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Gambaran Cakupan Vaksinasi/Imunisasi Dasar Lengkap Maulina Apriani; Defvi Nopitasari; Lavina Bella.F.; Imarotun Umamah; Muhammad Angga.P.; Bella Fevi Aristia; Alfu Laila; Eka Putri Nurhidayah; Khoirun Nisak
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.951

Abstract

Complete basic immunization (IDL) is a crucial preventive effort to increase children's immunity to various infectious diseases that can be prevented through immunization. In this research review, the literature analysis method was used to select ten journals that had titles and focus of discussion related to the overview of IDL coverage. These journals were identified in the 2015–2025 period through the Google Scholar, Crossref, and Garuda search engines with certain inclusion criteria. The results of the analysis showed that the coverage of IDL in several health facilities in Indonesia was quite high in the initial dose, especially in infants less than one year old. However, the achievement of the follow-up dose is still relatively lower than the first dose. Parents' ignorance about the benefits of immunization, concerns about vaccine side effects, limited access to health services, and delays in visit schedules are the main factors for incomplete immunization. In addition, socioeconomic factors and family support also affect immunization compliance. Therefore, it is necessary to strengthen the role of health workers through continuous education, community-based socialization, and improvement of the immunization recording and monitoring system to ensure the fulfillment of IDL evenly and sustainably.
Potensi Jintan Hitam (Nigella sativa) sebagai Agen Antibakteri terhadap Bakteri Patogen Klinis Allyssia Salma; Kadeq Novita Prajawanti; Bella Fevi Aristia; Khoirun Nisyak; Widji Soeratri
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.757

Abstract

Antibacterial substances such as thymoquinone, carvacrol, thymol, and p-cymene are found in black cumin (Nigella sativa), a type of herb. This study reviewed 12 recent scientific publications to assess the antibacterial efficacy of N. sativa against clinical pathogenic microorganisms. A comprehensive literature review of in vitro, in silico studies, and applications was conducted. The study found that black cumin extract and oil were more efficient against Gram-positive bacteria such as Staphylococcus aureus than Gram-negative bacteria such as Escherichia coli and Salmonella typhi. The antibacterial activity increased with the concentration of the extract, especially in the polar form (ethanol). Active compounds such as thymoquinone also showed high binding affinity to MRSA bacterial proteins molecularly. The application of N. sativa in the form of ointments, antibacterial textiles, and dental health products also showed good effectiveness. Based on these findings, Nigella sativa has great potential as a safe and environmentally friendly natural antibacterial alternative, although further clinical studies are needed to validate its efficacy and safety.
EDUKASI PENCEGAHAN DAN PENGELOLAAN ASAM URAT MELALUI POLA MAKAN DAN GAYA HIDUP SEHAT PADA MASYARAKAT Adinugraha Amarullah; Ivan Charles Seran Klau; Yani Ambari Yani Ambari; Herni Setyawati Herni Setyawati; Bella Fevi Aristia; Yohanes Ardian Kapri Negara
Jurnal Abdi Masyarakat Kita Vol. 6 No. 1 (2026): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/asta.v6i1.917

Abstract

Abstract : Gout is one of the non-communicable diseases commonly found in the community and is closely associated with dietary patterns and lifestyle. Limited public knowledge regarding risk factors and preventive measures contributes to suboptimal gout management. This community service activity aimed to improve community knowledge on the prevention and management of gout through education on healthy dietary patterns and lifestyle modification. The activity employed a one-group design with health education delivered through interactive lectures, discussions, and educational media, conducted in the Tenggilis Mejoyo area, Surabaya. Knowledge evaluation was carried out using pretest and posttest questionnaires consisting of ten questions assessing understanding of gout, risk factors, high-purine foods, and the role of diet and lifestyle in gout prevention. The results showed an improvement in participants’ knowledge after the educational intervention. Prior to the activity, most participants had low (56.3 percent) and moderate (34.4 percent) knowledge levels; following the intervention, the proportion of participants with low knowledge decreased to 18.8 percent, while moderate and good knowledge levels increased to 53.1 percent and 28.1 percent, respectively. Participants also demonstrated better understanding of high-purine foods, the importance of physical activity, and sustainable gout management. In conclusion, community-based health education is effective as a promotive and preventive approach to improving public knowledge on gout prevention and management.
Uji Aktivitas Farmakologi Buah Jambu Biji (Psidium guajava L.) Sepbrilla Ananda K; Mulia Maharani; Virgiawan Kusuma; Firlia Nur Afifah; Bella Fevi Aristia
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 4 (2026): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i4.2341

