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All Journal International Archives of Medical Sciences and Public Health International Archives of Medical Sciences and Public Health FARMASAINKES
Septiana, Lilik
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Religion Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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TINGKAT PENGETAHUAN DAN SIKAP MASYARAKAT TENTANG ANTIBIOTIK DI KELURAHAN MANDAILING KECAMATAN TEBING TINGGI KOTA Septiana, Lilik; Hafizhatul Abadi; Sipahutar, Rizki Anjani; Zulmai Rani
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 4 No. 2 (2025): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v4i2.4006

Abstract

Antibiotics are a group of compounds, both natural and synthetic, that have the effect of suppressing or stopping a biochemical process in an organism, especially in the process of infection by bacteria. This study only describes the object of the study by collecting questionnaire data from the community to determine the knowledge and attitudes of the community about antibiotics in Mandailing Village, Tebing Tinggi District, City. The results of the study obtained from univariate analysis found that the level of knowledge of respondents in the high category was 34 people (35.79%), in the moderate category was 47 people (49.47%), and in the low category was 14 people (14.74%). The total score was 680. At the level of attitude, respondents in the good category were 21 people (22.10%), in the sufficient category were 22 people (23.16%), and in the less category were 52 people (54.74%); the total score was 529. At the level of community knowledge, it was in the moderate category (71.57%), community attitudes were in the less category (55.68%), and there was a relationship between age, education, and occupation with the level of knowledge; there was a relationship between education and occupation with community attitudes about antibiotics; there was a relationship between the level of knowledge and community attitudes about antibiotics in the use of antibiotics in Mandailing Village, Tebing Tinggi District, City.
Activity Test of Neem Leaf (Azadirachta Indica A. Juss) Anti-Dambry Shampoo on Fungus (Malassezia Furfur) Ginting, Mandike; Septiana, Lilik; Br. Ginting, Grace Anastasia
International Archives of Medical Sciences and Public Health Vol. 4 No. 2 (2023)
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i2.636

Abstract

Background; Dandruff is a disorder in the form of excessive flaking of dead skin on the scalp, sometimes accompanied by itching and inflammation. One of the causes of dandruff is the Malassezia furfur fungus. Neem leaves contain the main active ingredients of neem, namely azadirachtin, meliantriol, nimbin, nimbidin and salanin, substances that are known to be effective as insecticides. Objective; The aim of the study was to determine the formulation of anti-dandruff shampoo preparations of ethanol extract of neem leaves (Azadirachta indica A. Juss) and Activity Test against Fungus (Malassezia furfur). Method; The research method was experimental, which included taking plants, making simplicia, formula for neem leaf extract shampoo (2%, 4%, 6% and 8%), evaluating preparations and testing antifungal activity. Results; The results of the study were based on organoleptic tests, the preparations were white and brown in color, had a distinctive neem aroma and were viscous in shape; there is no coarse grain in the preparation; pH of preparations F0 (6.0), F1 (5.5), F2 (5.3), F3 (5.3) and F4 (5.2); foam height tests F0 (8 cm), F1 (8.5 cm), F2 (8.7 cm), F3 (9 cm) and F4 (9.5 cm); there is no itching, redness and swelling on the skin of the volunteers; stability test does not change color, aroma and shape of the preparation; antifungal test preparations F0 (0 cm), F1 (11.65 cm), F2 (12.73 cm), F3 (12.86 cm), F4 (13.61 cm) and K+ (22.8 cm). Conclusion; The conclusion of the research is that the ethanol extract of neem leaves (Azadirachta indica A. Juss) can be formulated as a shampoo that meets the requirements for physical evaluation and inhibits the growth of fungus (Malassezia furfur) at a concentration of 8% (13.61 mm) best.
Activity Test of Neem Leaf (Azadirachta Indica A. Juss) Anti-Dambry Shampoo on Fungus (Malassezia Furfur) Ginting, Mandike; Septiana, Lilik; Br. Ginting, Grace Anastasia
International Archives of Medical Sciences and Public Health Vol. 4 No. 2 (2023)
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i2.636

