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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Journal of Science and Science Education (JoSSEd)
Susanna Halim
Prima Indonesia University
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Materials Science & Nanotechnology Neuroscience Physics

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Potensi Daya Inhibisi Ekstrak Etanol Daun Sirih Merah (Piper crocatum Ruiz & Pav) Terhadap Mikroorganisme Pada Biofilm Di Pelat Gigi Tiruan Berbahan Hot Curing Acrylic Susanna Halim; Gusbakti Rusip; Siti Farah Syarbaini
Jurnal Penelitian Pendidikan IPA Vol 11 No 3 (2025): March
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i3.10825

Abstract

Tooth loss reduces quality of life by affecting chewing and speech function and can interfere with social activities. Hot curing acrylic dentures have the disadvantage of high porosity and surface roughness, so they are susceptible to food residues and microorganisms that can lead to the formation of biofilm and denture stomatitis. Red series leaves (Piper crocatum Ruiz & Pav) have chemical content such as flavonoids, alkaloids, and essential oils that have the potential to be antimicrobials. This study aims to determine the potential of red betel leaf ethanol extract in inhibiting microorganisms in biofilms in denture plates made of hot curing acrylic. This study used the liquid dilution method to test the effectiveness of red betel leaf ethanol extract with concentrations of 10%, 25%, 50% and 75% on the growth of Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans contaminated on round denture plates made of hot curing acrylic. The results showed that the ethanol extract of red betel leaf significantly reduced the number of bacterial and fungal colonies, with a concentration of 75% showing the highest effectiveness, especially against the bacterium Lactobacillus acidophilus with an average colony count of 45.67 ± 4.04. Red betel leaf ethanol extract contains chemical compounds that are effective as antimicrobials in biofilms in denture plates made of hot curing acrylic. This extract has the potential to be an alternative natural ingredient for denture cleaning.
Atypical Odontalgia: Case Review and Literature on Variations in Clinical Features and Therapeutic Response Susanna Halim; Ivanka Ivanka
Journal of Science and Science Education Vol. 7 No. 1 (2026)
Publisher : Pascasarjana, Mataram University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jossed.v7i1.12786

Abstract

Atypical Odontalgia (AO) is a complex chronic pain condition, characterized by tooth or tooth socket pain without a clear clinical or radiographic cause. This condition, also known as phantom tooth pain or persistent dentoalveolar pain disorder, poses a diagnostic challenge for dental practitioners, often leading patients to undergo multiple ineffective dental procedures. To review variations in clinical features of AO and diverse therapeutic responses based on data from various journals. AO is highly variable in presentation, including pain described as heavy, splitting, stabbing, burning, or electric shock-like. The pain may be unilateral or bilateral, difficult to localize, and often significantly affects patients’ quality of life. Psychiatric comorbidities in AO patients, including depression and anxiety disorders, can worsen the condition. Reports also suggest associations between AO and neurodevelopmental disorders such as ADHD and ASD, highlighting the importance of a holistic approach in diagnosis and management. Therapeutically, AO shows heterogeneous responses to various interventions. Antidepressants such as amitriptyline have been reported effective, though patient responses vary. Other cases show successful outcomes with atypical antipsychotics such as aripiprazole, either as monotherapy or in combination with mirtazapine. Another approach under investigation is the use of OnabotulinumtoxinA (OnabotA), which has shown promising results in reducing pain intensity in AO patients without significant side effects. Psychological therapies and behavioral support are also considered crucial, especially when psychiatric comorbidities are present, to improve treatment outcomes and patients’ quality of life. A deeper understanding of AO’s clinical variability and therapeutic responses is essential for more accurate diagnosis and effective management
Co-Authors Gusbakti Rusip Ivanka Ivanka Siti Farah Syarbaini