Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Andalas Jurnal Ilmu Kesehatan Indonesia (JIKSI)
Ramadhan, Mario Arya
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Unveiling the Antibacterial Activity of Petai Seed Ethanol Extract (Parkia speciosa Hassk) with the Kirby-Bauer Method Alioes, Yustini; Efendi, Altio; Ramadhan, Mario Arya
Andalas Journal of Health Vol. 13 No. 2 (2024): July 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i2.2420

Abstract

The increasing number of antibiotic resistance cases have to seek alternative treatments, including the petai plant (Parkia speciosa Hassk). Petai seeds primarily contain chemical compounds such as tannins, saponins, alkaloids, and flavonoids, which are known for their antibacterial properties. Objective: To determined the antibacterial activity of petai seed ethanol extract (P. speciosa Hassk) against Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella typhi. Methods: This experiment used the Kirby-Bauer Method. Petai seeds were extracted with ethanol using maceration techniques, and the viscous extract was dissolved into concentrations of 25%, 50%, 75%, and 100%. Screening paper soaked in the extract was placed on agar plates inoculated with the test bacteria, and the plates were incubated for 24 hours. The inhibition zones were measured with a caliper, and the data were analyzed statistically. Results: The study found that the ethanol extract of petai seeds exhibited moderate antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and weak antibacterial activity against Salmonella typhi. Conclusion: Increasing the concentration of the extract significantly enhanced its antibacterial effect against Staphylococcus aureus and Pseudomonas aeruginosa, indicating that petai seed ethanol extract could be a potential alternative treatment for bacterial infections.Keywords:  antibacterial, extract ethanol, Kirby-Bauer method, petai seed
Daya Hambat Ekstrak Etanol Biji Petai terhadap Bakteri Pseudomonas aeruginosa Ramadhan, Mario Arya; Alioes , Yustini; Eka Putra , Andani; Suharti , Netti; Aliska, Gestina; Hasmiwati, Hasmiwati
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 2 (2025): Juni 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i2.1402

Abstract

Latar Belakang: Pseudomonas aeruginosa adalah penyebab umum dari infeksi nosokomial. Meningkatnya angka Multidrug resistant Pseudomonas aeruginosa menyebabkan terjadinya peningkatan biaya pengobatan sehingga diperlukan pengobatan alternatif murah dan efektif, contohnya adalah tanaman petai (Parkia speciosa Hassk.). Biji petai (Parkia speciosa Hassk.) berpotensi untuk menjadi obat alternatif terhadap penyakit yang ditimbulkan Pseudomonas aeruginosa. Objektif: Penelitian ini bertujuan untuk mengetahui perbedaan diameter zona hambat pada konsentrasi (25%, 50%, 75%, dan 100%) ekstrak etanol biji petai (Parkia speciosa Hassk.) terhadap bakteri Pseudomonas aeruginosa. Metode: Penelitian ini berupa penelitian eksperimental menggunakan metode difusi cakram. Biji petai diekstraksi menggunakan teknik maserasi dengan pelarut etanol. Ekstrak kental dilarutkan menjadi konsentrasi 25%, 50%, 75%, dan 100%. Kertas saring yang telah direndam di dalam konsentrasi uji diletakkan di atas media agar yang telah ditanami bakteri Pseudomonas aeruginosa. Cawan perti selanjutnya diinkubasi selama 24 jam. Diameter zona hambat diukur menggunakan jangka sorong. Data hasil penelitian dianalisis secara statistik. Hasil: Hasil penelitian menunjukkan rerata diameter zona hambat tiap konsentrasi secara berurutan adalah 2,20 mm (25%), 6,40 mm (50%), 7,05 mm (75%), dan 7,60 mm (100%). Kesimpulan: Terdapat perbedaan diameter yang signifikan antara konsentrasi 25% ekstrak biji petai dengan konsentrasi masing-masing 50%, 75%, dan 100% terhadap pertumbuhan bakteri Pseudomonas aeruginosa.
Co-Authors Alioes , Yustini Andani Eka Putra Efendi, Altio Gestina Aliska Hasmiwati Suharti , Netti Yustini Alioes