Abstract

Guava (Psidium guajava L.) is a plant widely used in traditional medicine because it contains various bioactive compounds, such as flavonoids, phenolic compounds, tannins, alkaloids, terpenoids, lycopene, and vitamin C. These compounds are known to have various pharmacological activities that have the potential to support health. This opinion article aims to review and analyze the pharmacological activities of guava based on research results published in the period 2020–2025. The method used is a literature study of 11 national and international scientific journals selected according to the research topic. Data were analyzed descriptively by comparing findings regarding the biological activities of various plant parts, especially the fruit, fruit peel, and leaves. The results show that guava has various pharmacological activities, including antioxidant, antibacterial, antidiabetic, anticancer, anticholesterol, antimicrobial, and adaptogenic. Antioxidant activity is the most frequently reported effect, which is related to the high content of flavonoids, phenolic compounds, and vitamin C as free radical scavengers. Furthermore, several studies have shown that guava bioactive compounds can inhibit the activity of α-amylase and α-glucosidase enzymes, inhibit the growth of various pathogenic bacteria, and suppress the proliferation of cancer cells through various biological mechanisms. These findings indicate that guava has promising prospects for development as a raw material for herbal medicines and as a supportive therapy for various diseases. However, most of the available scientific evidence still comes from in vitro, in silico, and preclinical studies and therefore cannot be fully generalized to humans. Therefore, further research is needed, especially clinical trials with more comprehensive designs, to ensure the effectiveness, safety, optimal dosage, and potential use of guava in clinical practice.
Literatur Review: Analisis Tingkat Pengetahuan Masyarakat Di Indonesia Terhadap Beyond Use Date Obat Haya Avia Aunillah; Eka Aurya Agustina; Elit Juwita Ratu; Savillah Rensyanawati; Bella Fevi Aristia; Amellya Oktafiani; Ainul Ghurri
Sains Medisina Vol 4 No 5 (2026): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v4i5.1390

Abstract

Pengetahuan masyarakat mengenai penggunaan obat yang rasional merupakan aspek krusial dalam menjamin keamanan serta efektivitas terapi. Namun demikian, masih terdapat kesalah pahaman terkait beyond use date (BUD), terutama setelah kemasan obat dibuka atau dilakukan peracikan. Penelitian ini bertujuan untuk menganalisis hubungan tingkat pengetahuan masyarakat di Indonesia terhadap konsep BUD melalui pendekatan literature review. Metode yang digunakan berupa penelusuran literatur dari berbagai basis data ilmiah, seperti Google Scholar, dan ResearchGate dengan rentang publikasi tahun 2023–2025 menggunakan kata kunci yang relevan, seperti “beyond use date”, “tingkat pengetahuan masyarakat”, dan “penyimpanan obat”. Hasil kajian menunjukkan bahwa tingkat pengetahuan masyarakat terhadap BUD masih berada pada kategori rendah hingga sedang. Faktor-faktor yang mempengaruhi meliputi tingkat pendidikan, sumber informasi, serta peran tenaga kesehatan dalam memberikan edukasi. Rendahnya tingkat pemahaman tersebut berpotensi menyebabkan kesalahan dalam penyimpanan dan penggunaan obat, yang pada akhirnya dapat menurunkan efektivitas terapi serta meningkatkan risiko terjadinya efek samping. Oleh karena itu, diperlukan peningkatan edukasi yang berkelanjutan dari tenaga kesehatan, khususnya apoteker, guna meningkatkan pemahaman masyarakat dalam penggunaan obat yang aman dan rasional.