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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biosilampari: Jurnal Biologi
Winda Shari
Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Immunology & microbiology Materials Science & Nanotechnology Physics

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Potential of Liquid Smoke in Inhibiting the Growth of Pathogenic Bacteria: A Mini Review Khusnul Azizah; Winda Shari; Charles Banon; Avidlyandi Avidlyandi; Khafit Wiradimafan; Salprima Yudha S.; Morina Adfa
Jurnal Biosilampari : Jurnal Biologi Vol 7 No 2 (2025): Biosilampari: Jurnal Biologi
Publisher : Universitas PGRI Silampari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62112/biosilampari.v7i2.162

Abstract

The objective of this study was to perform a comprehensive evaluation of the application of liquid smoke as a possible antibacterial agent. The studies were identified by conducting searches on multiple electronic databases, specifically Semantic Scholar, PubMed, and Google Scholar, from 2013 to 2024. The keywords used included ‘antibacterial of wood vinegar, antibacterial of pyroligneous extract, antibacterial of pyroligneous acid, antibacterial of wood distillate, antibacterial activity of liquid smoke, and aktivitas antibakteri asap cair (in Bahasa Indonesia)’. The results indicate that liquid smoke has the capacity to serve as a natural antibacterial agent against both Gram positive and Gram-negative microorganisms. The variation in antibacterial susceptibility may arise from the composition of chemical compounds present in liquid smoke, the raw materials employed in its production, the temperature of pyrolysis, and the specific testing methodology employed. This review will be useful to the industrial and scientific communities in the food science, pharmaceutical, and technology fields.
Potential Antagonistic Interactions of Cassia alata L. Leaf Extract and Commercial Antibiotics against Staphylococcus aureus: An In Vitro Evaluation Oki Rokhim Mawakhid; Putri Ramanda; Samuel Billie Tua Sinaga; Winda Shari; Avidlyandi Avidlyandi; Khafit Wiradimafan; Salprima Yudha S.; Risky Hadi Wibowo; Morina Adfa
Jurnal Penelitian Pendidikan IPA Vol 12 No 5 (2026): In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i5.14500

Abstract

Several in vitro studies have demonstrated that the combination of plant extracts with antibiotics may reduce the minimum inhibitory concentration (MIC) of antibiotics against resistant microorganisms. Interactions between plant extracts and antibiotics can be synergistic, additive, or antagonistic. This study aimed to evaluate the potential interaction between Cassia alata leaves methanol extract and five selected conventional antibiotics in inhibiting the growth of Staphylococcus aureus ATCC 29213. Antibacterial activity was assessed using the well diffusion and paper strip methods. The methanol extract of C. alata leaves, when tested singly at a concentration of 100 mg/mL, produced an average inhibition zone of 11.74 mm. Four antibiotics, namely ciprofloxacin, clindamycin, chloramphenicol, and tetracycline, exhibited stronger antibacterial activity with inhibition zones ranging from 19.56–27.26 mm, whereas co-trimoxazole showed no inhibitory effect. The combination of C. alata leaves methanol extract with ciprofloxacin, clindamycin, chloramphenicol, tetracycline, and cotrimoxazole resulted in inhibition zones of 22.26 ± 0.703 mm, 22.54 ± 1.222 mm, 17.91 ± 1.094 mm, 17.57 ± 0.652 mm, and 9.30 ± 1.180 mm, respectively. The combined treatments have potential antagonistic effects, as the inhibition zones were smaller than the sum of the individual activities of the extract and antibiotics. Therefore, the combination was considered less effective in suppressing growth of S. aureus ATCC 29213
Co-Authors Avidlyandi, Avidlyandi Charles Banon Khafit Wiradimafan Khusnul Azizah Morina Adfa Oki Rokhim Mawakhid Putri Ramanda Risky Hadi Wibowo Salprima Yudha S. Samuel Billie Tua Sinaga