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All Journal Buletin Ilmiah Nagari Membangun Andalas obstetrics and gynecology journal
Puja Agung Antonius
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Nursing Public Health Veterinary Other

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Adjuvant Chemotherapy For FIGO Stage IIA2 Cervical Cancer : A Case Report Heryanto, Deni; Syamel Muhammad; Puja Agung Antonius
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.792-800.2024

Abstract

Background : Cervical cancer ranked as the third most prevalent cancer among women. This case report is to examine the current status of adjuvant chemotherapy in the treatment of early-stage cervical cancer as documented in the literature. Currently, there is no established evidence supporting the therapeutic efficacy of adjuvant chemotherapy as a standalone treatment following radical hysterectomy surgery. Nevertheless, some literature recommend the use of adjuvant radiotherapy (AR), adjuvant chemotherapy (AC), or concomitant chemoradiotherapy (CCRT) as the standard adjuvant therapies for early-stage cervical cancer following radical hysterectomy with positive prognostic factor. Case report: A 53-year-old female was diagnosed with stage IIA2 in April 2021. The histology type was determined to be keratinized squamous cell carcinoma, moderately well differentiated. The patient underwent a radical hysterectomy, resulting in the acquisition of uterine and cervical tissue measuring 11x11×6 cm. The histology results revealed moderately to poorly differentiated keratinizing squamous cell carcinoma, with no invasion of the parametrium or pelvic lymph nodes with vaginal cutting margin is free of tumor growth, but lymph vascular space invasion was present. Subsequently, adjuvant chemotherapy was administered using carboplatin (AUC 5) and paclitaxel for a total of 6 cycles. After 2 years with follow-up with CT-Scan examination in April 2023 confirmed the absence of any residual mass. Conclusion: A radical hysterectomy combined with adjuvant chemotherapy has been shown to reduce the chance of recurrence or progressiveness of the disease, in which this patient did not experience a recurrence after two years of treatment  
Edukasi Interaktif untuk Meningkatkan Pengetahuan Ibu Hamil tentang Komplikasi Kehamilan dan Pencegahan Stunting di Puskesmas Pauh Padang yusrawati; Bobby Indra Utama; Vaulinne Basyir; Dovy Djanas; Rina Gustuti; Defrin; Nelvianti Nelson; Syamel Muhammad; Puja Agung Antonius; Sukri Rahman; Mela Aryati; Ardiles; Danil Armand; Zeino Fridsto; Subhan Arif Rahman; Aswin Boy Pratama; Dian Noviyanti; Edward Hariyadi; Irfan Kurnia; Rena Afri Ningsih; Rezi Liawati; Yesi Anggriani; Sakina Munira; Sara Uzlifah
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 9 No. 1 (2026)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v9i1.841

Abstract

Maternal mortality and stunting remain major public health challenges in Indonesia, largely due to limited early detection of pregnancy complications and low maternal health literacy during the First 1000 Days of Life. Strengthening maternal knowledge through structured education is essential to improve pregnancy outcomes. This community service program aimed to enhance pregnant women’s knowledge of pregnancy danger signs, completion of six antenatal care (ANC) visits, anemia prevention, balanced nutrition, and early stunting prevention. A community-based participatory approach using a service-learning model was implemented among 39 pregnant women at Pauh Primary Health Center, Padang. Educational activities were conducted through interactive lectures, group discussions, and question-and-answer sessions. Knowledge was assessed using pre-test and post-test instruments and analyzed with a paired t-test. The results showed a significant increase in mean knowledge scores from 77.98 ± 16.26 to 86.60 ± 11.18 (p = 0.0002). The proportion of participants with “good” knowledge increased from 66.6% to 76.6%, while those with “poor” knowledge decreased substantially. These findings indicate that interactive and structured maternal health education effectively improves understanding of pregnancy complications and stunting prevention. Continuous implementation through routine maternal classes and stronger family involvement is recommended to sustain behavioral changes and improve maternal and child health outcomes.
Co-Authors Ardiles Aswin Boy Pratama Bobby Indra Utama Danil Armand Defrin Deni Heryanto, Deni Dian Noviyanti Dovy Djanas Edward Hariyadi Irfan Kurnia Mela Aryati Nelvianti Nelson Rena Afri Ningsih Rezi Liawati Rina Gustuti Sakina Munira Sara Uzlifah Subhan Arif Rahman Sukri Rahman Syamel Muhammad Vaulinne Basyir Yesi Anggriani yusrawati Zeino Fridsto