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All Journal MEDICA (International Medical Scientific Journal)
Emilda Sari
Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Pontianak, Pontianak, West Kalimantan, Indonesia
Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Factors Associated with Hyperbilirubinemia in Newborns at Tanjungpura University Hospital, Pontianak Anggita Ria Panjaitan; Sri Tumpuk; Emilda Sari; Mohd Yunus
MEDICA (International Medical Scientific Journal) Vol. 7 No. 1 (2025): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i1.485

Abstract

In Indonesia, neonatal death is often caused by low birth weight, asphyxia, birth trauma, hyperbilirubinemia, infections, and congenital abnormalities. Hyperbilirubinemia in neonates generally occurs due to the immaturity of organs in processing bilirubin, with phototherapy as the primary treatment. Recent studies have shown an increase in cases of hyperbilirubinemia at Tanjungpura University Hospital in Pontianak, highlighting the need for further research on the factors influencing this condition. The aim of this study is to analyze the factors associated with hyperbilirubinemia in newborns at Tanjungpura University Hospital in Pontianak. This research used an analytical observational design with a cross-sectional approach. The sample consisted of 67 respondents selected through total sampling. The distribution of maternal gestational age showed 49.3% preterm and 50.7% term. Of the respondents, 50.7% had ABO incompatibility, while 49.3% did not. A total of 58.2% of the newborns had normal birth weight, while 41.8% did not. Regarding delivery type, 67.5% were delivered by cesarean section (C-section), and 34.3% by normal delivery. The results of the Chi-Square Continuity Correction test showed p=0.038 for gestational age, p=0.018 for ABO incompatibility, p=0.001 for birth weight, and p=0.202 for delivery type. In conclusion, there is a significant relationship between gestational age, ABO incompatibility, and birth weight with the occurrence of hyperbilirubinemia, but no significant relationship with the type of delivery.
The Antibacterial Effectiveness of Moringa Oleifera Leaves Extract Against the Growth of Escherichia coli Using the Diffusion Method Liza Harum Nur Annisa; Linda Triana; Emilda Sari; Ari Nuswantoro
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.487

Abstract

Moringa oleifera leaves a common herbal plant found in tropical regions and naturalized in Indonesia, are known to be rich in bioactive compounds such as flavonoids, tannins, terpenoids, alkaloids, and saponins. These compounds have potential medicinal properties, including antibacterial activity. This study aims to examine the antibacterial effectiveness of moringa leaf extract against the growth of Escherichia coli using the diffusion method. This descriptive-analytical research employed a purposive sampling technique with varying concentrations of moringa leaf extract: 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100%. Each concentration was tested in triplicate, resulting in a total of 30 samples. The antibacterial effectiveness test was conducted using the agar diffusion method with blank paper disks. The results showed that no inhibition zones were formed at concentrations of 10% and 20%. Inhibition zones began to appear at 30% concentration (7.3 mm), increasing with higher concentrations: 40% (9 mm), 50% (10.3 mm), 60% (11.3 mm), 70% (16.6 mm), 80% (23.3 mm), 90% (28.3 mm), and reaching 34.6 mm at 100% concentration. Based on the antibacterial activity category, 10% and 20% showed no activity, 30% and 40% were categorized as weak, 50% and 60% as moderate, 70% as strong, and 80%, 90%, and 100% as very strong. It can be concluded that an 80% concentration of moringa leaf extract is the most effective in inhibiting the growth of Escherichia coli.
Description of Total Protein Levels in Pregnant Women at the Tambelan Sampit Health Center, Pontianak Matius Sunti; Sutriswanto Sutriswanto; Emilda Sari
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.490

Abstract

Pregnancy is a critical period characterized by the growth and development of the fetus, during which the nutritional needs of the mother, including total protein intake, increase significantly. Total protein in the blood comprises albumin, globulin, and small amounts of other proteins, all essential for maternal and fetal health. This descriptive-analytic study aimed to determine the total protein levels in pregnant women attending the Tambelan Sampit Health Center. The study involved 30 pregnant women, including 9 in the first trimester, 10 in the second trimester, and 11 in the third trimester. Data were collected without generalization analysis to describe the condition of the study population. The highest total protein levels were observed in the first trimester (8.2 g/dL), followed by the third trimester (7.3 g/dL), and the second trimester (7.1 g/dL). In the first trimester, 55.6% of participants had normal protein levels, and 44.4% had abnormal levels. In the second trimester, 80% had normal levels, and 20% had abnormal levels. In the third trimester, 81.9% showed normal levels, and 18.1% had abnormal levels. It can be concluded that most of the pregnant women in this study had total protein levels within the normal range across all trimesters. Further research is recommended to conduct a more in-depth investigation of total protein levels during pregnancy.
Co-Authors Anggita Ria Panjaitan Ari Nuswantoro Linda Triana Liza Harum Nur Annisa Matius Sunti Mohd Yunus Sri Tumpuk Sutriswanto Sutriswanto