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All Journal Jurnal Biologi Tropis Jurnal Kesehatan Tambusai Jurnal Wicara Desa
Alfhina, Luluk
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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ARTIKEL REVIEW : IDENTIFIKASI SENYAWA FLAVONOID PADA SPONS CALLYSPONGIA SP. SEBAGAI ANTIBAKTERI DALAM PENGEMBANGAN PRODUK FARMASI Syafitri Dwiyanti, Dhea; Qotrunnada, Baiq Citra Azzahra; Lestari, Dinda Ayu; A’yun, Faolananda Qurrota; Agustiani, Eti; Alfhina, Luluk; Sunarwidh, Anggit Listyacahyani
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.38294

Abstract

Sebagai salah satu negara kepulauan terbesar di dunia, Indonesia memiliki kekayaan kelautan yang sangat potensial, termasuk berbagai biota laut seperti spons. Spons laut yang diketahui mengandung metabolit sekunder bernilai tinggi adalah Callyspongia sp. Spons ini mengandung beragam senyawa bioaktif yang berasal dari metabolit primer dan sekunder, termasuk alkaloid, asam lemak, peptida, flavonoid, nukleosida, steroid, poliasetilen, dan terpenoid. Salah satu senyawa metabolit sekunder dari Callyspongia sp. yang memiliki banyak efek farmakologis terutama sebagai antibakteri yaitu flavonoid. Aktivitas antibakterinya menjadikannya berpotensi besar untuk pengembangan obat-obatan di masa depan. Tujuan penelitian ini untuk mengetahui cara isolasi dan identifikasi senyawa flavonoid dari spons Callyspongia, menguji aktivitas antibakterinya, dan mengeksplorasi penggunaannya dalam produk farmasi. Penelitian ini menggunakan metode literature review yaitu mengumpulkan data - data hasil penelitian sebelumnya dari berbagai sumber bacaan seperti jurnal yang kemudian dianalisis dan dirangkum. Berdasarkan hasil penelitian, dalam spons Callyspongia sp. ditemukan senyawa alkaloid, tanin, terpenoid, dan flavonid. Isolasi serta identifikasi flavonoid dari Callyspongia dapat dilakukan dengan uji warna, kromatografi lapis tipis dan juga bisa menggunakan metode kromatografi cairan vakum. Callyspongia sp. menunjukkan penghambatan pertumbuhan bakteri maksimal pada berbagai jenis bakteri, seperti Shigella, Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Streptococcus pyogenes dan  S. mutans. Aktivitas antibakteri yang terdapat dalam Callyspongia sp. tersebut dapat dikembangkan menjadi suatu produk farmasi seperti krim dan salep.  
PENDAMPINGAN PEMANFAATAN LIMBAH BONGGOL JAGUNG (JANGGEL) SEBAGAI MEDIA TANAM JAMUR DI DESA DARA KUNCI, SAMBELIA, LOMBOK TIMUR Jurnal Wicara; Abidin, Muhammad; Astiti, Ida Ayu Made Widya; Alfhina, Luluk; Meilieana, Eca; Putra, Lalu; Hidayani, Nurul; Adiat, Dina; Rizal Abidin, Muhammad; Prayanto, Muhammad; Susilawati, Desi; Ahfal, Syahrul
Jurnal Wicara Vol 3 No 5 (2025): Jurnal Wicara Desa
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/2161n081

Abstract

The majority of the residents in Dara Kunci Village rely on the agricultural sector. Maize serves as the primary commodity in alignment with the national food security program. However, only the kernels are utilized, while the cobs remain as agricultural waste. In fact, maize cobs contain substances that can accelerate the growth of mushrooms. Therefore, the Community Service Program (KKN) team from the University of Mataram (UNRAM) initiated a training program on the utilization of maize cobs as mushroom cultivation media, aiming to reduce agricultural waste and develop economically valuable products. Furthermore, it is expected that the people of Dara Kunci Village will be able to implement this mushroom cultivation independently. The applied methodology consisted of two stages, namely surveys and observations, as well as training. The activities were carried out in accordance with the proposed methods. During the training, all stages of mushroom cultivation using maize cobs were explained in detail, including critical aspects that required particular attention. Prior to the training, the team had already cultivated mushrooms as a demonstrative example, proving that this waste utilization is indeed beneficial. In doing so, the team was able to highlight factors that may inhibit mushroom production and provide appropriate solutions to address such issues. Moreover, following the training, several community members successfully cultivated mushrooms within the expected growth period.
Problem Profile of Drugs (DRPs) in Antidiabetic Therapy for Type 2 Diabetes Mellitus Patients in The Inpatient Ward Alfhina, Luluk; Harahap, Herpan Syafii; Alaydrus, Raisya Hasina
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11571

Abstract

The occurrence of type 2 diabetes mellitus keeps rising worldwide each year, and this includes Indonesia. Individuals with type 2 diabetes mellitus frequently encounter Drug-Related Problems (DRPs) due to multiple medications resulting from related health issues. Thus, recognizing DRPs is essential to enhance treatment success. The Mataram City Regional General Hospital stands out as one of the hospitals with the most significant number of type 2 diabetes mellitus cases each year from 2021 to 2023, showing an increase of 18.81%. The objective of this study was to analyze the profile of DRPs (Drug-Related Problems) in antidiabetic therapy among type 2 diabetes mellitus patients in the inpatient ward of Mataram City General Hospital during the period of April 2025. Data gathering was performed retrospectively by reviewing medical documents and conducting patient interviews. The medical documents were examined using the Cipolle classification, and the findings were illustrated in a diagram format with Microsoft Excel. The findings indicated that drug-related issues (DRPs) were present in hospitalized patients with type 2 diabetes mellitus at the Mataram City Regional General Hospital in April 2025. Among the 55 diabetes patients, 7 were found to have DRPs (12.72%), with DRPs manifesting as indications lacking medication (9.09%) and medications prescribed without indications (3.64%).
Co-Authors Abidin, Muhammad Adiat, Dina Agustiani, Eti Ahfal, Syahrul Alaydrus, Raisya Hasina Astiti, Ida Ayu Made Widya A’yun, Faolananda Qurrota Desi Susilawati, Desi Herpan Syafii Harahap Jurnal Wicara Lestari, Dinda Ayu Meilieana, Eca Nurul Hidayani Prayanto, Muhammad Putra, Lalu Qotrunnada, Baiq Citra Azzahra Rizal Abidin, Muhammad Sunarwidh, Anggit Listyacahyani Syafitri Dwiyanti, Dhea