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All Journal Medica Hospitalia Indonesian Journal of Cancer Eduvest - Journal of Universal Studies Surabaya Biomedical Journal
Yudadi, Redemptus
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Concomitant Colon Adenocarcinoma And Tuberculous Lymphadenitis Arya Abisatya, Albertus Magnus; Prameswari, Ajeng Andini; Fauzi, Agung Rahmat; Febrianto, Aji Pratama; Nugroho, Alexander Steven; Andisari, Hendrata Erry; Harijono, Pandu; Yudadi, Redemptus
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 3 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i3.1007

Abstract

BACKGROUND : Colon involvement in tuberculosis infection is a rare event. The coexistence of colon carcinoma and tuberculous lesions of the colon is less frequently reported. Carcinoma and tuberculosis of the colon can occur at the same site or at different sites. The occurrence of two pathologies at the same site is much less common. CASE PRESENTATION : A 52 year old woman complained of difficulty defecating, an enlarged stomach, pain and decreased appetite and weight loss within one month. On clinical examination, the abdomen appeared convex, slightly distended, and tenderness in the left lower iliac quadrant. Radiological examination supported the diagnose of partial obstructive ileus. The patient was diagnosed with adenocarcinoma of the ascending colon until the hepatic flexura was confirmed through surgery and histopathological examination. On histopathological examination, adenocarcinoma of the colon was found to coexistence with tuberculous lymphadenitis of the colon. CONCLUSION : The etiological and pathophysiological relationship between tuberculous lymphadenitis and colon cancer is still under debate, but surgeons need to be aware of this occurrence, to choose treatment and avoid post-operative worsening.
Systemic Immune-Inflammation Index (SII) and NeutrophilLymphocyte Ratio (NLR) as a Promising Predictor for Advanced Stage Events during the Follow-Up Period in Hepato-Gastrointestinal Cancer Patients Zenjaya, Kellyn Trycia; Biutifasari, Verna; Yudadi, Redemptus; Wibowo, Prajogo
Indonesian Journal of Cancer Vol 18, No 4 (2024): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i4.1186

Abstract

Background: Tumor microenvironment has shown the role of inflammation in its progressivity. The heterogeneity of prognosis at the same TNM stage makes it difficult to classify patients who are more at risk of developing advanced stages. This study aimed to provide a deeper insight into the potential of cheap inflammation markers based on the Systemic ImmuneInflammation Index (SII) and Neutrophil-Lymphocyte Ratio (NLR) to predict the advanced stage during the follow-up period in patients with hepato-gastrointestinal cancer.Methods: Case-control research was conducted using 120 data of patients with hepatogastrointestinal cancer (Colorectal cancer (CRC), hepatocellular carcinoma (HCC), gastrointestinal stromal tumor (GIST), esophageal adenocarcinoma (EAC), pancreatic ductal adenocarcinoma (PDAC), cholangio carcinoma (CCA)) taken from patient medical records. The patients were divided into case and control groups based on the presence of advanced stage events during the follow-up period that were further classified by the NLR and SII value. The advanced-stage events were analyzed and compared between the two groups using Chi-Square and logistic regression analysis to perceive the predictive value of each ratio. Results: Patients with advanced-stage hepato-gastrointestinal cancer had higher NLR and SII than patients without advanced stage (p 0.001). The group of patients with advanced stages had an average NLR of 18.45 and an SII of 6588.13. The group of patients without advanced stages had an average NLR of 5.12 and SII of 1545.01. The cut-off value was determined using the ROC curve, for NLR was 6.48 (92.5% sensitivity and 71.2% specificity), and for SII was 2264.24 (92.5% sensitivity and 76.2% specificity).Conclusions: NLR and SII are cheap markers and have considerable potential for predicting advanced stage during the follow-up period in patients with hepato-gastrointestinal cancer. SII is more accurate as a predictor than NLR. These tools can be very useful in identifying the high-risk patients among the same TNM stage.
The Relationship Between Hba1c Levels in Type 2 Diabetes Mellitus Patients and Clinical Manifestations of Diabetic Microangiopathy Neuropathy With The Incidence of Erectile Dysfunction Pursetyo, Travesthi Dian; Ilmawan, Moh. Fathi; Yudadi, Redemptus; Risma, Risma
Eduvest - Journal of Universal Studies Vol. 5 No. 5 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i5.50098

