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All Journal Indonesian Journal of Global Health research International Journal of Community Service
Silphia Novelyn
Universitas Kristen Indonesia
Religion Humanities Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Nursing Public Health Social Sciences Other

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Morphology Profile and PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Patients Marliana Nurprilinda; Silphia Novelyn; Sonya Trinur Veronika Siahaan; Frisca Angreni
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6167

Abstract

Lung cancer cases in Indonesia became the second highest with the highest mortality rate in 2022. Various advanced examinations such as histopathology and immunohistochemistry are performed to identify the morphological types of lung cancer. Histopathologically, lung cancer classified into two types are Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC). After histopathological examination, further immunohistochemical testing is required to help classify the subtype and identify therapeutic markers. One of the markers is the expression of Programmed Death Ligand 1 (PD-L1). Patients with this marker can receive anti-PD-L1 immunotherapy according to the specified criteria. This study determined the morphological profile and PD-L1 expression in patients with Non-Small Cell Lung Cancer (NSCLC) at Siloam MRCCC Semanggi Hospital between 2020 and 2022. The method used was descriptive with a retrospective approach by collecting data from the archives of the Anatomical Pathology Laboratory at Siloam MRCCC Semanggi Hospital. The population in this study comprised all patients diagnosed with NSCLC who underwent PD-L1 IHC testing at Siloam MRCCC Semanggi Hospital between 2020 and 2022. Data collection was conducted using a total sampling method, including all individuals who met the predefined inclusion and exclusion criteria. The final sample consisted of 91 patients diagnosed with NSCLC who had undergone PD-L1 IHC examination during the 2020–2022 period. A total of 91 patients including the inclusion and exclusion criteria were included in the data and analyzed. The analysis revealed that the age group 60-69 years accounted for 39.5% of cases, 54.9% of cases were male, 73.6% of cases had an adenocarcinoma morphology, and 54.9% of cases had a negative PD-L1. The incidence of NSCLC patients who underwent PD-L1 IHK examination based on age was dominated by the 60-69 year age group, and most of them were male with the most common diagnosis being adenocarcinoma morphology type and PD-L1 expression with negative values.
Counseling on Iron Deficiency Anemia in Pregnant Women as an Effort to Prevent Stunting in Sukasirnarasa Village Yunita R.M.B Sitompul; Amanda Sintabella; Silphia Novelyn; Benaya Putra; Lucyana Lettisia Apriliani
International Journal Of Community Service Vol. 5 No. 2 (2025): May 2025 (Indonesia - Malaysia - Timor-Leste)
Publisher : CV. Inara in Colaboration with www.stie-sampit.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v5i2.852

Abstract

Stunting and anemia are quite serious public health problems, especially in areas with high poverty rates and limited access to health services. Several contributing factors include lack of knowledge about nutrition, unbalanced diets, and limited access to health services. One of the factors that contributes to stunting is anemia in pregnant women. Given these conditions, efforts are needed to increase public understanding of anemia and stunting and prevent stunting from pregnancy. These efforts were realized through health education activities carried out in September 2023 in Sukasirnarasa Village, Sumedang Regency, West Java. Participants were 10 posyandu cadres and pregnant women. The service activity was in the form of education about iron deficiency anemia. The success of this activity was evaluated through measuring achievement indicators using a pretest and posttest with a true-false test type. The evaluation results showed an increase in participant understanding by 15.7% after participating in the education. This increase indicates that health education activities regarding stunting prevention through anemia prevention in pregnant women have been successfully implemented and achieved the expected goals..
Co-Authors Amanda Sintabella Benaya Putra Frisca Angreni Lucyana Lettisia Apriliani Marliana Nurprilinda Sonya Trinur Veronika Siahaan Yunita R.M.B Sitompul