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DOSAGES ANALYSIS OF HYPERBARIC OXYGEN THERAPY TO IMPROVING COGNITIVE FUNCTION IN PATIENTS POST-TRAUMATIC BRAIN INJURY: A REVIEW Nuri, Almas; Edi, Djatiwidodo; Anindya, Pramita; Ilmawan, Moh. Fathi
MNJ (Malang Neurology Journal) Vol. 11 No. 1 (2025): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.01.24

Abstract

Background: Traumatic brain injury is a type of intracranial injury caused by a mechanical impact that causes anatomical and physiological damage to the brain. Globally, there are 50 million cases of traumatic brain injury each year that cause 10 million deaths and/or hospitalizations. Hyperbaric oxygen therapy is a therapy that uses 100% oxygen at pressures greater than 1 Atmosphere Absolute  (ATA) to increase tissue oxygenation and repair damaged tissue. This study was made to determine the effect of hyperbaric oxygen therapy on improving cognitive function in post-traumatic brain injury patients and the mechanisms underlying it. Objective: To determine the dose of hyperbaric oxygen therapy that can trigger improved cognitive function in post-traumatic brain injury patients, as well as the side effects. Methods: This research is descriptive research and uses the literature study method. In collecting data, using all journals with the search keywords "hyperbaric oxygen therapy" "traumatic brain injury" "hyperbaric oxygen therapy for TBI" "HBOT and TBI" "oxygen therapy and brain injury" published in 2017 - 2022 and indexed by Scimago Journal & Country Rank (SJR) and/or Science And Technology Index (SINTA) then new conclusions and descriptions are made. Results: After selecting 262 journals, ten journals met the inclusion and exclusion criteria. The ten journals stated that there was an effect of hyperbaric oxygen therapy on improving cognitive function in post-traumatic brain injury patients. assessment of improvement in cognitive function in the attached journal, assessed with different parameters. Conclusion: Hyperbaric oxygen therapy is a potential therapy to accelerate cognitive function improvement in post-traumatic brain injury patients.
The Relationship Between Hba1c Levels in Type 2 Diabetes Mellitus Patients and Clinical Manifestations of Diabetic Microangiopathy Neuropathy With The Incidence of Erectile Dysfunction Pursetyo, Travesthi Dian; Ilmawan, Moh. Fathi; Yudadi, Redemptus; Risma, Risma
Eduvest - Journal of Universal Studies Vol. 5 No. 5 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i5.50098

Abstract

Type 2 diabetes mellitus is a chronic disease that can lead to various complications. This study aims to analyze the relationship between HbA1c levels and the clinical manifestations of diabetic microangiopathy neuropathy with the incidence of erectile dysfunction in patients with type 2 diabetes mellitus. The objective is to understand the prevalence of the relationship between HbA1c levels, the clinical manifestations of diabetic microangiopathy neuropathy, and the occurrence of erectile dysfunction in patients with type 2 diabetes mellitus. This study used an observational analytical design with a cross-sectional approach. The sample consisted of 61 male patients who underwent examination at RSPAL dr. Ramelan Surabaya from July to September 2024. Data was collected through interviews using the International Index of Erectile Function (IIEF-5) questionnaire, along with secondary data on HbA1c levels and symptoms of diabetic neuropathy. Statistical analysis was performed using the Chi-Square test to identify relationships between the study variables. The results of the study showed a significant relationship between HbA1c levels and the incidence of erectile dysfunction. However, there was no significant relationship between the clinical manifestations of diabetic microangiopathy neuropathy and erectile dysfunction, as indicated by the Chi-Square test. The conclusions of this study are: first, there is a strong relationship between uncontrolled HbA1c levels and the incidence of erectile dysfunction, and second, although the clinical manifestations of diabetic microangiopathy neuropathy are common in patients with type 2 diabetes mellitus, no direct significant relationship was found between the clinical manifestations of diabetic microangiopathy neuropathy and erectile dysfunction.