Abstract

Background; Dandruff is a disorder in the form of excessive flaking of dead skin on the scalp, sometimes accompanied by itching and inflammation. One of the causes of dandruff is the Malassezia furfur fungus. Neem leaves contain the main active ingredients of neem, namely azadirachtin, meliantriol, nimbin, nimbidin and salanin, substances that are known to be effective as insecticides. Objective; The aim of the study was to determine the formulation of anti-dandruff shampoo preparations of ethanol extract of neem leaves (Azadirachta indica A. Juss) and Activity Test against Fungus (Malassezia furfur). Method; The research method was experimental, which included taking plants, making simplicia, formula for neem leaf extract shampoo (2%, 4%, 6% and 8%), evaluating preparations and testing antifungal activity. Results; The results of the study were based on organoleptic tests, the preparations were white and brown in color, had a distinctive neem aroma and were viscous in shape; there is no coarse grain in the preparation; pH of preparations F0 (6.0), F1 (5.5), F2 (5.3), F3 (5.3) and F4 (5.2); foam height tests F0 (8 cm), F1 (8.5 cm), F2 (8.7 cm), F3 (9 cm) and F4 (9.5 cm); there is no itching, redness and swelling on the skin of the volunteers; stability test does not change color, aroma and shape of the preparation; antifungal test preparations F0 (0 cm), F1 (11.65 cm), F2 (12.73 cm), F3 (12.86 cm), F4 (13.61 cm) and K+ (22.8 cm). Conclusion; The conclusion of the research is that the ethanol extract of neem leaves (Azadirachta indica A. Juss) can be formulated as a shampoo that meets the requirements for physical evaluation and inhibits the growth of fungus (Malassezia furfur) at a concentration of 8% (13.61 mm) best.
EVALUASI PENGGUNAAN OBAT ANTIBIOTIK PADA PASIEN PNEUMONIA DENGAN METODE GYSSENS DI INSTALASI RAWAT INAP DI RUMAH SAKIT HAJI MEDAN TAHUN 2024 Septiana, Lilik; Rani, Zulmai
JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 5 No. 1 (2025): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v5i1.5086

Abstract

Pneumonia adalah suatu peradangan paru yang disebabkan oleh bakteri sehingga salah satu terapi yang diberikan yaitu antibiotik. Penggunaan antibiotik yang tidak rasional menyebabkan pengobatan kurang efektif. Pemilihan dan penggunaan terapi antibiotik yang bijak pada pasien pneumonia akan menentukan keberhasilan pengobatan dan menghindari terjadinya resistensi bakteri. Metode Gyssens adalah standar untuk evaluasi kualitatif dalam meresepkan antibiotik dengan kelebihan terperinci/jelas dan dapat mengevaluasi penggunaan antibiotik secara kualitatif lebih tepat sehingga akan mencegah terjadinya antibiotik resisten. Tujuan dari penelitian ini adalah mengevaluasi penggunaan antibiotik pada pasien pneumonia menggunakan metode gyssens di rumah sakit haji Medan. Penelitian ini merupakan penelitian deskriptif dengan pengambilan sampel secara purposive sampling, yaitu pemilihan sampel berdasarkan ciri-ciri yang sesuai kriteria inklusi. Sampel yang digunakan yaitu data rekam medik pasien yang terdiagnosa pneumonia dan mendapatkan pengobatan antibiotik, kemudian data dianalisis menggunakan alur diagram Gyssens. Penelitian ini dilakukan pada 89 pasien yang memenuhi kriteria inklusi. Berdasarkan hasil penelitian penggunaan antibiotik pada pasien pneumonia dengan menggunakan metode gyssens di rumah sakit haji Medan tahun 2024 terdapat sebanyak 61,8% penggunaan antibiotik yang rasional.
Co-Authors Abadi, Hafizhatul Br. Ginting, Grace Anastasia Ginting, Mandike Sipahutar, Rizki Anjani Zulmai Rani