Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology JSFK (Jurnal Sains Farmasi & Klinis)
Seran, Yuvina
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Nanoparticle Technology for Development of Immunostimulant Drugs Using Natural Product : Narrative Review Seran, Yuvina
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.53217

Abstract

The field of nanotechnology focuses on systems at the nanometer scale. Nanotechnology is used in the medical field for drug development, medical imaging, and gene therapy. One application of nanotechnology is nanoparticles. Nanoparticles have sizes in the nanometer range, with a scale of 1 to 100 nm. Nanoparticles can be designed to stimulate the immune system and improve the immune response. Literature study using research articles from national and international journals the application Publish or Perish 8 based on the keywords "Immunostimulants, Nanotechnology, nanoparticle, gold nanoparticle, and silver nanoparticle." Based on searching various literature studies, it is proven that nanoparticle preparations can increase immunostimulants with various testing instruments that are often found, namely FTIR (Fourier Transform Infrared), WHICH (Scanning Electron Microscopy), XRD (X-ray Diffraction), HE HAS (Transmission Electron Microscopy), particle size, zeta potential, and spectroscopy UV-visible. Nanoparticles can be an effective drug delivery system and can help maintain the immune system in the body.
Formulation and Characterization of Solid Self Nano Emulsifying Drug Delivery System (S-SNEDDS) Loading Curcuma xanthorrhiza Extract Syukri, Yandi; Seran, Yuvina; Hannie Fitriani; Ramadhani, Arba Pramundita; Taher, Muhammad
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 3 (2024): J Sains Farm Klin 11(3), December 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.3.169-178.2024

Abstract

Curcuma xanthorrhiza has an active component xanthorrhizol that is poorly soluble in water, resulting in limited absorption and bioavailability. Liquid Self Nano Emulsifying Drug Delivery System (SNEDDS) dosage formulations can improve its solubility and absorption due to its small particle size. Solid SNEDDS technology significantly overcomes some of problems in liquid SNEDDS preparations to improve the stability of liquid formulations. This study aims to formulate and characterize Curcuma xanthorrhiza S-SNEDDS preparation. SNEDDS was characterized by particle size and thermodynamic tests. Method of making S-SNEDDS uses two ways, absorption of porous compounds and spray drying. S-SNEDDS were characterized by testing infrared spectra, X-ray diffraction, scanning electron microscopy, microbial contamination and particle flow properties. Optimal S-SNEDDS formulation with 2 formulas namely F7 and F11 mannitol carrier. FTIR testing showed no interacting compounds. SEM and X-ray diffraction testing of F7 showed that the preparation was semicrystalline. While F11 described the preparation as much more crystalline due to the high content of mannitol. The microbial contamination test detected no microorganism compounds. In addition, the particle flow properties obtained a result of 02.53 seconds with a height of 24.95 mm. It is concluded that the S-SNEDDS formula F7 of Curcuma xanthorrhiza has semicrystalline preparation criteria.
Co-Authors Hannie Fitriani Ramadhani, Arba Pramundita Taher, Muhammad Yandi Syukri