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All Journal Buletin Ilmiah Nagari Membangun Andalas obstetrics and gynecology journal
Dovy Djanas
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Nursing Public Health Veterinary Other

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Comparison of Detection Methods for Premature Rupture of Membranes: IGFBP-1 Immunoassay Test vs. Nitrazine Test Vekky Tria Novanda; Dovy Djanas; Ferdinal Ferry
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 2 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.2.231-240.2025

Abstract

Objective: This study aimed to compare the diagnostic accuracy of the Insulin-like Growth Factor Binding Protein-1 (IGFBP-1) immunoassay test with the conventional Nitrazine test in detecting Premature Rupture of Membranes (PROM). Method: A diagnostic cross-sectional study was conducted as part of a multicenter study in 19 centers. It involved 40 pregnant women (20 with PROM and 20 without PROM) between 28–36 weeks of gestation at Dr. M. Djamil Hospital, Padang. The IGFBP-1 immunoassay (Actim PROM) and Nitrazine tests were performed using posterior vaginal fornix swabs. PROM diagnosis was confirmed by speculum examination. Data analysis included ROC curves, Youden’s Index, and AUC using SPSS v27. Result: The IGFBP-1 immunoassay yielded 100% sensitivity and 100% positivity in PROM cases. The Nitrazine test showed 75% sensitivity with 4 false negatives. IGFBP-1 provided more accurate results, was unaffected by vaginal bleeding or infections, but was more costly and required immediate handling. Conclusion: IGFBP-1 immunoassay demonstrates superior sensitivity and specificity compared to the Nitrazine test for PROM diagnosis. It is particularly advantageous in cases with unclear symptoms or contamination, supporting its use as a more reliable diagnostic tool in obstetric care.
Peningkatan Pengetahuan Ibu Hamil tentang Komplikasi Kehamilan dan Pencegahan Stunting melalui Edukasi Interaktif di Puskesmas Pauh Kota Padang: Improving Pregnant Women’s Knowledge of Pregnancy Complications and Stunting Prevention through Interactive Education at Pauh Primary Health Center, Padang yusrawati; Bobby Indra Utama; Vaulinne Basyir; Dovy Djanas; Rina Gustuti; Defrin; Nelvianti Nelson; Syamel Muhammad; Puja Agung Antonius; Sukri Rahman; Mela Aryati; Ardiles; Danil Armand; Zeino Fridsto; Subhan Arif Rahman; Aswin Boy Pratama; Dian Noviyanti; Edward Hariyadi; Irfan Kurnia; Rena Afri Ningsih; Rezi Liawati; Yesi Anggriani; Sakina Munira; Sara Uzlifah
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 9 No. 1 (2026)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v9i1.841

Abstract

Maternal mortality and stunting remain major public health challenges in Indonesia, largely due to limited early detection of pregnancy complications and low maternal health literacy during the First 1000 Days of Life. Strengthening maternal knowledge through structured education is essential to improve pregnancy outcomes. This community service program aimed to enhance pregnant women’s knowledge of pregnancy danger signs, completion of six antenatal care (ANC) visits, anemia prevention, balanced nutrition, and early stunting prevention. A community-based participatory approach using a service-learning model was implemented among 39 pregnant women at Pauh Primary Health Center, Padang. Educational activities were conducted through interactive lectures, group discussions, and question-and-answer sessions. Knowledge was assessed using pre-test and post-test instruments and analyzed with a paired t-test. The results showed a significant increase in mean knowledge scores from 77.98 ± 16.26 to 86.60 ± 11.18 (p = 0.0002). The proportion of participants with “good” knowledge increased from 66.6% to 76.6%, while those with “poor” knowledge decreased substantially. These findings indicate that interactive and structured maternal health education effectively improves understanding of pregnancy complications and stunting prevention. Continuous implementation through routine maternal classes and stronger family involvement is recommended to sustain behavioral changes and improve maternal and child health outcomes.
Co-Authors Ardiles Aswin Boy Pratama Bobby Indra Utama Danil Armand Defrin Dian Noviyanti Edward Hariyadi Ferdinal Ferry Irfan Kurnia Mela Aryati Nelvianti Nelson Puja Agung Antonius Rena Afri Ningsih Rezi Liawati Rina Gustuti Sakina Munira Sara Uzlifah Subhan Arif Rahman Sukri Rahman Syamel Muhammad Vaulinne Basyir Vekky Tria Novanda Yesi Anggriani yusrawati Zeino Fridsto