Preventing hypertension in the workplace requires a holistic approach, including effective stress management, reduction of excessive working hours, and promotion of healthy lifestyles among workers. Company policy interventions and regulations related to occupational health are crucial for reducing the incidence of hypertension among workers. By understanding the relationship between work stress and hypertension, it is hoped that more effective preventive measures can be taken to enhance the health and well-being of workers.
Effect of Bandotan (Ageratum conyzoides Linn) leaf extract and wild honey provision on cut wound healing in mice Vivi Chairun Nisa; Syamsu Rijal; Marzelina Karim; Rachmat Faisal Syamsu; Dzul Ikram
International Journal of Health Science and Technology Vol. 6 No. 3 (2025): April
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v6i3.3963

Abstract

Cuts are a common form of injury caused by trauma from sharp objects such as knives, razor blades, or other sharp objects. In Indonesia, traditional wound treatment is still widely used, one of which is by using Bandotan leaves (Ageratum conyzoides Linn), which is known to have the ability to stop bleeding and accelerate wound healing. In addition, wild honey from Apis dorsata bees also contains various active compounds that can be significant for the wound healing process. Data from Riskesdas (Riset Kesehatan Dasar - Basic Health Research) showed that the prevalence of cut/slash/stab wound cases in South Sulawesi in 2018 reached 27.76%, so an effective and natural alternative treatment is needed. This study aims to determine the content of phytochemical compounds in Bandotan leaf extract and wild honey; and compare their effectiveness on cut healing in mice (Mus musculus), both macroscopically and histologically. This study employed a quantitative experimental method with a Pretest-Posttest Control Group Design. The results show that Bandotan leaf extract contains alkaloids, flavonoids, steroids, and saponins; while wild honey contains flavonoids and saponins. Macroscopically, wild honey is more effective in accelerating wound healing than the other groups. However, microscopically, the Bandotan leaf group shows higher epidermal thickness. Complete re-epithelialization occurs in all groups, while keratinization does not only occur in the negative control group. In conclusion, wild honey is more clinically effective in accelerating wound healing, while Bandotan leaves show potential for tissue regeneration based on histology.