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All Journal Bionature SAINSMAT: Jurnal Ilmiah Ilmu Pengetahuan Alam
A. Mu’nisa
Universitas Negeri Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Antioxidant Activities and Bioactive Compound in The Extract of Lobophytum sp. A. Mu’nisa
Bionature Vol. 24 No. 1 (2023): April 2023
Publisher : Jurusan Biologi Universitas Negeri Makassar

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This study is a descriptive exploratory research that aims to know the activity of soft coral Lobophytum sp. extractas an antioxidant. Sample extraction was done by maceration using methanol. Viscous extract obtained was thenpartitioned using n-hexane until gained methanol and n-hexane fraction. The chemical compositions of themethanol extract of Lobophytum sp were investigated using Gas chromatography-Mass spectrometry. The yieldresult of soft coral Lobophytum sp. extract is 2,59%. The weight of extract partition result were methanol fraction8,76 g and n-hexane fraction 1,02 g. Antioxidant activity test using the 2,2-Diphenyl-1-picrylhydrazyl (DPPH)assay. Ascorbic acid was also used as positive antioxidant control. The percentage of inhibition and IC50 weremeasured. Antioxidant activity test which gains the best antioxidant activity is methanol fraction then followed byn-hexane fraction, both showed DPPH free radical 50% can be inhibited the activity with IC50 rate in a sequence16,93 ppm and 30,93 ppm. GC-MS analysis, 50 kinds of chemical composition are identified in the Lobophytumsp. The results showed that the soft coral extracts of Lobophytum sp. has antioxidant activity.
Effectiveness of Acalypha Indica Leaf Extract and Plant Imperata Cylindrica on Glucose Levels of Mencit (Mus musculus L) Hyperglycemia A. Mu’nisa; Alimuddin Ali; M. Junda; A. Muflihunna; Balqis Dinarty Jamaluddin; Maulyda Awwaliah P
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol. 9 No. 1 (2020): Volume 9 Nomor 1 (Maret 2021)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

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This study aims to determine the effectiveness of the extract of Acalypha indica and plant Imperata cylindrica on glucose levels of mice (Mus musculus L) hyperglycemia. This study used 40 male ICR strain male mice which were divided into 8 treatment groups, namely normal mice group, hyperglycemia mice group, and mice group by giving methanol extract Acalypha indica and Imperata cylindrical plants at each dose of 150 and 250 mg / Kg bb. The results showed that the extract of the leaves of Acalypha indica and Imperata cylindrica plants showed a decrease in blood glucose levels of mice by 47-49%. The conclusion of this research is the effectiveness of the methanol extract of Acalypha indica and the Imperata cylindrical plant influences the decrease in blood glucose levels in hyperglycemia mice.
Co-Authors A. Muflihunna Alimuddin Ali Balqis Dinarty Jamaluddin M. Junda Maulyda Awwaliah P