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Restiawati, Nawang
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media

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Phytochemical Compound, Antioxidant and Antibacterial Properties of Sargassum sp. Extracts from Pahawang Island, Lampung Province Khairani, Iffa Afiqa; Istiadi, Khaerunissa Anbar; Restiawati, Nawang
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 11, No 1: Jurnal Pembelajaran Dan Biologi Nukleus March 2025
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v11i1.6558

Abstract

Pahawang Island, located in Lampung Bay, has a variety of potential natural resources, one of which is macroalgae. One of the abundant brown macroalgae is Sargassum sp., with phytochemical components (flavonoids, steroids, tannins, and glycosides) that have potential as antioxidants, antibacterial, antitumor, anticancer, antifouling, and others. Sargassum sp. from Lampung waters, especially Pahawang Island still lacks scientific studies on its bioactive content and properties. This study aims to examine the phytochemical compounds (qualitatively and quantitatively), antioxidant activity (DPPH method) and antibacterial potential of Sargassum sp. extract (MIC/MBC method) against Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The results of phytochemical assay  showed that Sargassum sp. extract contained phenolic compounds, flavonoids, tannins, and saponins. Quantification results on total phenolic content were 0.56 mgGAE/g extract, total tannins were 4.27 mgTAE/g extract, total flavonoids were 14.19 mgQE/g extract, and total saponins were 5.54 %. Sargassum sp. extract classified as a very weak antioxidant with IC50 value of 964.10 ppm, and moderate antibacterial activity at a concentration of MIC/MBC 250/250 ppm against B. subtilis, E. coli, P. aeruginosa, and S. aureus
Co-Authors Iffa Afiqa Khairani Khaerunissa Anbar Istiadi