Bella Fevi Aristia
Universitas Anwar Medika

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Gambaran Cakupan Vaksinasi/Imunisasi Dasar Lengkap Maulina Apriani; Defvi Nopitasari; Lavina Bella.F.; Imarotun Umamah; Muhammad Angga.P.; Bella Fevi Aristia; Alfu Laila; Eka Putri Nurhidayah; Khoirun Nisak
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.951

Abstract

Complete basic immunization (IDL) is a crucial preventive effort to increase children's immunity to various infectious diseases that can be prevented through immunization. In this research review, the literature analysis method was used to select ten journals that had titles and focus of discussion related to the overview of IDL coverage. These journals were identified in the 2015–2025 period through the Google Scholar, Crossref, and Garuda search engines with certain inclusion criteria. The results of the analysis showed that the coverage of IDL in several health facilities in Indonesia was quite high in the initial dose, especially in infants less than one year old. However, the achievement of the follow-up dose is still relatively lower than the first dose. Parents' ignorance about the benefits of immunization, concerns about vaccine side effects, limited access to health services, and delays in visit schedules are the main factors for incomplete immunization. In addition, socioeconomic factors and family support also affect immunization compliance. Therefore, it is necessary to strengthen the role of health workers through continuous education, community-based socialization, and improvement of the immunization recording and monitoring system to ensure the fulfillment of IDL evenly and sustainably.
Potensi Jintan Hitam (Nigella sativa) sebagai Agen Antibakteri terhadap Bakteri Patogen Klinis Allyssia Salma; Kadeq Novita Prajawanti; Bella Fevi Aristia; Khoirun Nisyak; Widji Soeratri
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.757

Abstract

Antibacterial substances such as thymoquinone, carvacrol, thymol, and p-cymene are found in black cumin (Nigella sativa), a type of herb. This study reviewed 12 recent scientific publications to assess the antibacterial efficacy of N. sativa against clinical pathogenic microorganisms. A comprehensive literature review of in vitro, in silico studies, and applications was conducted. The study found that black cumin extract and oil were more efficient against Gram-positive bacteria such as Staphylococcus aureus than Gram-negative bacteria such as Escherichia coli and Salmonella typhi. The antibacterial activity increased with the concentration of the extract, especially in the polar form (ethanol). Active compounds such as thymoquinone also showed high binding affinity to MRSA bacterial proteins molecularly. The application of N. sativa in the form of ointments, antibacterial textiles, and dental health products also showed good effectiveness. Based on these findings, Nigella sativa has great potential as a safe and environmentally friendly natural antibacterial alternative, although further clinical studies are needed to validate its efficacy and safety.