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All Journal HAYATI Journal of Biosciences Jurnal Kesehatan Mahardika
farah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Literature Review: Peluang Dan Tantangan Penggunaan Keceerdasan Buatan Dalam Meningkatkan Pelayanan Farmasi Klinis farah; Putri Auliya Serawaidi, Nadya
Jurnal Kesehatan Mahardika Vol. 12 No. 1 (2025): Jurnal Kesehatan Mahardika
Publisher : LPPM ITEKES Mahardika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54867/jkm.v12i1.240

Abstract

Artificial Intelligence offers opportunities has to optimize clinical pharmacy services in hospitals or other pharmaceutical services. AI can assist clinical pharmacists in the field of clinical pharmacy such as prescription review, therapeutic drug monitoring, monitoring of drug adverse effects, and providing drug information services. The aim of this literature review is to analyze and summarize the opportunities and challenges of AI in supporting clinical pharmacy services. This study uses a literature review method with a qualitative research approach. The selected journal criteria are journals published between 2015 and 2025 and are fully accessible. From the review, eight journals were found that met the criteria for analysis. The result of this literature review indicate that AI can enhance the quality and effectiveness of clinical pharmacy services. The development of AI in clinical pharmacy has just begun, and there are several challenges that need to be addressed, such as data bias, data security, the lack of regulations and ethics, and resistance to AI usage. Evaluation and collaboration with other healthcare professionals and technology experts are needed to improve AI-based clinical pharmacy services.
The Potential Use of Wood Vinegar as an Alternative Inhibitor to Enhance 5-Aminolevulinic Acid Production by Bacillus paramycoides Farah; Fauzi, Ahmad; Monconegoro, Dicky Adihayyu; Nurani, Diana; Abraham, Silva
HAYATI Journal of Biosciences Vol. 32 No. 4 (2025): July 2025
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.32.4.850-858

Abstract

The expensive production of 5-aminolevulinic acid (ALA) as a plant growth stimulator led to an attempt to get an alternative substrate to reduce the production cost. Levulinic acid is the inhibitor of ALA dehydratase in ALA production. Wood vinegar, a liquid gas produced from wood combustion in airtight conditions, is known to contain 12-17 mM of levulinic acid. This study aims to explore the use of wood vinegar as a potential substitute for levulinic acid in the extracellular production of ALA by bacteria identified as Bacillus paramycoides through 16S rRNA sequence analysis. Adding precursor and inhibitor glutamate and 1% wood vinegar increased the ALA production to 174.3 µM, while the combination of glutamate and levulinic acid raised the ALA production to 179.9 µM. This study confirmed that wood vinegar can enhance the concentration of ALA and potentially substitute levulinic acid as an inhibitor in ALA production.
Co-Authors ABRAHAM, SILVA DIANA NURANI Fauzi Ahmad Muda Monconegoro, Dicky Adihayyu Nadya Putri Auliya Serawaidi