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All Journal Smart Medical Journal Indonesian Journal of Medicine
Adnyana, Ida Bagus Budhi Surya
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Health Professions Medicine & Pharmacology Public Health

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The Relationship between Tumor Size and Carcinoembryonic Antigen (CEA) Levels in Stage IV Colorectal Adenocarcinoma Patients at Dr. Moewardi Hospital, Indonesia Eri, Rakhmawati Susetyaning; Kusumaningrum, Sulistyani; Widiastuti, Widiastuti; Wujoso, Hari; Adnyana, Ida Bagus Budhi Surya; Putro, Prasetyo Sarwono
Indonesian Journal of Medicine Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.994 KB) | DOI: 10.26911/theijmed.2021.6.3.419

Abstract

Background: Colorectal adenocarcinoma is one of the most common types of colorectal cancer based on histopathology, accounting for about 10% of cancer cases diagnosed worldwide each year. Tumor size and levels of carcinoembryonic antigen (CEA) are used to determine the presence and evaluation of colorectal cancer. However, studies on the correlation between the size of colorectal cancer based on CT scan abdominal with contrast and the CEA levels are still very minimal in the Indonesian population. This study aimed to analyze the relationship between tumor size examined by abdominal CT scan with contrast and carcinoembryonic antigen (CEA) levels in stage IV colorectal adenocarcinoma patients.Subjects and Method: A cross-sectional study was conducted at the radiology department, Dr. Moewardi hospital, Surakarta, from February 2021 to July 2021. A total of 40 patients with stage IV colorectal adenocarcinoma were selected in this study. The patient already had the examination results of blood CEA levels and performed an abdominal CT scan with contrast. The dependent variable was blood CEA levels. The independent variable was tumor size. Data were collected from medical records and analyzed by the Spearman test.Results: There was a positive and significant relationship between tumor size and CEA levels (r= 0.47; p= 0.003).Conclusion: Tumor size is positively correlated to blood CEA levels in patients with stage IV colorectal adenocarcinoma.Keywords: colorectal adenocarcinoma, contrast abdominal CT scan, carcinoembryonic antigen (CEA).Correspondence: Sulistyani Kusumaningrum. Department of Radiology Dr. Moewardi Hospital/ Faculty of Medicine of Universitas Sebelas Maret, Surakarta. Email: sulistyani_sprad@staff.uns.ac.idIndonesian Journal of Medicine (2021), 06(03): 285-290https://doi.­org/10.26911/theijmed.2021.06.03.05
Gallstone Ileus Managed with One-Stage Laparotomy : A Rare Case Report Nindya Wiharjanto, Dorothy Eugene; Adnyana, Ida Bagus Budhi Surya; Heryadi, Afrizal Tri
Smart Medical Journal Vol 8, No 2 (2025): August
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i2.103110

Abstract

Introduction: Gallstone ileus is defined as a mechanical intestinal obstruction due to impaction of one are more gallstones within the gastrointestinal tract. Gallstone ileus has shown a constant incidence of 30-35 cases/1000000 admissions over a 45-year period. Most of the symptoms and signs of gallstone ileus are nonspecific. Case Presentation: A 61-year-old man presented with abdominal pain and vomiting 3 days prior to hospital admission. The abdominal pain was felt on all of the regions of the abdomen and did not subside with rest. The patient has a history of having gallstones on November 2021. On 3 views abdominal x-ray, it showed high-grade ileus. Exploratory laparotomy with ileal enterotomy were performed incidentally to evacuate the gallstones and continued with cholecystectomy. The patient’s condition had improved after receiving surgery. We also provided post-operative pain management and maintained the fluid, electrolyte, and metabolic balances for the patient. Discussion: Gallstone ileus is a rare complication of cholelithiasis. Its intermittency of symptoms could also interfere the diagnosis. Therefore, it is associated with relatively high rates of morbidity and mortality. The main therapeutic goal of gallstone ileus is a relief of intestinal obstruction by evacuating the gallstones.Conclusion: Because of nonspecific signs and symptoms, the diagnosis of gallstone ileus is often delayed. It is mostly an incidental finding during abdominal procedures. Therefore, it should be considered in patients presenting with bowel obstruction and known gallstone disease.
Co-Authors Afrizal Tri Heryadi Eri, Rakhmawati Susetyaning Hari Wujoso Kusumaningrum, Sulistyani Nindya Wiharjanto, Dorothy Eugene Putro, Prasetyo Sarwono WIDIASTUTI -