Septiyanti, Windy
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Oral corticosteroids (OCS), inhaled corticosteroids (ICS), short acting β-2 agonists (SABA), ICS/long acting β-2 agonists (LABA) treatment in pregnancy with asthma: a review Septiyanti, Windy; Ramez Abdullah; Wahda Aqiedaty; Winda Kirana Ade Putri; Yuli Edy Saputra
Indonesian Journal of Pharmacology and Therapy Vol 6 No 1 (2025)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.5902

Abstract

Asthma is one of the common pulmonary disorders that can complicate pregnancy. Therefore, managing asthma is crucial for pregnant women's health and the well-being of the embryo. As consequence, it is important to evaluate the effectiveness and integrity of treatment for this usual therapy in expectant mothers with asthma. This review aimed to analyze the efficacy and safety of OCS, ICS, SABA, and ICS/LABA treatment in pregnancy with asthma. The articles were researched from PubMed, Scopus, and Science Direct as literature resources and selection of process based on inclusion criteria. The use of OCS, ICS, SABA, ICS/LABA were safe for pregnancy with asthma, although there are some side effects. In conclusion, the regiment therapy of asthma in asmathic pregnant women is similar to general treatment for asthmatic.
Adverse effects of fentanyl/midazolam among patients of intensive care unit (ICU): a narrative review Septiyanti, Windy; Puspita Sari, Ika; Murti Andayani, Tri
Indonesian Journal of Pharmacology and Therapy Vol 5 No 2 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.11232

Abstract

Patients of intensive care unit (ICU) have a complicated condition due to disease, comorbid, and other risk factors. Some ICU patients need to get an invasive process to reduce pain, anxiety, and support their condition. During an invasive process, including mechanical ventilation which causes pain or anxiety, the patient is givensedative and analgesic agents to support the procedure and reduce the patient’s pain and anxiety. However, the use of fentanyl/midazolam has the potential to cause adverse effects, for instance, hypotension, hypoxia, and delirium in several ICU patients. Several risk factors that can lead to adverse effects are aging, obesity, underlying cardiac disease, and the amount of dosage. Therefore, it is essential to recognize the risk factors and monitor the use of fentanyl/midazolam to prevent the worsening condition of patients.