Rita Evalina
Universitas Sumatera Utara & Adam Malik Hospital

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Antibiotic Resistance in the Pediatric Intensive Care Unit: Literature Review Nina Melina Ginting; Hendri Wijaya; Arlinda Sari Wahyuni; Yunnie Trisnawati; Rita Evalina; Ayodhia Pitaloka Pasaribu
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6087

Abstract

Antibiotics have been overused, the unwise use of antibiotics has become a special concern and has led to resistance. Almost 50% of antibiotic therapy is initiated inappropriately and without correct identification of the etiological agent. The high number of inappropriate antibiotic prescriptions contributes to the occurrence of antibiotic resistance and increased risk of death. MDR pathogens result in a 40% increase in mortality in hospital-acquired infections. The purpose of this study was to discuss the pattern of the resistance of antibiotic therapy in pediatric patients admitted to the PICU. Method: The search strategy was conducted through three databases (Google Scholar, Pubmed, Science Direct) which published during 2015-2025, using MeSH words “Antibiotic Resistance” AND “Pediatric intensive care unit”. There were thousand studies found, then by using the PRISMA flowchart, which total ten studies were included. PICU has a higher ratio of pathogen composition and bacterial resistance. Many factors can lead to antibiotic resistance, it might be caused by unnecessary or suboptimal prescribed antibiotic therapy from community before, previous health care and the hospital itself. The high number of inappropriate antibiotic prescriptions contributes to the occurrence of antibiotic resistance. Antibiotic resistance can lead to longer hospital stays and increased risk of mortality.
Association Between Glycaemic Control and Cardiac Function in Children with Diabetes Mellitus M Ridho; Siska Mayasari Lubis; Putri Amelia; Juliandi Harahap; Rita Evalina; Fathia Meirina
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7020

Abstract

The prevalence of Diabetes Mellitus (DM) among children and adolescents has been progressively increasing, with Type 1 DM constituting the majority of cases. Cardiovascular disease (CVD) is a major long-term complication, yet early cardiac involvement remains poorly understood in this population. This study aimed to assess the association between glycaemic control and cardiac function in paediatric patients with DM. A cross-sectional observational study was conducted involving 30 children with type 1 or type 2 DM at H. Adam Malik General Hospital, Medan. Glycaemic control was assessed using HbA1c levels. Cardiac function was evaluated using electrocardiography (ECG) and echocardiographic parameters, including ejection fraction (EF), fractional shortening (FS), tricuspid annular plane systolic excursion (TAPSE), and E/A ratio. Data were analysed using Chi-Square and Mann-Withney Test. Most subjects (90%) had poor glycaemic control (HbA1c ≥7%). Cardiac dysfunction (reduced EF <55%) was identified in 16.7% of patients. However, no statistically significant associations were found between cardiac function and HbA1c, duration of diagnosis, blood pressure, or body mass index (BMI) (p>0.05). There was no significant relationship was found between glycaemic control and cardiac function, highlighting the need for more sensitive diagnostic tools and long-term follow-up to detect subclinical cardiovascular complications.