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Aida Fitri Harahap
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Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Engineering Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health

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Hubungan Glasgow Coma Scale (GCS) dan Kadar Trombosit dengan Lama Rawat Pasien Sepsis di RSU Cut Meutia Aceh Utara Aida Fitri Harahap; Muhammad Sayuti; Meutia Maulina
Sci-tech Journal Vol. 4 No. 1 (2025): Sci-Tech Journal (STJ) In Press
Publisher : MES Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56709/stj.v4i1.704

Abstract

Sepsis is a life-threatening organ malfunction caused by the dysregulation of the body's reaction to infection. Septic dysfunction can occur in almost any organ, which ends in multi-organ disfunction. Decreased thrombocyte levels and decreased awareness as parameters of organ dysfunction in sepsis can increase the risk of prolonged treatment. The aim of the research is to find out the relationship between GCS and thrombocyte levels with the long-term treatment of sepsis patients. Research with cross-sectional analytical observational methods, carried out at Cut Meutia North Aceh RSU, September - November 2023. The sample was 63 patients diagnosed with sepsis according to the inclusion and exclusion criteria obtained from medical records. The results of the study included 43 men (68.3%), 35 men (55.6%) with long-term treatment (>6 days), 32 people (50.8%) with normal thrombocyte levels (150,000-450,000/μl), and 51 people (81%) with GCS 15 or composmentis. Spearman's results showed no significant relationship between thrombocyte levels (p=0.846) and GCS (p =0.153) with the length of treatment of sepsis patients.
Sindrom Koronari Kronis Aida Fitri Harahap
Inovasi Kesehatan Global Vol. 3 No. 2 (2026): Mei : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v3i2.2991

Abstract

Chronic Coronary Syndrome (CCS) is a contemporary term that replaces stable coronary artery disease (CAD) and describes a spectrum of clinical conditions resulting from chronic abnormalities of the coronary arteries. This condition is characterized by a mismatch between myocardial oxygen supply and demand that is transient and reversible, commonly presenting as stable angina pectoris. CCS contributes significantly to global cardiovascular morbidity and mortality, including in Indonesia. The underlying pathophysiology primarily involves atherosclerosis and microvascular dysfunction leading to myocardial ischemia. Diagnosis is established through comprehensive history taking, physical examination, and both invasive and non-invasive investigations such as electrocardiography, stress testing, and cardiac imaging. Risk stratification using pre-test probability plays a crucial role in guiding further diagnostic evaluation. The management of CCS aims to relieve symptoms and prevent adverse cardiovascular events through pharmacological and non-pharmacological approaches, as well as revascularization when indicated. Pharmacological therapy includes antianginal agents, antiplatelet drugs, and lipid-lowering agents, while lifestyle modifications such as smoking cessation, healthy diet, and regular physical activity are essential in preventing disease progression. With accurate diagnosis and comprehensive management, the morbidity and mortality associated with CCS can be reduced.
Co-Authors Meutia Maulina Muhammad Sayuti