Abstract

Type 2 diabetes mellitus is a chronic disease that can lead to various complications. This study aims to analyze the relationship between HbA1c levels and the clinical manifestations of diabetic microangiopathy neuropathy with the incidence of erectile dysfunction in patients with type 2 diabetes mellitus. The objective is to understand the prevalence of the relationship between HbA1c levels, the clinical manifestations of diabetic microangiopathy neuropathy, and the occurrence of erectile dysfunction in patients with type 2 diabetes mellitus. This study used an observational analytical design with a cross-sectional approach. The sample consisted of 61 male patients who underwent examination at RSPAL dr. Ramelan Surabaya from July to September 2024. Data was collected through interviews using the International Index of Erectile Function (IIEF-5) questionnaire, along with secondary data on HbA1c levels and symptoms of diabetic neuropathy. Statistical analysis was performed using the Chi-Square test to identify relationships between the study variables. The results of the study showed a significant relationship between HbA1c levels and the incidence of erectile dysfunction. However, there was no significant relationship between the clinical manifestations of diabetic microangiopathy neuropathy and erectile dysfunction, as indicated by the Chi-Square test. The conclusions of this study are: first, there is a strong relationship between uncontrolled HbA1c levels and the incidence of erectile dysfunction, and second, although the clinical manifestations of diabetic microangiopathy neuropathy are common in patients with type 2 diabetes mellitus, no direct significant relationship was found between the clinical manifestations of diabetic microangiopathy neuropathy and erectile dysfunction.
CHOLEDOCHAL CYST: SERIAL KASUS: 51-57 Yudadi, Redemptus; Diarsvitri, Wienta
Surabaya Biomedical Journal Vol. 1 No. 1 (2021): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v1i1.8

Abstract

Penelitian ini bertujuan untuk melaporkan diagnosis dan manajemen dari beberapa kasus langka choledochal cyst (CC), kelainan kongenital saluran bilier yang ditangani di Sub Departemen Bedah Digestif RSPAL Dr. Ramelan, Surabaya. Artikel ini disusun berdasarkan laporan tiga serial kasus CC yang ditangani di Sub Departmen Bedah Digestif RSPAL dr. Ramelan tahun 2018-2020. Dilaporkan tiga kasus CC pada pasien perempuan: dua kasus pada pasien berusia 20 tahun, dan satu kasus pada pasien berusia 64 tahun. Pada ketiga pasien tersebut ditemukan gejala berupa nyeri abdomen di daerah epigastrium, dua orang dengan ikterus intermiten dan seorang pasien dengan kondisi situs inversus. Hanya seorang pasien teraba massa di daerah epigastrium. Pada pemeriksaan penunjang dengan USG abdomen, MRCP dan cholangiografi intraoperatif ditemukan gambaran dilatasi kistik choledocus (common bile duct) yang mendukung suatu CC, dan tidak tampak batu di saluran bilier. Pada saat operasi, pada ketiga pasien tersebut ditemukan CC tipe I (klasifikasi Todani tipe I) dengan bentuk fusiformis. Diputuskan dilakukan eksisi CC dan rekonstruksi biliodigestif dengan hepatikojejunostomi Roux-en-Y. Hasil pemeriksaan patologi anatomi menunjukkan tanda radang dinding saluran bilier dan tidak ditemukan tanda keganasan. Pasca operasi, kondisi ketiga pasien tersebut baik. CC pada pasien dewasa sering ditemukan dengan gejala yang tidak jelas dan disertai komplikasi. Manajemen CC dengan eksisi dan rekonstruksi biliodigestif hepatikojejunostomi Roux-en-Y berhasil dengan baik.
Co-Authors Andisari, Hendrata Erry Arya Abisatya, Albertus Magnus Biutifasari, Verna Fauzi, Agung Rahmat Febrianto, Aji Pratama Harijono, Pandu Ilmawan, Moh. Fathi Nugroho, Alexander Steven Prameswari, Ajeng Andini Pursetyo, Travesthi Dian Risma Risma, Risma Wibowo, Prajogo Wienta Diarsvitri Zenjaya, Kellyn Trycia