Santy Irene Putri
Politeknik Kesehatan Wira Husada Nusantara Malang

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Pepe leaf extract (gymnema sylvestre) to reduce blood glucose levels in pregnant women with a history of gestational diabetes mellitus Retno Dewi Prisusanti; Santy Irene Putri
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 11 (2026): Volume 8 Number 11
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i11.1581

Abstract

Background: Gestational diabetes mellitus (GDM) is a glucose intolerance disorder that appears during pregnancy and has the potential to cause complications in both mother and fetus. The use of pharmacological therapies such as insulin is often constrained by safety limitations in pregnant women, so a safe and effective adjuvant alternative is needed. Gymnema sylvestre (pepe leaf) is known to have hypoglycemic effects through the mechanism of inhibiting glucose absorption, stimulating β pancreatic cell function, and increasing peripheral glucose utilization. Purpose: To evaluate the effectiveness of pepe leaf extract (gymnema sylvestre) in reducing blood glucose levels in pregnant women with a history of gestational diabetes mellitus. Method: A quasi-experiment with a pretest-posttest control group design. The study took place from August 2025 in Community Health Center Bumiaji, Batu Malang. The independent variables studied were effectiveness of pepe leaf extract (Gymnema sylvestre), while the dependent variable was blood glucose levels. Using purposive sampling and lameshow formula 60 participants were selected devided into two group, who meet specific inclusion and exclusion criteria. The analysis proceeded with a univariate test to determine the frequency distribution of respondents characteristics, followed by bivariate analysis using paired t-test. Results: Before the intervention, the mean fasting blood glucose (FBG) levels were 129.1±6.9 mg/dL in the treatment group and 124.6±4.7 mg/dL in the control group. After the intervention, mean FBG decreased to 117.5±6.2 mg/dL in the treatment group and 113.0±5.4 mg/dL in the control group. The post-intervention difference between groups was statistically significant (p<0.001), demonstrating a significant effect of the intervention on reducing fasting blood glucose levels. Conclusion: Showed that the intervention provided was effective in reducing fasting blood glucose (GDP) levels in pregnant women with a history of gestational diabetes.
Deteksi Menuju Aksi: Penguatan Literasi Informasi Kesehatan tentang Artritis Gout melalui Skrining dan Konseling Terintegrasi Santy Irene Putri; Aris Widiyanto; Isnaini Qoriatul Fadhilah; Rizki Aqsyari D; Arie Jefry Ka&#039;arayeno
Jurnal Medika: Medika in progres
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/mykr4w34

Abstract

Hyperuricemia is a condition of increased uric acid levels in the blood which plays an important role as an etiological factor in the occurrence of gout. Currently, gout is a public health problem that is increasing due to changes in lifestyle, consumption patterns, and low public knowledge about risk factors and their prevention. Misconceptions, such as the assumption that all joint pain is caused by gout and restricting the consumption of certain vegetables without scientific basis, are still widely found in society. This community service activity aims to increase public knowledge and awareness about gout through uric acid levels checks and the provision of health counseling. The activity was held in Mojorejo, Sragen, Central Java. The method used includes checking uric acid levels using a simple test tool followed by individual and group counseling. Counseling materials include the definition of gout, etiology, clinical manifestations, disease impact, prevention efforts, gout management, and traditional medicine. Evaluation was carried out through observation of active community participation and questions and answers during the counseling process. The results of the activity show high public enthusiasm, increased understanding of gout, and increased awareness to conduct routine health check-ups at health care facilities. This activity is expected to contribute to the promotive and preventive efforts of gout at the community level.